Brent. McCright, et.al., A mouse model of Alagille syndrome: Notch2 as a genetic modifier of Jag1 haploinsufficiency., Development (Cambridge, England), 2002, 129

http://rdf.ncbi.nlm.nih.gov/pubmed/11861489

Brent. McCright, et.al., A mouse model of Alagille syndrome: Notch2 as a genetic modifier of Jag1 haploinsufficiency., Development (Cambridge, England), 2002, 129

pubmed

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• abnormal liver morphology_Jag1<tm1Grid>/Jag1<+>,Notch2<tm1Grid>/Notch2<+>
  http://metadb.riken.jp/0000598I129S1SvC57BL6JJag1tm1GridJag1Notch2tm1GridNotch2Notch2Jag1Jag1tm1GridNotch2tm1Grid
• decreased renal glomerulus number_Jag1<tm1Grid>/Jag1<+>,Notch2<tm1Grid>/Notch2<+>
  http://metadb.riken.jp/0004505I129S1SvC57BL6JJag1tm1GridJag1Notch2tm1GridNotch2Notch2Jag1Jag1tm1GridNotch2tm1Grid
• kidney microaneurysm_Jag1<tm1Grid>/Jag1<+>,Notch2<tm1Grid>/Notch2<+>
  http://metadb.riken.jp/0010451I129S1SvC57BL6JJag1tm1GridJag1Notch2tm1GridNotch2Notch2Jag1Jag1tm1GridNotch2tm1Grid
• postnatal lethality, incomplete penetrance_Jag1<tm1Grid>/Jag1<+>,Notch2<tm1Grid>/Notch2<+>
  http://metadb.riken.jp/0011086I129S1SvC57BL6JJag1tm1GridJag1Notch2tm1GridNotch2Notch2Jag1Jag1tm1GridNotch2tm1Grid
• cholestasis_Jag1<tm1Grid>/Jag1<+>,Notch2<tm1Grid>/Notch2<+>
  http://metadb.riken.jp/0000610I129S1SvC57BL6JJag1tm1GridJag1Notch2tm1GridNotch2Notch2Jag1Jag1tm1GridNotch2tm1Grid
• increased circulating alanine transaminase level_Jag1<tm1Grid>/Jag1<+>,Notch2<tm1Grid>/Notch2<+>
  http://metadb.riken.jp/0002941I129S1SvC57BL6JJag1tm1GridJag1Notch2tm1GridNotch2Notch2Jag1Jag1tm1GridNotch2tm1Grid
• abnormal bile duct development_Notch2<tm1Grid>/Notch2<tm1Grid>
  http://metadb.riken.jp/0002929I129S1SvC57BL6JNotch2tm1GridNotch2tm1GridNotch2tm1Grid
• postnatal growth retardation_Jag1<tm1Grid>/Jag1<+>,Notch2<tm1Grid>/Notch2<+>
  http://metadb.riken.jp/0001732I129S1SvC57BL6JJag1tm1GridJag1Notch2tm1GridNotch2Notch2Jag1Jag1tm1GridNotch2tm1Grid
• overriding aortic valve_Jag1<tm1Grid>/Jag1<+>,Notch2<tm1Grid>/Notch2<+>
  http://metadb.riken.jp/0000273I129S1SvC57BL6JJag1tm1GridJag1Notch2tm1GridNotch2Notch2Jag1Jag1tm1GridNotch2tm1Grid
• increased blood urea nitrogen level_Jag1<tm1Grid>/Jag1<+>,Notch2<tm1Grid>/Notch2<+>
  http://metadb.riken.jp/0005565I129S1SvC57BL6JJag1tm1GridJag1Notch2tm1GridNotch2Notch2Jag1Jag1tm1GridNotch2tm1Grid
• pulmonary artery stenosis_Jag1<tm1Grid>/Jag1<+>,Notch2<tm1Grid>/Notch2<+>
  http://metadb.riken.jp/0010457I129S1SvC57BL6JJag1tm1GridJag1Notch2tm1GridNotch2Notch2Jag1Jag1tm1GridNotch2tm1Grid
• atrial septal defect_Jag1<tm1Grid>/Jag1<+>,Notch2<tm1Grid>/Notch2<+>
  http://metadb.riken.jp/0010403I129S1SvC57BL6JJag1tm1GridJag1Notch2tm1GridNotch2Notch2Jag1Jag1tm1GridNotch2tm1Grid
• ventricular septal defect_Jag1<tm1Grid>/Jag1<+>,Notch2<tm1Grid>/Notch2<+>
  http://metadb.riken.jp/0010402I129S1SvC57BL6JJag1tm1GridJag1Notch2tm1GridNotch2Notch2Jag1Jag1tm1GridNotch2tm1Grid
• ventricular hypoplasia_Jag1<tm1Grid>/Jag1<+>,Notch2<tm1Grid>/Notch2<+>
  http://metadb.riken.jp/0000279I129S1SvC57BL6JJag1tm1GridJag1Notch2tm1GridNotch2Notch2Jag1Jag1tm1GridNotch2tm1Grid
• abnormal anterior eye segment morphology_Jag1<tm1Grid>/Jag1<+>,Notch2<tm1Grid>/Notch2<+>
  http://metadb.riken.jp/0005193I129S1SvC57BL6JJag1tm1GridJag1Notch2tm1GridNotch2Notch2Jag1Jag1tm1GridNotch2tm1Grid
• increased circulating alkaline phosphatase level_Jag1<tm1Grid>/Jag1<+>,Notch2<tm1Grid>/Notch2<+>
  http://metadb.riken.jp/0002968I129S1SvC57BL6JJag1tm1GridJag1Notch2tm1GridNotch2Notch2Jag1Jag1tm1GridNotch2tm1Grid
• jaundice_Jag1<tm1Grid>/Jag1<+>,Notch2<tm1Grid>/Notch2<+>
  http://metadb.riken.jp/0000611I129S1SvC57BL6JJag1tm1GridJag1Notch2tm1GridNotch2Notch2Jag1Jag1tm1GridNotch2tm1Grid
• abnormal bile duct development_Jag1<tm1Grid>/Jag1<+>,Notch2<tm1Grid>/Notch2<+>
  http://metadb.riken.jp/0002929I129S1SvC57BL6JJag1tm1GridJag1Notch2tm1GridNotch2Notch2Jag1Jag1tm1GridNotch2tm1Grid