Paul S. Knoepfler, et.al., N-myc is essential during neurogenesis for the rapid expansion of progenitor cell populations and the inhibition of neuronal differentiation., Genes & development, 2002, 16

http://rdf.ncbi.nlm.nih.gov/pubmed/12381668

Paul S. Knoepfler, et.al., N-myc is essential during neurogenesis for the rapid expansion of progenitor cell populations and the inhibition of neuronal differentiation., Genes & development, 2002, 16

pubmed

allele

http://purl.org/net/cito/citesAsAuthority

• Mycn<tm1Psk>
  http://metadb.riken.jp/db/mgi_rdf/MGI:2388717
• Mycn<tm1.1Psk>
  http://metadb.riken.jp/db/mgi_rdf/MGI:2388718

class

http://purl.org/net/cito/citesAsAuthority

• Mycn<tm1Psk>
  http://metadb.riken.jp/db/mgi_rdf/MGI:2388717
• Mycn<tm1.1Psk>
  http://metadb.riken.jp/db/mgi_rdf/MGI:2388718

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• abnormal cerebellum morphology_Mycn<tm1Psk>/Mycn<tm1Psk>,Tg(Nes-cre)1Kln/0
  http://metadb.riken.jp/0000849I129C57BL6SJLMycntm1PskMycntm1PskTgNescre1Kln0Mycntm1PskTgNescre1Kln
• abnormal cerebral cortex morphology_Mycn<tm1Psk>/Mycn<tm1Psk>,Tg(Nes-cre)1Kln/0
  http://metadb.riken.jp/0000788I129C57BL6SJLMycntm1PskMycntm1PskTgNescre1Kln0Mycntm1PskTgNescre1Kln
• abnormal cerebellar Purkinje cell layer_Mycn<tm1Psk>/Mycn<tm1Psk>,Tg(Nes-cre)1Kln/0
  http://metadb.riken.jp/0000875I129C57BL6SJLMycntm1PskMycntm1PskTgNescre1Kln0Mycntm1PskTgNescre1Kln
• microphthalmia_Mycn<tm1Psk>/Mycn<tm1Psk>,Tg(Nes-cre)1Kln/0
  http://metadb.riken.jp/0001297I129C57BL6SJLMycntm1PskMycntm1PskTgNescre1Kln0Mycntm1PskTgNescre1Kln
• abnormal cerebellar molecular layer_Mycn<tm1Psk>/Mycn<tm1Psk>,Tg(Nes-cre)1Kln/0
  http://metadb.riken.jp/0000889I129C57BL6SJLMycntm1PskMycntm1PskTgNescre1Kln0Mycntm1PskTgNescre1Kln
• premature neuronal precursor differentiation_Mycn<tm1Psk>/Mycn<tm1Psk>,Tg(Nes-cre)1Kln/0
  http://metadb.riken.jp/0003424I129C57BL6SJLMycntm1PskMycntm1PskTgNescre1Kln0Mycntm1PskTgNescre1Kln
• prenatal lethality, complete penetrance_Mycn<tm1.1Psk>/Mycn<tm1.1Psk>
  http://metadb.riken.jp/0011091I129C57BL6Mycntm11PskMycntm11PskMycntm11Psk
• abnormal neuron differentiation_Mycn<tm1Psk>/Mycn<tm1Psk>,Tg(Nes-cre)1Kln/0
  http://metadb.riken.jp/0009937I129C57BL6SJLMycntm1PskMycntm1PskTgNescre1Kln0Mycntm1PskTgNescre1Kln
• abnormal cerebellum development_Mycn<tm1Psk>/Mycn<tm1Psk>,Tg(Nes-cre)1Kln/0
  http://metadb.riken.jp/0000854I129C57BL6SJLMycntm1PskMycntm1PskTgNescre1Kln0Mycntm1PskTgNescre1Kln
• small cerebellum_Mycn<tm1Psk>/Mycn<tm1Psk>,Tg(Nes-cre)1Kln/0
  http://metadb.riken.jp/0000852I129C57BL6SJLMycntm1PskMycntm1PskTgNescre1Kln0Mycntm1PskTgNescre1Kln
• abnormal cerebellar granule layer morphology_Mycn<tm1Psk>/Mycn<tm1Psk>,Tg(Nes-cre)1Kln/0
  http://metadb.riken.jp/0000886I129C57BL6SJLMycntm1PskMycntm1PskTgNescre1Kln0Mycntm1PskTgNescre1Kln
• ectopic Purkinje cell_Mycn<tm1Psk>/Mycn<tm1Psk>,Tg(Nes-cre)1Kln/0
  http://metadb.riken.jp/0000885I129C57BL6SJLMycntm1PskMycntm1PskTgNescre1Kln0Mycntm1PskTgNescre1Kln
• decreased neuronal precursor cell number_Mycn<tm1Psk>/Mycn<tm1Psk>,Tg(Nes-cre)1Kln/0
  http://metadb.riken.jp/0004981I129C57BL6SJLMycntm1PskMycntm1PskTgNescre1Kln0Mycntm1PskTgNescre1Kln
• decreased Purkinje cell number_Mycn<tm1Psk>/Mycn<tm1Psk>,Tg(Nes-cre)1Kln/0
  http://metadb.riken.jp/0000880I129C57BL6SJLMycntm1PskMycntm1PskTgNescre1Kln0Mycntm1PskTgNescre1Kln
• abnormal cerebellar foliation_Mycn<tm1Psk>/Mycn<tm1Psk>,Tg(Nes-cre)1Kln/0
  http://metadb.riken.jp/0000857I129C57BL6SJLMycntm1PskMycntm1PskTgNescre1Kln0Mycntm1PskTgNescre1Kln
• abnormal embryonic neuroepithelium morphology_Mycn<tm1Psk>/Mycn<tm1Psk>,Tg(Nes-cre)1Kln/0
  http://metadb.riken.jp/0004261I129C57BL6SJLMycntm1PskMycntm1PskTgNescre1Kln0Mycntm1PskTgNescre1Kln
• decreased embryonic neuroepithelium thickness_Mycn<tm1Psk>/Mycn<tm1Psk>,Tg(Nes-cre)1Kln/0
  http://metadb.riken.jp/0012703I129C57BL6SJLMycntm1PskMycntm1PskTgNescre1Kln0Mycntm1PskTgNescre1Kln
• abnormal cerebellum external granule cell layer morphology_Mycn<tm1Psk>/Mycn<tm1Psk>,Tg(Nes-cre)1Kln/0
  http://metadb.riken.jp/0000872I129C57BL6SJLMycntm1PskMycntm1PskTgNescre1Kln0Mycntm1PskTgNescre1Kln
• abnormal cortical ventricular zone morphology_Mycn<tm1Psk>/Mycn<tm1Psk>,Tg(Nes-cre)1Kln/0
  http://metadb.riken.jp/0008458I129C57BL6SJLMycntm1PskMycntm1PskTgNescre1Kln0Mycntm1PskTgNescre1Kln
• postnatal growth retardation_Mycn<tm1Psk>/Mycn<tm1Psk>,Tg(Nes-cre)1Kln/0
  http://metadb.riken.jp/0001732I129C57BL6SJLMycntm1PskMycntm1PskTgNescre1Kln0Mycntm1PskTgNescre1Kln
• abnormal neuronal precursor proliferation_Mycn<tm1Psk>/Mycn<tm1Psk>,Tg(Nes-cre)1Kln/0
  http://metadb.riken.jp/0004948I129C57BL6SJLMycntm1PskMycntm1PskTgNescre1Kln0Mycntm1PskTgNescre1Kln
• microcephaly_Mycn<tm1Psk>/Mycn<tm1Psk>,Tg(Nes-cre)1Kln/0
  http://metadb.riken.jp/0000433I129C57BL6SJLMycntm1PskMycntm1PskTgNescre1Kln0Mycntm1PskTgNescre1Kln
• decreased brain size_Mycn<tm1Psk>/Mycn<tm1Psk>,Tg(Nes-cre)1Kln/0
  http://metadb.riken.jp/0000774I129C57BL6SJLMycntm1PskMycntm1PskTgNescre1Kln0Mycntm1PskTgNescre1Kln