Kenji. Tanigaki, et.al., Notch-RBP-J signaling is involved in cell fate determination of marginal zone B cells., Nature immunology, 2002, 3

http://rdf.ncbi.nlm.nih.gov/pubmed/11967543

Kenji. Tanigaki, et.al., Notch-RBP-J signaling is involved in cell fate determination of marginal zone B cells., Nature immunology, 2002, 3

pubmed

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• decreased marginal zone B cell number_Rbpj<tm1Hon>/Rbpj<tm1Hon>,Tg(Mx1-cre)1Cgn/0
  http://metadb.riken.jp/0008182I129P2OlaHsdC57BL6CBARbpjtm1HonRbpjtm1HonTgMx1cre1Cgn0Rbpjtm1HonTgMx1cre1Cgn
• increased follicular B cell number_Cd19<tm1(cre)Cgn>/Cd19<+>,Rbpj<tm1Hon>/Rbpj<tm1Hon>
  http://metadb.riken.jp/0008173I129P2OlaHsdC57BL6Cd19tm1creCgnCd19Rbpjtm1HonRbpjtm1HonRbpjtm1HonCd19tm1creCgnCd19
• increased susceptibility to bacterial infection_Cd19<tm1(cre)Cgn>/Cd19<+>,Rbpj<tm1Hon>/Rbpj<tm1Hon>
  http://metadb.riken.jp/0002412I129P2OlaHsdC57BL6Cd19tm1creCgnCd19Rbpjtm1HonRbpjtm1HonRbpjtm1HonCd19tm1creCgnCd19
• abnormal B cell differentiation_Cd19<tm1(cre)Cgn>/Cd19<+>,Rbpj<tm1Hon>/Rbpj<tm1Hon>
  http://metadb.riken.jp/0002144I129P2OlaHsdC57BL6Cd19tm1creCgnCd19Rbpjtm1HonRbpjtm1HonRbpjtm1HonCd19tm1creCgnCd19
• increased susceptibility to bacterial infection induced morbidity/mortality_Cd19<tm1(cre)Cgn>/Cd19<+>,Rbpj<tm1Hon>/Rbpj<tm1Hon>
  http://metadb.riken.jp/0009788I129P2OlaHsdC57BL6Cd19tm1creCgnCd19Rbpjtm1HonRbpjtm1HonRbpjtm1HonCd19tm1creCgnCd19
• increased IgG3 level_Cd19<tm1(cre)Cgn>/Cd19<+>,Rbpj<tm1Hon>/Rbpj<tm1Hon>
  http://metadb.riken.jp/0008502I129P2OlaHsdC57BL6Cd19tm1creCgnCd19Rbpjtm1HonRbpjtm1HonRbpjtm1HonCd19tm1creCgnCd19
• decreased marginal zone B cell number_Cd19<tm1(cre)Cgn>/Cd19<+>,Rbpj<tm1Hon>/Rbpj<tm1Hon>
  http://metadb.riken.jp/0008182I129P2OlaHsdC57BL6Cd19tm1creCgnCd19Rbpjtm1HonRbpjtm1HonRbpjtm1HonCd19tm1creCgnCd19

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• immune system phenotype in RBRC01071
  http://metadb.riken.jp/db/rikenbrc_mouse/Phenotype_1014918
• immune system phenotype in RBRC02104
  http://metadb.riken.jp/db/rikenbrc_mouse/Phenotype_1020364