Mei. Zhang, et.al., Osteoblast-specific knockout of the insulin-like growth factor (IGF) receptor gene reveals an essential role of IGF signaling in bone matrix mineralization., The Journal of biological chemistry, 2002, 277

http://rdf.ncbi.nlm.nih.gov/pubmed/12215457

Mei. Zhang, et.al., Osteoblast-specific knockout of the insulin-like growth factor (IGF) receptor gene reveals an essential role of IGF signaling in bone matrix mineralization., The Journal of biological chemistry, 2002, 277

pubmed

allele

http://purl.org/net/cito/citesAsAuthority

• Tg(BGLAP-cre)1Clem
  http://metadb.riken.jp/db/mgi_rdf/MGI:2446069

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• abnormal skeleton physiology_Igf1r<tm2Arge>/Igf1r<tm2Arge>,Tg(BGLAP-cre)1Clem/0
  http://metadb.riken.jp/0001533I129FVBNIgf1rtm2ArgeIgf1rtm2ArgeTgBGLAPcre1Clem0TgBGLAPcre1ClemIgf1rtm2Arge
• abnormal skeleton morphology_Igf1r<tm2Arge>/Igf1r<tm2Arge>,Tg(BGLAP-cre)1Clem/0
  http://metadb.riken.jp/0005508I129FVBNIgf1rtm2ArgeIgf1rtm2ArgeTgBGLAPcre1Clem0TgBGLAPcre1ClemIgf1rtm2Arge
• decreased trabecular bone volume_Igf1r<tm2Arge>/Igf1r<tm2Arge>,Tg(BGLAP-cre)1Clem/0
  http://metadb.riken.jp/0010879I129FVBNIgf1rtm2ArgeIgf1rtm2ArgeTgBGLAPcre1Clem0TgBGLAPcre1ClemIgf1rtm2Arge
• abnormal trabecular bone morphology_Igf1r<tm2Arge>/Igf1r<tm2Arge>,Tg(BGLAP-cre)1Clem/0
  http://metadb.riken.jp/0000130I129FVBNIgf1rtm2ArgeIgf1rtm2ArgeTgBGLAPcre1Clem0TgBGLAPcre1ClemIgf1rtm2Arge
• decreased osteoclast cell number_Igf1r<tm2Arge>/Igf1r<tm2Arge>,Tg(BGLAP-cre)1Clem/0
  http://metadb.riken.jp/0004985I129FVBNIgf1rtm2ArgeIgf1rtm2ArgeTgBGLAPcre1Clem0TgBGLAPcre1ClemIgf1rtm2Arge
• decreased bone ossification_Igf1r<tm2Arge>/Igf1r<tm2Arge>,Tg(BGLAP-cre)1Clem/0
  http://metadb.riken.jp/0020040I129FVBNIgf1rtm2ArgeIgf1rtm2ArgeTgBGLAPcre1Clem0TgBGLAPcre1ClemIgf1rtm2Arge
• decreased bone trabecula number_Igf1r<tm2Arge>/Igf1r<tm2Arge>,Tg(BGLAP-cre)1Clem/0
  http://metadb.riken.jp/0010869I129FVBNIgf1rtm2ArgeIgf1rtm2ArgeTgBGLAPcre1Clem0TgBGLAPcre1ClemIgf1rtm2Arge
• abnormal osteoblast physiology_Igf1r<tm2Arge>/Igf1r<tm2Arge>,Tg(BGLAP-cre)1Clem/0
  http://metadb.riken.jp/0005006I129FVBNIgf1rtm2ArgeIgf1rtm2ArgeTgBGLAPcre1Clem0TgBGLAPcre1ClemIgf1rtm2Arge
• abnormal neurocranium morphology_Igf1r<tm2Arge>/Igf1r<tm2Arge>,Tg(BGLAP-cre)1Clem/0
  http://metadb.riken.jp/0000074I129FVBNIgf1rtm2ArgeIgf1rtm2ArgeTgBGLAPcre1Clem0TgBGLAPcre1ClemIgf1rtm2Arge
• decreased bone mineralization_Igf1r<tm2Arge>/Igf1r<tm2Arge>,Tg(BGLAP-cre)1Clem/0
  http://metadb.riken.jp/0020137I129FVBNIgf1rtm2ArgeIgf1rtm2ArgeTgBGLAPcre1Clem0TgBGLAPcre1ClemIgf1rtm2Arge
• decreased trabecular bone thickness_Igf1r<tm2Arge>/Igf1r<tm2Arge>,Tg(BGLAP-cre)1Clem/0
  http://metadb.riken.jp/0009346I129FVBNIgf1rtm2ArgeIgf1rtm2ArgeTgBGLAPcre1Clem0TgBGLAPcre1ClemIgf1rtm2Arge
• abnormal osteoclast physiology_Igf1r<tm2Arge>/Igf1r<tm2Arge>,Tg(BGLAP-cre)1Clem/0
  http://metadb.riken.jp/0001541I129FVBNIgf1rtm2ArgeIgf1rtm2ArgeTgBGLAPcre1Clem0TgBGLAPcre1ClemIgf1rtm2Arge
• decreased osteoblast cell number_Igf1r<tm2Arge>/Igf1r<tm2Arge>,Tg(BGLAP-cre)1Clem/0
  http://metadb.riken.jp/0004989I129FVBNIgf1rtm2ArgeIgf1rtm2ArgeTgBGLAPcre1Clem0TgBGLAPcre1ClemIgf1rtm2Arge

class

http://purl.org/net/cito/citesAsAuthority

• Tg(BGLAP-cre)1Clem
  http://metadb.riken.jp/db/mgi_rdf/MGI:2446069