Ilse. Dewachter, et.al., Neuronal deficiency of presenilin 1 inhibits amyloid plaque formation and corrects hippocampal long-term potentiation but not a cognitive defect of amyloid precursor protein [V717I] transgenic mice., The Journal of neuroscience : the official journal of the Society for Neuroscience, 2002, 22

http://rdf.ncbi.nlm.nih.gov/pubmed/11978821

Ilse. Dewachter, et.al., Neuronal deficiency of presenilin 1 inhibits amyloid plaque formation and corrects hippocampal long-term potentiation but not a cognitive defect of amyloid precursor protein [V717I] transgenic mice., The Journal of neuroscience : the official journal of the Society for Neuroscience, 2002, 22

pubmed

allele

http://purl.org/net/cito/citesAsAuthority

• Tg(Thy1-cre)1Vln
  http://metadb.riken.jp/db/mgi_rdf/MGI:2684620
• Psen1<tm1Vln>
  http://metadb.riken.jp/db/mgi_rdf/MGI:2684616

class

http://purl.org/net/cito/citesAsAuthority

• Tg(Thy1-cre)1Vln
  http://metadb.riken.jp/db/mgi_rdf/MGI:2684620
• Psen1<tm1Vln>
  http://metadb.riken.jp/db/mgi_rdf/MGI:2684616

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• no abnormal phenotype detected_Psen1<tm1Vln>/Psen1<tm1Vln>
  http://metadb.riken.jp/0002169NSPsen1tm1VlnPsen1tm1VlnPsen1tm1Vln
• abnormal object recognition memory_Psen1<tm1Vln>/Psen1<tm1Vln>,Tg(Thy1-APPLon)2Vln/0,Tg(Thy1-cre)1Vln/0
  http://metadb.riken.jp/0001458IFVBNPsen1tm1VlnPsen1tm1VlnTgThy1APPLon2Vln0TgThy1cre1Vln0Psen1tm1VlnTgThy1cre1VlnTgThy1APPLon2Vln
• amyloid beta deposits_Psen1<tm1Vln>/Psen1<tm1Vln>,Tg(Thy1-cre)1Vln/0
  http://metadb.riken.jp/0003329IFVBNPsen1tm1VlnPsen1tm1VlnTgThy1cre1Vln0Psen1tm1VlnTgThy1cre1Vln
• amyloidosis_Tg(Thy1-APPLon)2Vln/0
  http://metadb.riken.jp/0000604IFVBNTgThy1APPLon2Vln0TgThy1APPLon2Vln
• abnormal long term potentiation_Psen1<tm1Vln>/Psen1<tm1Vln>,Tg(Thy1-cre)1Vln/0
  http://metadb.riken.jp/0002207IFVBNPsen1tm1VlnPsen1tm1VlnTgThy1cre1Vln0Psen1tm1VlnTgThy1cre1Vln
• reduced long term potentiation_Tg(Thy1-APPLon)2Vln/0
  http://metadb.riken.jp/0001473IFVBNTgThy1APPLon2Vln0TgThy1APPLon2Vln
• abnormal long term potentiation_Psen1<tm1Vln>/Psen1<tm1Vln>,Tg(Thy1-APPLon)2Vln/0,Tg(Thy1-cre)1Vln/0
  http://metadb.riken.jp/0002207IFVBNPsen1tm1VlnPsen1tm1VlnTgThy1APPLon2Vln0TgThy1cre1Vln0Psen1tm1VlnTgThy1cre1VlnTgThy1APPLon2Vln