Alexander Yu. Nikitin, et.al., Cell lineage-specific effects associated with multiple deficiencies of tumor susceptibility genes in Msh2(-/-)Rb(+/-) mice., Cancer research, 2002, 62

http://rdf.ncbi.nlm.nih.gov/pubmed/12234974

Alexander Yu. Nikitin, et.al., Cell lineage-specific effects associated with multiple deficiencies of tumor susceptibility genes in Msh2(-/-)Rb(+/-) mice., Cancer research, 2002, 62

pubmed

allele

http://purl.org/net/cito/citesAsAuthority

• Msh2<tm1Whl>
  http://metadb.riken.jp/db/mgi_rdf/MGI:2387935

class

http://purl.org/net/cito/citesAsAuthority

• Msh2<tm1Whl>
  http://metadb.riken.jp/db/mgi_rdf/MGI:2387935

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• increased pheochromocytoma incidence_Rb1<tm1Brd>/Rb1<+>
  http://metadb.riken.jp/0002050I129P2OlaHsd129S7SvEvBrdC57BL6JRb1tm1BrdRb1Rb1Rb1tm1Brd
• abnormal definitive hematopoiesis_Msh2<tm1Whl>/Msh2<tm1Whl>,Rb1<tm1Brd>/Rb1<tm1Brd>
  http://metadb.riken.jp/0002123I129P2OlaHsd129S7SvEvBrdC57BL6JMsh2tm1WhlMsh2tm1WhlRb1tm1BrdRb1tm1BrdRb1tm1BrdMsh2tm1Whl
• abnormal tumor morphology_Msh2<tm1Whl>/Msh2<tm1Whl>
  http://metadb.riken.jp/0003448I129P2OlaHsdC57BL6JMsh2tm1WhlMsh2tm1WhlMsh2tm1Whl
• increased pituitary melanotroph tumor incidence_Msh2<tm1Whl>/Msh2<tm1Whl>,Rb1<tm1Brd>/Rb1<+>
  http://metadb.riken.jp/0010351I129P2OlaHsd129S7SvEvBrdC57BL6JMsh2tm1WhlMsh2tm1WhlRb1tm1BrdRb1Msh2tm1WhlRb1tm1BrdRb1
• abnormal tumor morphology_Msh2<tm1Whl>/Msh2<tm1Whl>,Rb1<tm1Brd>/Rb1<+>
  http://metadb.riken.jp/0003448I129P2OlaHsd129S7SvEvBrdC57BL6JMsh2tm1WhlMsh2tm1WhlRb1tm1BrdRb1Msh2tm1WhlRb1tm1BrdRb1
• increased tumor incidence_Msh2<tm1Whl>/Msh2<tm1Whl>,Rb1<tm1Brd>/Rb1<+>
  http://metadb.riken.jp/0002020I129P2OlaHsd129S7SvEvBrdC57BL6JMsh2tm1WhlMsh2tm1WhlRb1tm1BrdRb1Msh2tm1WhlRb1tm1BrdRb1
• increased pheochromocytoma incidence_Msh2<tm1Whl>/Msh2<tm1Whl>,Rb1<tm1Brd>/Rb1<+>
  http://metadb.riken.jp/0002050I129P2OlaHsd129S7SvEvBrdC57BL6JMsh2tm1WhlMsh2tm1WhlRb1tm1BrdRb1Msh2tm1WhlRb1tm1BrdRb1
• premature death_Msh2<tm1Whl>/Msh2<tm1Whl>
  http://metadb.riken.jp/0002083I129P2OlaHsdC57BL6JMsh2tm1WhlMsh2tm1WhlMsh2tm1Whl
• increased skin tumor incidence_Msh2<tm1Whl>/Msh2<tm1Whl>
  http://metadb.riken.jp/0010300I129P2OlaHsdC57BL6JMsh2tm1WhlMsh2tm1WhlMsh2tm1Whl
• increased lymphoblastic lymphoma incidence_Msh2<tm1Whl>/Msh2<tm1Whl>
  http://metadb.riken.jp/0009320I129P2OlaHsdC57BL6JMsh2tm1WhlMsh2tm1WhlMsh2tm1Whl
• increased pituitary adenohypophysis tumor incidence_Rb1<tm1Brd>/Rb1<+>
  http://metadb.riken.jp/0010350I129P2OlaHsd129S7SvEvBrdC57BL6JRb1tm1BrdRb1Rb1Rb1tm1Brd
• abnormal definitive hematopoiesis_Msh2<tm1Whl>/Msh2<tm1Whl>,Rb1<tm1Brd>/Rb1<+>
  http://metadb.riken.jp/0002123I129P2OlaHsd129S7SvEvBrdC57BL6JMsh2tm1WhlMsh2tm1WhlRb1tm1BrdRb1Msh2tm1WhlRb1tm1BrdRb1
• premature death_Rb1<tm1Brd>/Rb1<+>,Trp53<tm1Brd>/Trp53<+>
  http://metadb.riken.jp/0002083I129S7SvEvBrdC57BL6JRb1tm1BrdRb1Trp53tm1BrdTrp53Trp53tm1BrdTrp53Rb1tm1BrdRb1
• increased thyroid C-cell carcinoma incidence_Msh2<tm1Whl>/Msh2<tm1Whl>,Rb1<tm1Brd>/Rb1<+>
  http://metadb.riken.jp/0010345I129P2OlaHsd129S7SvEvBrdC57BL6JMsh2tm1WhlMsh2tm1WhlRb1tm1BrdRb1Msh2tm1WhlRb1tm1BrdRb1
• increased gastrointestinal tumor incidence_Msh2<tm1Whl>/Msh2<tm1Whl>,Rb1<tm1Brd>/Rb1<+>
  http://metadb.riken.jp/0010279I129P2OlaHsd129S7SvEvBrdC57BL6JMsh2tm1WhlMsh2tm1WhlRb1tm1BrdRb1Msh2tm1WhlRb1tm1BrdRb1
• increased gastrointestinal tumor incidence_Msh2<tm1Whl>/Msh2<tm1Whl>
  http://metadb.riken.jp/0010279I129P2OlaHsdC57BL6JMsh2tm1WhlMsh2tm1WhlMsh2tm1Whl
• increased skin tumor incidence_Msh2<tm1Whl>/Msh2<tm1Whl>,Rb1<tm1Brd>/Rb1<+>
  http://metadb.riken.jp/0010300I129P2OlaHsd129S7SvEvBrdC57BL6JMsh2tm1WhlMsh2tm1WhlRb1tm1BrdRb1Msh2tm1WhlRb1tm1BrdRb1
• increased pituitary adenohypophysis tumor incidence_Msh2<tm1Whl>/Msh2<tm1Whl>,Rb1<tm1Brd>/Rb1<+>
  http://metadb.riken.jp/0010350I129P2OlaHsd129S7SvEvBrdC57BL6JMsh2tm1WhlMsh2tm1WhlRb1tm1BrdRb1Msh2tm1WhlRb1tm1BrdRb1
• increased pituitary melanotroph tumor incidence_Rb1<tm1Brd>/Rb1<+>
  http://metadb.riken.jp/0010351I129P2OlaHsd129S7SvEvBrdC57BL6JRb1tm1BrdRb1Rb1Rb1tm1Brd
• increased lymphoblastic lymphoma incidence_Msh2<tm1Whl>/Msh2<tm1Whl>,Rb1<tm1Brd>/Rb1<+>
  http://metadb.riken.jp/0009320I129P2OlaHsd129S7SvEvBrdC57BL6JMsh2tm1WhlMsh2tm1WhlRb1tm1BrdRb1Msh2tm1WhlRb1tm1BrdRb1
• increased thyroid C-cell carcinoma incidence_Rb1<tm1Brd>/Rb1<+>
  http://metadb.riken.jp/0010345I129P2OlaHsd129S7SvEvBrdC57BL6JRb1tm1BrdRb1Rb1Rb1tm1Brd
• premature death_Msh2<tm1Whl>/Msh2<tm1Whl>,Rb1<tm1Brd>/Rb1<+>
  http://metadb.riken.jp/0002083I129P2OlaHsd129S7SvEvBrdC57BL6JMsh2tm1WhlMsh2tm1WhlRb1tm1BrdRb1Msh2tm1WhlRb1tm1BrdRb1
• increased squamous cell carcinoma incidence_Msh2<tm1Whl>/Msh2<tm1Whl>
  http://metadb.riken.jp/0004207I129P2OlaHsdC57BL6JMsh2tm1WhlMsh2tm1WhlMsh2tm1Whl