Eric. Chiao, et.al., Overgrowth of a mouse model of the Simpson-Golabi-Behmel syndrome is independent of IGF signaling., Developmental biology, 2002, 243

http://rdf.ncbi.nlm.nih.gov/pubmed/11846487

Eric. Chiao, et.al., Overgrowth of a mouse model of the Simpson-Golabi-Behmel syndrome is independent of IGF signaling., Developmental biology, 2002, 243

pubmed

allele

http://purl.org/net/cito/citesAsAuthority

• Gpc3<tm1Arge>
  http://metadb.riken.jp/db/mgi_rdf/MGI:2657134

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• perinatal lethality, incomplete penetrance_Gpc3<tm1Arge>/Gpc3<tm1Arge>,Igf1<tm1Arge>/Igf1<tm1Arge>
  http://metadb.riken.jp/0011090I129SSvEv129S1SvC57BL6JDBAMF1Gpc3tm1ArgeGpc3tm1ArgeIgf1tm1ArgeIgf1tm1ArgeIgf1tm1ArgeGpc3tm1Arge
• abnormal hindlimb morphology_Gpc3<tm1Arge>/Gpc3<tm1Arge>,Igf1r<tm1Arge>/Igf1r<tm1Arge>
  http://metadb.riken.jp/0000556I129SSvEv129S1SvC57BL6JGpc3tm1ArgeGpc3tm1ArgeIgf1rtm1ArgeIgf1rtm1ArgeIgf1rtm1ArgeGpc3tm1Arge
• asymmetric sternocostal joints_Gpc3<tm1Arge>/Y
  http://metadb.riken.jp/0008146EI129SSvEv129S1SvorI129S1SvC57BL6JGpc3tm1ArgeYGpc3tm1Arge
• rib fusion_Gpc3<tm1Arge>/Y,H19<tm1Tilg>/H19<+>
  http://metadb.riken.jp/0000154I129SSvEv129S1SvGpc3tm1ArgeYH19tm1TilgH19H19tm1TilgGpc3tm1ArgeH19
• postnatal growth retardation_Gpc3<tm1Arge>/Y
  http://metadb.riken.jp/0001732EI129SSvEv129S1SvorI129S1SvC57BL6JGpc3tm1ArgeYGpc3tm1Arge
• abnormal kidney morphology_Gpc3<tm1Arge>/Y
  http://metadb.riken.jp/0002135EI129SSvEv129S1SvorI129S1SvC57BL6JGpc3tm1ArgeYGpc3tm1Arge
• polydactyly_Gpc3<tm1Arge>/Y
  http://metadb.riken.jp/0000562EI129SSvEv129S1SvorI129S1SvC57BL6JGpc3tm1ArgeYGpc3tm1Arge
• white spotting_Gpc3<tm1Arge>/Gpc3<tm1Arge>
  http://metadb.riken.jp/0002938EI129SSvEv129S1SvorI129S1SvC57BL6JGpc3tm1ArgeGpc3tm1ArgeGpc3tm1Arge
• abnormal hindlimb morphology_Gpc3<tm1Arge>/Y,Igf1r<tm1Arge>/Igf1r<tm1Arge>
  http://metadb.riken.jp/0000556I129SSvEv129S1SvC57BL6JGpc3tm1ArgeYIgf1rtm1ArgeIgf1rtm1ArgeIgf1rtm1ArgeGpc3tm1Arge
• distended abdomen_Gpc3<tm1Arge>/Y
  http://metadb.riken.jp/0001270EI129SSvEv129S1SvorI129S1SvC57BL6JGpc3tm1ArgeYGpc3tm1Arge
• increased placenta weight_H19<tm1Tilg>/H19<+>
  http://metadb.riken.jp/0004920I129SSvEvH19tm1TilgH19H19H19tm1Tilg
• kidney medulla cysts_Gpc3<tm1Arge>/Y
  http://metadb.riken.jp/0011307EI129SSvEv129S1SvorI129S1SvC57BL6JGpc3tm1ArgeYGpc3tm1Arge
• postnatal lethality, incomplete penetrance_Gpc3<tm1Arge>/Gpc3<tm1Arge>,H19<tm1Tilg>/H19<+>
  http://metadb.riken.jp/0011086I129SSvEv129S1SvGpc3tm1ArgeGpc3tm1ArgeH19tm1TilgH19H19tm1TilgGpc3tm1ArgeH19
• kidney cysts_Gpc3<tm1Arge>/Y
  http://metadb.riken.jp/0003675EI129SSvEv129S1SvorI129S1SvC57BL6JGpc3tm1ArgeYGpc3tm1Arge
• paternal imprinting_Gpc3<tm1Arge>/Gpc3<tm1Arge>,H19<tm1Tilg>/H19<+>
  http://metadb.riken.jp/0003123I129SSvEv129S1SvGpc3tm1ArgeGpc3tm1ArgeH19tm1TilgH19H19tm1TilgGpc3tm1ArgeH19
• increased body weight_H19<tm1Tilg>/H19<+>
  http://metadb.riken.jp/0001260I129SSvEvH19tm1TilgH19H19H19tm1Tilg
• increased body weight_Gpc3<tm1Arge>/Y
  http://metadb.riken.jp/0001260EI129SSvEv129S1SvorI129S1SvC57BL6JGpc3tm1ArgeYGpc3tm1Arge
• decreased spleen weight_Gpc3<tm1Arge>/Y
  http://metadb.riken.jp/0004953EI129SSvEv129S1SvorI129S1SvC57BL6JGpc3tm1ArgeYGpc3tm1Arge
• abnormal kidney medulla morphology_Gpc3<tm1Arge>/Y
  http://metadb.riken.jp/0003014EI129SSvEv129S1SvorI129S1SvC57BL6JGpc3tm1ArgeYGpc3tm1Arge
• abnormal calcaneum morphology_Gpc3<tm1Arge>/Y,Igf1r<tm1Arge>/Igf1r<tm1Arge>
  http://metadb.riken.jp/0009728I129SSvEv129S1SvC57BL6JGpc3tm1ArgeYIgf1rtm1ArgeIgf1rtm1ArgeIgf1rtm1ArgeGpc3tm1Arge
• perinatal lethality, complete penetrance_Gpc3<tm1Arge>/Y,Igf1r<tm1Arge>/Igf1r<tm1Arge>
  http://metadb.riken.jp/0011089I129SSvEv129S1SvC57BL6JGpc3tm1ArgeYIgf1rtm1ArgeIgf1rtm1ArgeIgf1rtm1ArgeGpc3tm1Arge
• increased rib number_Gpc3<tm1Arge>/Y,H19<tm1Tilg>/H19<+>
  http://metadb.riken.jp/0000480I129SSvEv129S1SvGpc3tm1ArgeYH19tm1TilgH19H19tm1TilgGpc3tm1ArgeH19
• kidney corticomedullary cysts_Gpc3<tm1Arge>/Y
  http://metadb.riken.jp/0011308EI129SSvEv129S1SvorI129S1SvC57BL6JGpc3tm1ArgeYGpc3tm1Arge
• increased placenta weight_Gpc3<tm1Arge>/Y,H19<tm1Tilg>/H19<+>
  http://metadb.riken.jp/0004920I129SSvEv129S1SvGpc3tm1ArgeYH19tm1TilgH19H19tm1TilgGpc3tm1ArgeH19
• abnormal body size_Gpc3<tm1Arge>/Gpc3<+>,Igf2<tm1Rob>/Igf2<+>
  http://metadb.riken.jp/0003956I129SSvEv129S1SvC57BL6JGpc3tm1ArgeGpc3Igf2tm1RobIgf2Gpc3tm1ArgeIgf2Gpc3Igf2tm1Rob
• omphalocele_Gpc3<tm1Arge>/Y,H19<tm1Tilg>/H19<+>
  http://metadb.riken.jp/0003052I129SSvEv129S1SvGpc3tm1ArgeYH19tm1TilgH19H19tm1TilgGpc3tm1ArgeH19
• postnatal lethality, complete penetrance_Gpc3<tm1Arge>/Y,Igf1<tm1Arge>/Igf1<tm1Arge>
  http://metadb.riken.jp/0011085I129SSvEv129S1SvC57BL6JDBAMF1Gpc3tm1ArgeYIgf1tm1ArgeIgf1tm1ArgeIgf1tm1ArgeGpc3tm1Arge
• increased body weight_Gpc3<tm1Arge>/Y,H19<tm1Tilg>/H19<+>
  http://metadb.riken.jp/0001260I129SSvEv129S1SvGpc3tm1ArgeYH19tm1TilgH19H19tm1TilgGpc3tm1ArgeH19
• perinatal lethality, complete penetrance_Gpc3<tm1Arge>/Gpc3<tm1Arge>,Igf1r<tm1Arge>/Igf1r<tm1Arge>
  http://metadb.riken.jp/0011089I129SSvEv129S1SvC57BL6JGpc3tm1ArgeGpc3tm1ArgeIgf1rtm1ArgeIgf1rtm1ArgeIgf1rtm1ArgeGpc3tm1Arge
• maternal imprinting_Gpc3<tm1Arge>/Y,Igf2<tm1Rob>/Igf2<+>
  http://metadb.riken.jp/0003122I129SSvEv129S1SvC57BL6JGpc3tm1ArgeYIgf2tm1RobIgf2Gpc3tm1ArgeIgf2Igf2tm1Rob
• decreased body weight_Igf2<tm1Rob>/Igf2<+>
  http://metadb.riken.jp/0001262I129SSvEvIgf2tm1RobIgf2Igf2Igf2tm1Rob
• perinatal lethality, incomplete penetrance_Gpc3<tm1Arge>/Gpc3<tm1Arge>,H19<tm1Tilg>/H19<+>
  http://metadb.riken.jp/0011090I129SSvEv129S1SvGpc3tm1ArgeGpc3tm1ArgeH19tm1TilgH19H19tm1TilgGpc3tm1ArgeH19
• increased placental labyrinth size_Gpc3<tm1Arge>/Y
  http://metadb.riken.jp/0011520EI129SSvEv129S1SvorI129S1SvC57BL6JGpc3tm1ArgeYGpc3tm1Arge
• postnatal lethality, complete penetrance_Gpc3<tm1Arge>/Gpc3<tm1Arge>,Igf1<tm1Arge>/Igf1<tm1Arge>
  http://metadb.riken.jp/0011085I129SSvEv129S1SvC57BL6JDBAMF1Gpc3tm1ArgeGpc3tm1ArgeIgf1tm1ArgeIgf1tm1ArgeIgf1tm1ArgeGpc3tm1Arge
• absent mandible_Gpc3<tm1Arge>/Y
  http://metadb.riken.jp/0000087EI129SSvEv129S1SvorI129S1SvC57BL6JGpc3tm1ArgeYGpc3tm1Arge
• paternal imprinting_Gpc3<tm1Arge>/Y,H19<tm1Tilg>/H19<+>
  http://metadb.riken.jp/0003123I129SSvEv129S1SvGpc3tm1ArgeYH19tm1TilgH19H19tm1TilgGpc3tm1ArgeH19
• perinatal lethality, incomplete penetrance_Gpc3<tm1Arge>/Y,Igf1<tm1Arge>/Igf1<tm1Arge>
  http://metadb.riken.jp/0011090I129SSvEv129S1SvC57BL6JDBAMF1Gpc3tm1ArgeYIgf1tm1ArgeIgf1tm1ArgeIgf1tm1ArgeGpc3tm1Arge
• belly spot_Gpc3<tm1Arge>/Gpc3<tm1Arge>
  http://metadb.riken.jp/0000373EI129SSvEv129S1SvorI129S1SvC57BL6JGpc3tm1ArgeGpc3tm1ArgeGpc3tm1Arge
• postnatal lethality, incomplete penetrance_Gpc3<tm1Arge>/Gpc3<tm1Arge>
  http://metadb.riken.jp/0011086EI129SSvEv129S1SvorI129S1SvC57BL6JGpc3tm1ArgeGpc3tm1ArgeGpc3tm1Arge
• belly spot_Gpc3<tm1Arge>/Y
  http://metadb.riken.jp/0000373EI129SSvEv129S1SvorI129S1SvC57BL6JGpc3tm1ArgeYGpc3tm1Arge
• perinatal lethality, incomplete penetrance_Gpc3<tm1Arge>/Y,H19<tm1Tilg>/H19<+>
  http://metadb.riken.jp/0011090I129SSvEv129S1SvGpc3tm1ArgeYH19tm1TilgH19H19tm1TilgGpc3tm1ArgeH19
• postnatal lethality, incomplete penetrance_Gpc3<tm1Arge>/Y,H19<tm1Tilg>/H19<+>
  http://metadb.riken.jp/0011086I129SSvEv129S1SvGpc3tm1ArgeYH19tm1TilgH19H19tm1TilgGpc3tm1ArgeH19
• kidney cortex cysts_Gpc3<tm1Arge>/Y
  http://metadb.riken.jp/0000522EI129SSvEv129S1SvorI129S1SvC57BL6JGpc3tm1ArgeYGpc3tm1Arge
• white spotting_Gpc3<tm1Arge>/Y
  http://metadb.riken.jp/0002938EI129SSvEv129S1SvorI129S1SvC57BL6JGpc3tm1ArgeYGpc3tm1Arge
• increased placenta weight_Gpc3<tm1Arge>/Y
  http://metadb.riken.jp/0004920EI129SSvEv129S1SvorI129S1SvC57BL6JGpc3tm1ArgeYGpc3tm1Arge
• increased placenta weight_Gpc3<tm1Arge>/Gpc3<tm1Arge>
  http://metadb.riken.jp/0004920EI129SSvEv129S1SvorI129S1SvC57BL6JGpc3tm1ArgeGpc3tm1ArgeGpc3tm1Arge
• abnormal intestine morphology_Gpc3<tm1Arge>/Y
  http://metadb.riken.jp/0000477EI129SSvEv129S1SvorI129S1SvC57BL6JGpc3tm1ArgeYGpc3tm1Arge
• abnormal sternum ossification_Gpc3<tm1Arge>/Y,H19<tm1Tilg>/H19<+>
  http://metadb.riken.jp/0008277I129SSvEv129S1SvGpc3tm1ArgeYH19tm1TilgH19H19tm1TilgGpc3tm1ArgeH19
• dilated renal tubules_Gpc3<tm1Arge>/Y
  http://metadb.riken.jp/0002705EI129SSvEv129S1SvorI129S1SvC57BL6JGpc3tm1ArgeYGpc3tm1Arge
• hydronephrosis_Gpc3<tm1Arge>/Y
  http://metadb.riken.jp/0000519EI129SSvEv129S1SvorI129S1SvC57BL6JGpc3tm1ArgeYGpc3tm1Arge
• hypoglycemia_Gpc3<tm1Arge>/Y
  http://metadb.riken.jp/0000189EI129SSvEv129S1SvorI129S1SvC57BL6JGpc3tm1ArgeYGpc3tm1Arge
• belly spot_Gpc3<tm1Arge>/Gpc3<+>
  http://metadb.riken.jp/0000373EI129SSvEv129S1SvorI129S1SvC57BL6JGpc3tm1ArgeGpc3Gpc3tm1ArgeGpc3
• postnatal lethality, incomplete penetrance_Gpc3<tm1Arge>/Y
  http://metadb.riken.jp/0011086EI129SSvEv129S1SvorI129S1SvC57BL6JGpc3tm1ArgeYGpc3tm1Arge
• abnormal spleen B cell follicle morphology_Gpc3<tm1Arge>/Y
  http://metadb.riken.jp/0008470EI129SSvEv129S1SvorI129S1SvC57BL6JGpc3tm1ArgeYGpc3tm1Arge
• abnormal body size_Gpc3<tm1Arge>/Y,Igf2<tm1Rob>/Igf2<+>
  http://metadb.riken.jp/0003956I129SSvEv129S1SvC57BL6JGpc3tm1ArgeYIgf2tm1RobIgf2Gpc3tm1ArgeIgf2Igf2tm1Rob
• abnormal enzyme/coenzyme activity_Gpc3<tm1Arge>/Y
  http://metadb.riken.jp/0005584EI129SSvEv129S1SvorI129S1SvC57BL6JGpc3tm1ArgeYGpc3tm1Arge
• maternal imprinting_Gpc3<tm1Arge>/Gpc3<+>,Igf2<tm1Rob>/Igf2<+>
  http://metadb.riken.jp/0003122I129SSvEv129S1SvC57BL6JGpc3tm1ArgeGpc3Igf2tm1RobIgf2Gpc3tm1ArgeIgf2Gpc3Igf2tm1Rob
• small spleen_Gpc3<tm1Arge>/Y
  http://metadb.riken.jp/0000692EI129SSvEv129S1SvorI129S1SvC57BL6JGpc3tm1ArgeYGpc3tm1Arge
• split xiphoid process_Gpc3<tm1Arge>/Y,H19<tm1Tilg>/H19<+>
  http://metadb.riken.jp/0004678I129SSvEv129S1SvGpc3tm1ArgeYH19tm1TilgH19H19tm1TilgGpc3tm1ArgeH19
• asymmetric sternocostal joints_Gpc3<tm1Arge>/Y,H19<tm1Tilg>/H19<+>
  http://metadb.riken.jp/0008146I129SSvEv129S1SvGpc3tm1ArgeYH19tm1TilgH19H19tm1TilgGpc3tm1ArgeH19
• paternal imprinting_H19<tm1Tilg>/H19<+>
  http://metadb.riken.jp/0003123I129SSvEvH19tm1TilgH19H19H19tm1Tilg
• kidney cortex atrophy_Gpc3<tm1Arge>/Y
  http://metadb.riken.jp/0011423EI129SSvEv129S1SvorI129S1SvC57BL6JGpc3tm1ArgeYGpc3tm1Arge
• abnormal calcaneum morphology_Gpc3<tm1Arge>/Gpc3<tm1Arge>,Igf1r<tm1Arge>/Igf1r<tm1Arge>
  http://metadb.riken.jp/0009728I129SSvEv129S1SvC57BL6JGpc3tm1ArgeGpc3tm1ArgeIgf1rtm1ArgeIgf1rtm1ArgeIgf1rtm1ArgeGpc3tm1Arge
• white spotting_Gpc3<tm1Arge>/Gpc3<+>
  http://metadb.riken.jp/0002938EI129SSvEv129S1SvorI129S1SvC57BL6JGpc3tm1ArgeGpc3Gpc3tm1ArgeGpc3

class

http://purl.org/net/cito/citesAsAuthority

• Gpc3<tm1Arge>
  http://metadb.riken.jp/db/mgi_rdf/MGI:2657134