Masakazu. Higuchi, et.al., Expression of a conditional AML1-ETO oncogene bypasses embryonic lethality and establishes a murine model of human t(8;21) acute myeloid leukemia., Cancer cell, 2002, 1

http://rdf.ncbi.nlm.nih.gov/pubmed/12086889

Masakazu. Higuchi, et.al., Expression of a conditional AML1-ETO oncogene bypasses embryonic lethality and establishes a murine model of human t(8;21) acute myeloid leukemia., Cancer cell, 2002, 1

pubmed

allele

http://purl.org/net/cito/citesAsAuthority

• Runx1<tm3Dow>
  http://metadb.riken.jp/db/mgi_rdf/MGI:2387301

class

http://purl.org/net/cito/citesAsAuthority

• Runx1<tm3Dow>
  http://metadb.riken.jp/db/mgi_rdf/MGI:2387301

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• increased acute promyelocytic leukemia incidence_Runx1<tm3Dow>/Runx1<+>,Tg(Mx1-cre)1Cgn/0
  http://metadb.riken.jp/0004049IC57BL6CBARunx1tm3DowRunx1TgMx1cre1Cgn0Runx1tm3DowTgMx1cre1CgnRunx1
• increased tumor incidence_Runx1<tm3Dow>/Runx1<+>,Tg(Mx1-cre)1Cgn/0
  http://metadb.riken.jp/0002020IC57BL6CBARunx1tm3DowRunx1TgMx1cre1Cgn0Runx1tm3DowTgMx1cre1CgnRunx1
• increased T cell derived lymphoma incidence_Runx1<tm3Dow>/Runx1<+>,Tg(Mx1-cre)1Cgn/0
  http://metadb.riken.jp/0002024IC57BL6CBARunx1tm3DowRunx1TgMx1cre1Cgn0Runx1tm3DowTgMx1cre1CgnRunx1
• abnormal hematopoietic system morphology/development_Runx1<tm3Dow>/Runx1<+>,Tg(Mx1-cre)1Cgn/0
  http://metadb.riken.jp/0002396IC57BL6CBARunx1tm3DowRunx1TgMx1cre1Cgn0Runx1tm3DowTgMx1cre1CgnRunx1
• premature death_Runx1<tm3Dow>/Runx1<+>,Tg(Mx1-cre)1Cgn/0
  http://metadb.riken.jp/0002083IC57BL6CBARunx1tm3DowRunx1TgMx1cre1Cgn0Runx1tm3DowTgMx1cre1CgnRunx1
• increased sarcoma incidence_Runx1<tm3Dow>/Runx1<+>,Tg(Mx1-cre)1Cgn/0
  http://metadb.riken.jp/0002032IC57BL6CBARunx1tm3DowRunx1TgMx1cre1Cgn0Runx1tm3DowTgMx1cre1CgnRunx1
• abnormal cell physiology_Runx1<tm3Dow>/Runx1<+>,Tg(Mx1-cre)1Cgn/0
  http://metadb.riken.jp/0005621IC57BL6CBARunx1tm3DowRunx1TgMx1cre1Cgn0Runx1tm3DowTgMx1cre1CgnRunx1