Michael K. Lee, et.al., Human alpha-synuclein-harboring familial Parkinson's disease-linked Ala-53 --> Thr mutation causes neurodegenerative disease with alpha-synuclein aggregation in transgenic mice., Proceedings of the National Academy of Sciences of the United States of America, 2002, 99

http://rdf.ncbi.nlm.nih.gov/pubmed/12084935

Michael K. Lee, et.al., Human alpha-synuclein-harboring familial Parkinson's disease-linked Ala-53 --> Thr mutation causes neurodegenerative disease with alpha-synuclein aggregation in transgenic mice., Proceedings of the National Academy of Sciences of the United States of America, 2002, 99

pubmed

allele

http://purl.org/net/cito/citesAsAuthority

• Tg(Prnp-SNCA*A30P)3Dpr
  http://metadb.riken.jp/db/mgi_rdf/MGI:4942281
• Tg(Prnp-SNCA)22Dpr
  http://metadb.riken.jp/db/mgi_rdf/MGI:3530087
• Tg(Prnp-SNCA*A53T)25Mkle
  http://metadb.riken.jp/db/mgi_rdf/MGI:4942280
• Tg(Prnp-SNCA*A53T)23Mkle
  http://metadb.riken.jp/db/mgi_rdf/MGI:3530127
• Tg(Prnp-SNCA*A30P)2Dpr
  http://metadb.riken.jp/db/mgi_rdf/MGI:3530128

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• abnormal motor capabilities/coordination/movement_Tg(Prnp-SNCA*A53T)25Mkle/0
  http://metadb.riken.jp/0002066IC3HHeJC57BL6JTgPrnpSNCAA53T25Mkle0TgPrnpSNCAA53T25Mkle
• neuronal intranuclear inclusions_Tg(Prnp-SNCA*A53T)23Mkle/0
  http://metadb.riken.jp/0004191IC3HHeJC57BL6JTgPrnpSNCAA53T23Mkle0TgPrnpSNCAA53T23Mkle
• abnormal spinal cord morphology_Tg(Prnp-SNCA*A53T)23Mkle/0
  http://metadb.riken.jp/0000955IC3HHeJC57BL6JTgPrnpSNCAA53T23Mkle0TgPrnpSNCAA53T23Mkle
• neurodegeneration_Tg(Prnp-SNCA*A53T)25Mkle/0
  http://metadb.riken.jp/0002229IC3HHeJC57BL6JTgPrnpSNCAA53T25Mkle0TgPrnpSNCAA53T25Mkle
• neurodegeneration_Tg(Prnp-SNCA*A53T)23Mkle/0
  http://metadb.riken.jp/0002229IC3HHeJC57BL6JTgPrnpSNCAA53T23Mkle0TgPrnpSNCAA53T23Mkle
• premature death_Tg(Prnp-SNCA*A53T)25Mkle/0
  http://metadb.riken.jp/0002083IC3HHeJC57BL6JTgPrnpSNCAA53T25Mkle0TgPrnpSNCAA53T25Mkle
• premature death_Tg(Prnp-SNCA*A53T)23Mkle/0
  http://metadb.riken.jp/0002083IC3HHeJC57BL6JTgPrnpSNCAA53T23Mkle0TgPrnpSNCAA53T23Mkle
• impaired righting response_Tg(Prnp-SNCA*A53T)25Mkle/0
  http://metadb.riken.jp/0001523IC3HHeJC57BL6JTgPrnpSNCAA53T25Mkle0TgPrnpSNCAA53T25Mkle
• paralysis_Tg(Prnp-SNCA*A53T)23Mkle/0
  http://metadb.riken.jp/0000753IC3HHeJC57BL6JTgPrnpSNCAA53T23Mkle0TgPrnpSNCAA53T23Mkle
• astrocytosis_Tg(Prnp-SNCA*A53T)25Mkle/0
  http://metadb.riken.jp/0003354IC3HHeJC57BL6JTgPrnpSNCAA53T25Mkle0TgPrnpSNCAA53T25Mkle
• abnormal nervous system morphology_Tg(Prnp-SNCA*A53T)25Mkle/0
  http://metadb.riken.jp/0003632IC3HHeJC57BL6JTgPrnpSNCAA53T25Mkle0TgPrnpSNCAA53T25Mkle
• astrocytosis_Tg(Prnp-SNCA*A53T)23Mkle/0
  http://metadb.riken.jp/0003354IC3HHeJC57BL6JTgPrnpSNCAA53T23Mkle0TgPrnpSNCAA53T23Mkle
• impaired righting response_Tg(Prnp-SNCA*A53T)23Mkle/0
  http://metadb.riken.jp/0001523IC3HHeJC57BL6JTgPrnpSNCAA53T23Mkle0TgPrnpSNCAA53T23Mkle
• dystonia_Tg(Prnp-SNCA*A53T)23Mkle/0
  http://metadb.riken.jp/0005323IC3HHeJC57BL6JTgPrnpSNCAA53T23Mkle0TgPrnpSNCAA53T23Mkle
• abnormal motor capabilities/coordination/movement_Tg(Prnp-SNCA*A53T)23Mkle/0
  http://metadb.riken.jp/0002066IC3HHeJC57BL6JTgPrnpSNCAA53T23Mkle0TgPrnpSNCAA53T23Mkle
• dystonia_Tg(Prnp-SNCA*A53T)25Mkle/0
  http://metadb.riken.jp/0005323IC3HHeJC57BL6JTgPrnpSNCAA53T25Mkle0TgPrnpSNCAA53T25Mkle
• ataxia_Tg(Prnp-SNCA*A53T)25Mkle/0
  http://metadb.riken.jp/0001393IC3HHeJC57BL6JTgPrnpSNCAA53T25Mkle0TgPrnpSNCAA53T25Mkle
• bradykinesia_Tg(Prnp-SNCA*A53T)23Mkle/0
  http://metadb.riken.jp/0005156IC3HHeJC57BL6JTgPrnpSNCAA53T23Mkle0TgPrnpSNCAA53T23Mkle
• ataxia_Tg(Prnp-SNCA*A53T)23Mkle/0
  http://metadb.riken.jp/0001393IC3HHeJC57BL6JTgPrnpSNCAA53T23Mkle0TgPrnpSNCAA53T23Mkle
• abnormal neuron morphology_Tg(Prnp-SNCA*A53T)25Mkle/0
  http://metadb.riken.jp/0002882IC3HHeJC57BL6JTgPrnpSNCAA53T25Mkle0TgPrnpSNCAA53T25Mkle
• neuronal intranuclear inclusions_Tg(Prnp-SNCA*A53T)25Mkle/0
  http://metadb.riken.jp/0004191IC3HHeJC57BL6JTgPrnpSNCAA53T25Mkle0TgPrnpSNCAA53T25Mkle
• abnormal neuron morphology_Tg(Prnp-SNCA*A53T)23Mkle/0
  http://metadb.riken.jp/0002882IC3HHeJC57BL6JTgPrnpSNCAA53T23Mkle0TgPrnpSNCAA53T23Mkle
• abnormal nervous system morphology_Tg(Prnp-SNCA*A53T)23Mkle/0
  http://metadb.riken.jp/0003632IC3HHeJC57BL6JTgPrnpSNCAA53T23Mkle0TgPrnpSNCAA53T23Mkle
• paralysis_Tg(Prnp-SNCA*A53T)25Mkle/0
  http://metadb.riken.jp/0000753IC3HHeJC57BL6JTgPrnpSNCAA53T25Mkle0TgPrnpSNCAA53T25Mkle
• abnormal spinal cord morphology_Tg(Prnp-SNCA*A53T)25Mkle/0
  http://metadb.riken.jp/0000955IC3HHeJC57BL6JTgPrnpSNCAA53T25Mkle0TgPrnpSNCAA53T25Mkle
• bradykinesia_Tg(Prnp-SNCA*A53T)25Mkle/0
  http://metadb.riken.jp/0005156IC3HHeJC57BL6JTgPrnpSNCAA53T25Mkle0TgPrnpSNCAA53T25Mkle

class

http://purl.org/net/cito/citesAsAuthority

• Tg(Prnp-SNCA*A30P)3Dpr
  http://metadb.riken.jp/db/mgi_rdf/MGI:4942281
• Tg(Prnp-SNCA)22Dpr
  http://metadb.riken.jp/db/mgi_rdf/MGI:3530087
• Tg(Prnp-SNCA*A53T)25Mkle
  http://metadb.riken.jp/db/mgi_rdf/MGI:4942280
• Tg(Prnp-SNCA*A53T)23Mkle
  http://metadb.riken.jp/db/mgi_rdf/MGI:3530127
• Tg(Prnp-SNCA*A30P)2Dpr
  http://metadb.riken.jp/db/mgi_rdf/MGI:3530128