Klaus. Okkenhaug, et.al., Impaired B and T cell antigen receptor signaling in p110delta PI 3-kinase mutant mice., Science (New York, N.Y.), 2002, 297

http://rdf.ncbi.nlm.nih.gov/pubmed/12130661

Klaus. Okkenhaug, et.al., Impaired B and T cell antigen receptor signaling in p110delta PI 3-kinase mutant mice., Science (New York, N.Y.), 2002, 297

pubmed

allele

http://purl.org/net/cito/citesAsAuthority

• Pik3cd<tm1Bvan>
  http://metadb.riken.jp/db/mgi_rdf/MGI:2385595
• Pik3cd<tm1.1Bvan>
  http://metadb.riken.jp/db/mgi_rdf/MGI:2385596

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• decreased B-1 B cell number_Pik3cd<tm1.1Bvan>/Pik3cd<tm1.1Bvan>
  http://metadb.riken.jp/0004978I129P2OlaHsdBALBcPik3cdtm11BvanPik3cdtm11BvanPik3cdtm11Bvan
• spleen hypoplasia_Pik3cd<tm1.1Bvan>/Pik3cd<tm1.1Bvan>
  http://metadb.riken.jp/0000694I129P2OlaHsdBALBcPik3cdtm11BvanPik3cdtm11BvanPik3cdtm11Bvan
• decreased IgM level_Pik3cd<tm1.1Bvan>/Pik3cd<tm1.1Bvan>
  http://metadb.riken.jp/0001806I129P2OlaHsdBALBcPik3cdtm11BvanPik3cdtm11BvanPik3cdtm11Bvan
• abnormal intestinal mucosa morphology_Pik3cd<tm1.1Bvan>/Pik3cd<tm1.1Bvan>
  http://metadb.riken.jp/0000511I129P2OlaHsdBALBcPik3cdtm11BvanPik3cdtm11BvanPik3cdtm11Bvan
• absent spleen germinal center_Pik3cd<tm1.1Bvan>/Pik3cd<tm1.1Bvan>
  http://metadb.riken.jp/0008474I129P2OlaHsdBALBcPik3cdtm11BvanPik3cdtm11BvanPik3cdtm11Bvan
• decreased immunoglobulin level_Pik3cd<tm1.1Bvan>/Pik3cd<tm1.1Bvan>
  http://metadb.riken.jp/0002460I129P2OlaHsdBALBcPik3cdtm11BvanPik3cdtm11BvanPik3cdtm11Bvan
• increased neutrophil cell number_Pik3cd<tm1.1Bvan>/Pik3cd<tm1.1Bvan>
  http://metadb.riken.jp/0000219I129P2OlaHsdBALBcPik3cdtm11BvanPik3cdtm11BvanPik3cdtm11Bvan
• crypts of Lieberkuhn abscesses_Pik3cd<tm1.1Bvan>/Pik3cd<tm1.1Bvan>
  http://metadb.riken.jp/0000491I129P2OlaHsdBALBcPik3cdtm11BvanPik3cdtm11BvanPik3cdtm11Bvan
• intestinal inflammation_Pik3cd<tm1.1Bvan>/Pik3cd<tm1.1Bvan>
  http://metadb.riken.jp/0001858I129P2OlaHsdBALBcPik3cdtm11BvanPik3cdtm11BvanPik3cdtm11Bvan
• decreased IgA level_Pik3cd<tm1.1Bvan>/Pik3cd<tm1.1Bvan>
  http://metadb.riken.jp/0001807I129P2OlaHsdBALBcPik3cdtm11BvanPik3cdtm11BvanPik3cdtm11Bvan
• abnormal intestinal epithelium morphology_Pik3cd<tm1.1Bvan>/Pik3cd<tm1.1Bvan>
  http://metadb.riken.jp/0000488I129P2OlaHsdBALBcPik3cdtm11BvanPik3cdtm11BvanPik3cdtm11Bvan
• abnormal Peyer's patch germinal center morphology_Pik3cd<tm1.1Bvan>/Pik3cd<tm1.1Bvan>
  http://metadb.riken.jp/0002391I129P2OlaHsdBALBcPik3cdtm11BvanPik3cdtm11BvanPik3cdtm11Bvan
• abnormal B cell differentiation_Pik3cd<tm1.1Bvan>/Pik3cd<tm1.1Bvan>
  http://metadb.riken.jp/0002144I129P2OlaHsdBALBcPik3cdtm11BvanPik3cdtm11BvanPik3cdtm11Bvan

class

http://purl.org/net/cito/citesAsAuthority

• Pik3cd<tm1Bvan>
  http://metadb.riken.jp/db/mgi_rdf/MGI:2385595
• Pik3cd<tm1.1Bvan>
  http://metadb.riken.jp/db/mgi_rdf/MGI:2385596