C Brian. Bai, et.al., Gli2, but not Gli1, is required for initial Shh signaling and ectopic activation of the Shh pathway., Development (Cambridge, England), 2002, 129

http://rdf.ncbi.nlm.nih.gov/pubmed/12361967

C Brian. Bai, et.al., Gli2, but not Gli1, is required for initial Shh signaling and ectopic activation of the Shh pathway., Development (Cambridge, England), 2002, 129

pubmed

allele

http://purl.org/net/cito/citesAsAuthority

• Gli1<tm2Alj>
  http://metadb.riken.jp/db/mgi_rdf/MGI:2449767
• Tg(TK-cre)1Alj
  http://metadb.riken.jp/db/mgi_rdf/MGI:4437924

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• small lung_Gli1<tm2Alj>/Gli1<+>,Gli2<tm1Alj>/Gli2<tm1Alj>
  http://metadb.riken.jp/0003641I129S1Sv129X1SvJBlackSwissSwissWebsterGli1tm2AljGli1Gli2tm1AljGli2tm1AljGli2tm1AljGli1tm2AljGli1
• abnormal lung morphology_Gli1<tm2Alj>/Gli1<tm2Alj>,Gli2<tm1Alj>/Gli2<tm1Alj>
  http://metadb.riken.jp/0001175I129SvBlackSwissSwissWebsterGli1tm2AljGli1tm2AljGli2tm1AljGli2tm1AljGli1tm2AljGli2tm1Alj
• abnormal brain development_Gli2<tm1Alj>/Gli2<tm1Alj>,Ptch1<tm1Mps>/Ptch1<tm1Mps>
  http://metadb.riken.jp/0000913I129S1Sv129X1SvJSwissWebsterGli2tm1AljGli2tm1AljPtch1tm1MpsPtch1tm1MpsPtch1tm1MpsGli2tm1Alj
• small lung_Gli1<tm2Alj>/Gli1<tm2Alj>,Gli2<tm1Alj>/Gli2<+>
  http://metadb.riken.jp/0003641I129SvBlackSwissSwissWebsterGli1tm2AljGli1tm2AljGli2tm1AljGli2Gli2tm1AljGli2Gli1tm2Alj
• increased motor neuron number_Gli2<tm1Alj>/Gli2<tm1Alj>,Ptch1<tm1Mps>/Ptch1<tm1Mps>
  http://metadb.riken.jp/0005192I129S1Sv129X1SvJSwissWebsterGli2tm1AljGli2tm1AljPtch1tm1MpsPtch1tm1MpsPtch1tm1MpsGli2tm1Alj
• embryonic lethality during organogenesis, complete penetrance_Gli1<tm1Alj>/Gli1<tm1Alj>,Ptch1<tm1Mps>/Ptch1<tm1Mps>
  http://metadb.riken.jp/0011098I129S1Sv129X1SvJBlackSwissSwissWebsterGli1tm1AljGli1tm1AljPtch1tm1MpsPtch1tm1MpsGli1tm1AljPtch1tm1Mps
• abnormal spinal cord interneuron morphology_Gli2<tm1Alj>/Gli2<tm1Alj>,Ptch1<tm1Mps>/Ptch1<tm1Mps>
  http://metadb.riken.jp/0004100I129S1Sv129X1SvJSwissWebsterGli2tm1AljGli2tm1AljPtch1tm1MpsPtch1tm1MpsPtch1tm1MpsGli2tm1Alj
• small lung_Gli1<tm2Alj>/Gli1<tm2Alj>,Gli2<tm1Alj>/Gli2<tm1Alj>
  http://metadb.riken.jp/0003641I129SvBlackSwissSwissWebsterGli1tm2AljGli1tm2AljGli2tm1AljGli2tm1AljGli1tm2AljGli2tm1Alj
• abnormal spinal cord morphology_Gli2<tm1Alj>/Gli2<tm1Alj>,Ptch1<tm1Mps>/Ptch1<tm1Mps>
  http://metadb.riken.jp/0000955I129S1Sv129X1SvJSwissWebsterGli2tm1AljGli2tm1AljPtch1tm1MpsPtch1tm1MpsPtch1tm1MpsGli2tm1Alj
• persistence of notochord tissue_Gli1<tm2Alj>/Gli1<tm2Alj>,Gli2<tm1Alj>/Gli2<+>
  http://metadb.riken.jp/0004711I129SvBlackSwissSwissWebsterGli1tm2AljGli1tm2AljGli2tm1AljGli2Gli2tm1AljGli2Gli1tm2Alj
• exencephaly_Gli2<tm1Alj>/Gli2<tm1Alj>,Ptch1<tm1Mps>/Ptch1<tm1Mps>
  http://metadb.riken.jp/0000914I129S1Sv129X1SvJSwissWebsterGli2tm1AljGli2tm1AljPtch1tm1MpsPtch1tm1MpsPtch1tm1MpsGli2tm1Alj
• abnormal floor plate morphology_Gli1<tm2Alj>/Gli1<tm2Alj>,Gli2<tm1Alj>/Gli2<+>
  http://metadb.riken.jp/0000925I129SvBlackSwissSwissWebsterGli1tm2AljGli1tm2AljGli2tm1AljGli2Gli2tm1AljGli2Gli1tm2Alj
• embryonic lethality during organogenesis, complete penetrance_Ptch1<tm1Mps>/Ptch1<tm1Mps>
  http://metadb.riken.jp/0011098I129S1Sv129X1SvJSwissWebsterPtch1tm1MpsPtch1tm1MpsPtch1tm1Mps
• polydactyly_Gli1<tm2Alj>/Gli1<tm2Alj>,Gli2<tm1Alj>/Gli2<tm1Alj>
  http://metadb.riken.jp/0000562I129SvBlackSwissSwissWebsterGli1tm2AljGli1tm2AljGli2tm1AljGli2tm1AljGli1tm2AljGli2tm1Alj
• embryonic lethality during organogenesis, complete penetrance_Gli2<tm1Alj>/Gli2<tm1Alj>,Ptch1<tm1Mps>/Ptch1<tm1Mps>
  http://metadb.riken.jp/0011098I129S1Sv129X1SvJSwissWebsterGli2tm1AljGli2tm1AljPtch1tm1MpsPtch1tm1MpsPtch1tm1MpsGli2tm1Alj

class

http://purl.org/net/cito/citesAsAuthority

• Gli1<tm2Alj>
  http://metadb.riken.jp/db/mgi_rdf/MGI:2449767
• Tg(TK-cre)1Alj
  http://metadb.riken.jp/db/mgi_rdf/MGI:4437924

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• embryonic lethality during organogenesis, complete penetrance in RBRC06251
  http://metadb.riken.jp/db/rikenbrc_mouse/Phenotype_1017531