Mayumi. Naramura, et.al., c-Cbl and Cbl-b regulate T cell responsiveness by promoting ligand-induced TCR down-modulation., Nature immunology, 2002, 3

http://rdf.ncbi.nlm.nih.gov/pubmed/12415267

Mayumi. Naramura, et.al., c-Cbl and Cbl-b regulate T cell responsiveness by promoting ligand-induced TCR down-modulation., Nature immunology, 2002, 3

pubmed

allele

http://purl.org/net/cito/citesAsAuthority

• Cbl<tm2Hua>
  http://metadb.riken.jp/db/mgi_rdf/MGI:2446506

class

http://purl.org/net/cito/citesAsAuthority

• Cbl<tm2Hua>
  http://metadb.riken.jp/db/mgi_rdf/MGI:2446506

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• liver fibrosis_Cbl<tm2Hua>/Cbl<tm2Hua>,Cblb<tm1Hua>/Cblb<tm1Hua>,Tg(Lck-cre)I57Jxm/0
  http://metadb.riken.jp/0003333I129P2OlaHsdC57BL6ICRCbltm2HuaCbltm2HuaCblbtm1HuaCblbtm1HuaTgLckcreI57Jxm0TgLckcreI57JxmCblbtm1HuaCbltm2Hua
• enlarged spleen_Cbl<tm2Hua>/Cbl<tm2Hua>,Cblb<tm1Hua>/Cblb<tm1Hua>,Tg(Lck-cre)I57Jxm/0
  http://metadb.riken.jp/0000691I129P2OlaHsdC57BL6ICRCbltm2HuaCbltm2HuaCblbtm1HuaCblbtm1HuaTgLckcreI57Jxm0TgLckcreI57JxmCblbtm1HuaCbltm2Hua
• extramedullary hematopoiesis_Cbl<tm2Hua>/Cbl<tm2Hua>,Cblb<tm1Hua>/Cblb<tm1Hua>,Tg(Lck-cre)I57Jxm/0
  http://metadb.riken.jp/0000240I129P2OlaHsdC57BL6ICRCbltm2HuaCbltm2HuaCblbtm1HuaCblbtm1HuaTgLckcreI57Jxm0TgLckcreI57JxmCblbtm1HuaCbltm2Hua
• premature death_Cbl<tm2Hua>/Cbl<tm2Hua>,Cblb<tm1Hua>/Cblb<tm1Hua>,Tg(Lck-cre)I57Jxm/0
  http://metadb.riken.jp/0002083I129P2OlaHsdC57BL6ICRCbltm2HuaCbltm2HuaCblbtm1HuaCblbtm1HuaTgLckcreI57Jxm0TgLckcreI57JxmCblbtm1HuaCbltm2Hua
• abnormal T cell morphology_Cbl<tm2Hua>/Cbl<tm2Hua>,Cblb<tm1Hua>/Cblb<tm1Hua>,Tg(Lck-cre)I57Jxm/0
  http://metadb.riken.jp/0008037I129P2OlaHsdC57BL6ICRCbltm2HuaCbltm2HuaCblbtm1HuaCblbtm1HuaTgLckcreI57Jxm0TgLckcreI57JxmCblbtm1HuaCbltm2Hua
• decreased body weight_Cbl<tm2Hua>/Cbl<tm2Hua>,Cblb<tm1Hua>/Cblb<tm1Hua>,Tg(Lck-cre)I57Jxm/0
  http://metadb.riken.jp/0001262I129P2OlaHsdC57BL6ICRCbltm2HuaCbltm2HuaCblbtm1HuaCblbtm1HuaTgLckcreI57Jxm0TgLckcreI57JxmCblbtm1HuaCbltm2Hua
• increased T cell proliferation_Cbl<tm2Hua>/Cbl<tm2Hua>,Cblb<tm1Hua>/Cblb<tm1Hua>,Tg(Lck-cre)I57Jxm/0
  http://metadb.riken.jp/0005348I129P2OlaHsdC57BL6ICRCbltm2HuaCbltm2HuaCblbtm1HuaCblbtm1HuaTgLckcreI57Jxm0TgLckcreI57JxmCblbtm1HuaCbltm2Hua
• dermatitis_Cbl<tm2Hua>/Cbl<tm2Hua>,Cblb<tm1Hua>/Cblb<tm1Hua>,Tg(Lck-cre)I57Jxm/0
  http://metadb.riken.jp/0001194I129P2OlaHsdC57BL6ICRCbltm2HuaCbltm2HuaCblbtm1HuaCblbtm1HuaTgLckcreI57Jxm0TgLckcreI57JxmCblbtm1HuaCbltm2Hua
• abnormal immune system physiology_Cbl<tm2Hua>/Cbl<tm2Hua>,Cblb<tm1Hua>/Cblb<tm1Hua>,Tg(Lck-cre)I57Jxm/0
  http://metadb.riken.jp/0001790I129P2OlaHsdC57BL6ICRCbltm2HuaCbltm2HuaCblbtm1HuaCblbtm1HuaTgLckcreI57Jxm0TgLckcreI57JxmCblbtm1HuaCbltm2Hua
• abnormal blood vessel morphology_Cbl<tm2Hua>/Cbl<tm2Hua>,Cblb<tm1Hua>/Cblb<tm1Hua>,Tg(Lck-cre)I57Jxm/0
  http://metadb.riken.jp/0001614I129P2OlaHsdC57BL6ICRCbltm2HuaCbltm2HuaCblbtm1HuaCblbtm1HuaTgLckcreI57Jxm0TgLckcreI57JxmCblbtm1HuaCbltm2Hua