Shaw-Yung. Shai, et.al., Cardiac myocyte-specific excision of the beta1 integrin gene results in myocardial fibrosis and cardiac failure., Circulation research, 2002, 90

http://rdf.ncbi.nlm.nih.gov/pubmed/11884376

Shaw-Yung. Shai, et.al., Cardiac myocyte-specific excision of the beta1 integrin gene results in myocardial fibrosis and cardiac failure., Circulation research, 2002, 90

pubmed

allele

http://purl.org/net/cito/citesAsAuthority

• Itgb1<tm1Ross>
  http://metadb.riken.jp/db/mgi_rdf/MGI:2656179

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• abnormal myocardial fiber morphology_Itgb1<tm1Ross>/Itgb1<tm1Ross>,Myl2<tm1(cre)Krc>/Myl2<+>
  http://metadb.riken.jp/0000278I129S1Sv129S4SvJae129X1SvJBlackSwissItgb1tm1RossItgb1tm1RossMyl2tm1creKrcMyl2Itgb1tm1RossMyl2Myl2tm1creKrc
• decreased ventricle muscle contractility_Itgb1<tm1Ross>/Itgb1<tm1Ross>,Myl2<tm1(cre)Krc>/Myl2<+>
  http://metadb.riken.jp/0005598I129S1Sv129S4SvJae129X1SvJBlackSwissItgb1tm1RossItgb1tm1RossMyl2tm1creKrcMyl2Itgb1tm1RossMyl2Myl2tm1creKrc
• dilated heart left ventricle_Itgb1<tm1Ross>/Itgb1<tm1Ross>,Myl2<tm1(cre)Krc>/Myl2<+>
  http://metadb.riken.jp/0002753I129S1Sv129S4SvJae129X1SvJBlackSwissItgb1tm1RossItgb1tm1RossMyl2tm1creKrcMyl2Itgb1tm1RossMyl2Myl2tm1creKrc
• pleural effusion_Itgb1<tm1Ross>/Itgb1<tm1Ross>,Myl2<tm1(cre)Krc>/Myl2<+>
  http://metadb.riken.jp/0010334I129S1Sv129S4SvJae129X1SvJBlackSwissItgb1tm1RossItgb1tm1RossMyl2tm1creKrcMyl2Itgb1tm1RossMyl2Myl2tm1creKrc
• increased response of heart to induced stress_Itgb1<tm1Ross>/Itgb1<tm1Ross>,Myl2<tm1(cre)Krc>/Myl2<+>
  http://metadb.riken.jp/0004485I129S1Sv129S4SvJae129X1SvJBlackSwissItgb1tm1RossItgb1tm1RossMyl2tm1creKrcMyl2Itgb1tm1RossMyl2Myl2tm1creKrc
• thick ventricular wall_Itgb1<tm1Ross>/Itgb1<tm1Ross>,Myl2<tm1(cre)Krc>/Myl2<+>
  http://metadb.riken.jp/0002953I129S1Sv129S4SvJae129X1SvJBlackSwissItgb1tm1RossItgb1tm1RossMyl2tm1creKrcMyl2Itgb1tm1RossMyl2Myl2tm1creKrc
• dilated heart_Itgb1<tm1Ross>/Itgb1<tm1Ross>,Myl2<tm1(cre)Krc>/Myl2<+>
  http://metadb.riken.jp/0004937I129S1Sv129S4SvJae129X1SvJBlackSwissItgb1tm1RossItgb1tm1RossMyl2tm1creKrcMyl2Itgb1tm1RossMyl2Myl2tm1creKrc
• abnormal heart ventricle morphology_Itgb1<tm1Ross>/Itgb1<tm1Ross>,Myl2<tm1(cre)Krc>/Myl2<+>
  http://metadb.riken.jp/0005294I129S1Sv129S4SvJae129X1SvJBlackSwissItgb1tm1RossItgb1tm1RossMyl2tm1creKrcMyl2Itgb1tm1RossMyl2Myl2tm1creKrc
• dilated cardiomyopathy_Itgb1<tm1Ross>/Itgb1<tm1Ross>,Myl2<tm1(cre)Krc>/Myl2<+>
  http://metadb.riken.jp/0002795I129S1Sv129S4SvJae129X1SvJBlackSwissItgb1tm1RossItgb1tm1RossMyl2tm1creKrcMyl2Itgb1tm1RossMyl2Myl2tm1creKrc
• abnormal cardiac cell glucose uptake_Itgb1<tm1Ross>/Itgb1<tm1Ross>,Myl2<tm1(cre)Krc>/Myl2<+>
  http://metadb.riken.jp/0004039I129S1Sv129S4SvJae129X1SvJBlackSwissItgb1tm1RossItgb1tm1RossMyl2tm1creKrcMyl2Itgb1tm1RossMyl2Myl2tm1creKrc
• abnormal atrial thrombosis_Itgb1<tm1Ross>/Itgb1<tm1Ross>,Myl2<tm1(cre)Krc>/Myl2<+>
  http://metadb.riken.jp/0001855I129S1Sv129S4SvJae129X1SvJBlackSwissItgb1tm1RossItgb1tm1RossMyl2tm1creKrcMyl2Itgb1tm1RossMyl2Myl2tm1creKrc
• liver vascular congestion_Itgb1<tm1Ross>/Itgb1<tm1Ross>,Myl2<tm1(cre)Krc>/Myl2<+>
  http://metadb.riken.jp/0010019I129S1Sv129S4SvJae129X1SvJBlackSwissItgb1tm1RossItgb1tm1RossMyl2tm1creKrcMyl2Itgb1tm1RossMyl2Myl2tm1creKrc
• increased sensitivity to induced morbidity/mortality_Itgb1<tm1Ross>/Itgb1<tm1Ross>,Myl2<tm1(cre)Krc>/Myl2<+>
  http://metadb.riken.jp/0009763I129S1Sv129S4SvJae129X1SvJBlackSwissItgb1tm1RossItgb1tm1RossMyl2tm1creKrcMyl2Itgb1tm1RossMyl2Myl2tm1creKrc
• abnormal myocardium layer morphology_Itgb1<tm1Ross>/Itgb1<tm1Ross>,Myl2<tm1(cre)Krc>/Myl2<+>
  http://metadb.riken.jp/0005329I129S1Sv129S4SvJae129X1SvJBlackSwissItgb1tm1RossItgb1tm1RossMyl2tm1creKrcMyl2Itgb1tm1RossMyl2Myl2tm1creKrc
• enlarged heart atrium_Itgb1<tm1Ross>/Itgb1<tm1Ross>,Myl2<tm1(cre)Krc>/Myl2<+>
  http://metadb.riken.jp/0008725I129S1Sv129S4SvJae129X1SvJBlackSwissItgb1tm1RossItgb1tm1RossMyl2tm1creKrcMyl2Itgb1tm1RossMyl2Myl2tm1creKrc
• cardiac fibrosis_Itgb1<tm1Ross>/Itgb1<tm1Ross>,Myl2<tm1(cre)Krc>/Myl2<+>
  http://metadb.riken.jp/0003141I129S1Sv129S4SvJae129X1SvJBlackSwissItgb1tm1RossItgb1tm1RossMyl2tm1creKrcMyl2Itgb1tm1RossMyl2Myl2tm1creKrc
• congestive heart failure_Itgb1<tm1Ross>/Itgb1<tm1Ross>,Myl2<tm1(cre)Krc>/Myl2<+>
  http://metadb.riken.jp/0006138I129S1Sv129S4SvJae129X1SvJBlackSwissItgb1tm1RossItgb1tm1RossMyl2tm1creKrcMyl2Itgb1tm1RossMyl2Myl2tm1creKrc
• abnormal cardiac muscle relaxation_Itgb1<tm1Ross>/Itgb1<tm1Ross>,Myl2<tm1(cre)Krc>/Myl2<+>
  http://metadb.riken.jp/0004084I129S1Sv129S4SvJae129X1SvJBlackSwissItgb1tm1RossItgb1tm1RossMyl2tm1creKrcMyl2Itgb1tm1RossMyl2Myl2tm1creKrc
• dilated heart right ventricle_Itgb1<tm1Ross>/Itgb1<tm1Ross>,Myl2<tm1(cre)Krc>/Myl2<+>
  http://metadb.riken.jp/0002754I129S1Sv129S4SvJae129X1SvJBlackSwissItgb1tm1RossItgb1tm1RossMyl2tm1creKrcMyl2Itgb1tm1RossMyl2Myl2tm1creKrc

class

http://purl.org/net/cito/citesAsAuthority

• Itgb1<tm1Ross>
  http://metadb.riken.jp/db/mgi_rdf/MGI:2656179