Jay L. Vivian, et.al., An allelic series of mutations in Smad2 and Smad4 identified in a genotype-based screen of N-ethyl-N- nitrosourea-mutagenized mouse embryonic stem cells., Proceedings of the National Academy of Sciences of the United States of America, 2002, 99

http://rdf.ncbi.nlm.nih.gov/pubmed/12432092

Jay L. Vivian, et.al., An allelic series of mutations in Smad2 and Smad4 identified in a genotype-based screen of N-ethyl-N- nitrosourea-mutagenized mouse embryonic stem cells., Proceedings of the National Academy of Sciences of the United States of America, 2002, 99

pubmed

allele

http://purl.org/net/cito/citesAsAuthority

• Smad2<m1Mag>
  http://metadb.riken.jp/db/mgi_rdf/MGI:2447199
• Smad4<m1Mag>
  http://metadb.riken.jp/db/mgi_rdf/MGI:2447202
• Smad4<m2Mag>
  http://metadb.riken.jp/db/mgi_rdf/MGI:2447204
• Smad4<m3Mag>
  http://metadb.riken.jp/db/mgi_rdf/MGI:2447207
• Smad4<m4Mag>
  http://metadb.riken.jp/db/mgi_rdf/MGI:2447208

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• abnormal heart development_Smad2<m1Mag>/Smad2<m1Mag>
  http://metadb.riken.jp/0000267EI129SSvBlackSwissorI129SSvC57BL6Smad2m1MagSmad2m1MagSmad2m1Mag
• abnormal heart tube morphology_Smad2<m1Mag>/Smad2<m1Mag>
  http://metadb.riken.jp/0000270EI129SSvBlackSwissorI129SSvC57BL6Smad2m1MagSmad2m1MagSmad2m1Mag
• absent notochord_Smad2<m1Mag>/Smad2<m1Mag>
  http://metadb.riken.jp/0000932EI129SSvBlackSwissorI129SSvC57BL6Smad2m1MagSmad2m1MagSmad2m1Mag
• absent mesoderm_Smad4<m4Mag>/Smad4<tm1Cxd>
  http://metadb.riken.jp/0001683EI129SSv129S6SvEvTacBlackSwissorI129SSv129S6SvEvTacC57BL6Smad4m4MagSmad4tm1CxdSmad4tm1CxdSmad4m4Mag
• absent mesoderm_Smad4<m4Mag>/Smad4<m4Mag>
  http://metadb.riken.jp/0001683EI129SSvBlackSwissorI129SSvC57BL6Smad4m4MagSmad4m4MagSmad4m4Mag
• failure to gastrulate_Smad4<m4Mag>/Smad4<tm1Cxd>
  http://metadb.riken.jp/0001696EI129SSv129S6SvEvTacBlackSwissorI129SSv129S6SvEvTacC57BL6Smad4m4MagSmad4tm1CxdSmad4tm1CxdSmad4m4Mag
他21件を見る
• failure to gastrulate_Smad4<m4Mag>/Smad4<m4Mag>
  http://metadb.riken.jp/0001696EI129SSvBlackSwissorI129SSvC57BL6Smad4m4MagSmad4m4MagSmad4m4Mag
• abnormal embryonic tissue morphology_Smad2<m1Mag>/Smad2<tm1Rob>
  http://metadb.riken.jp/0002085EI129SSv129SSvEvBlackSwissorI129SSv129SSvEvC57BL6Smad2m1MagSmad2tm1RobSmad2tm1RobSmad2m1Mag
• abnormal embryonic tissue morphology_Smad2<m1Mag>/Smad2<m1Mag>
  http://metadb.riken.jp/0002085EI129SSvBlackSwissorI129SSvC57BL6Smad2m1MagSmad2m1MagSmad2m1Mag
• no abnormal phenotype detected_Smad4<m1Mag>/Smad4<tm1Cxd>
  http://metadb.riken.jp/0002169EI129SSv129S6SvEvTacBlackSwissorI129SSv129S6SvEvTacC57BL6Smad4m1MagSmad4tm1CxdSmad4tm1CxdSmad4m1Mag
• no abnormal phenotype detected_Smad4<m2Mag>/Smad4<tm1Cxd>
  http://metadb.riken.jp/0002169EI129SSv129S6SvEvTacBlackSwissorI129SSv129S6SvEvTacC57BL6Smad4m2MagSmad4tm1CxdSmad4m2MagSmad4tm1Cxd
• no abnormal phenotype detected_Smad4<m3Mag>/Smad4<tm1Cxd>
  http://metadb.riken.jp/0002169EI129SSv129S6SvEvTacBlackSwissorI129SSv129S6SvEvTacC57BL6Smad4m3MagSmad4tm1CxdSmad4tm1CxdSmad4m3Mag
• no abnormal phenotype detected_Smad2<m1Mag>/Smad2<+>
  http://metadb.riken.jp/0002169EI129SSvBlackSwissorI129SSvC57BL6Smad2m1MagSmad2Smad2Smad2m1Mag
• no abnormal phenotype detected_Smad4<m1Mag>/Smad4<m1Mag>
  http://metadb.riken.jp/0002169EI129SSvBlackSwissorI129SSvC57BL6Smad4m1MagSmad4m1MagSmad4m1Mag
• no abnormal phenotype detected_Smad4<m2Mag>/Smad4<m2Mag>
  http://metadb.riken.jp/0002169EI129SSvBlackSwissorI129SSvC57BL6Smad4m2MagSmad4m2MagSmad4m2Mag
• no abnormal phenotype detected_Smad4<m3Mag>/Smad4<m3Mag>
  http://metadb.riken.jp/0002169EI129SSvBlackSwissorI129SSvC57BL6Smad4m3MagSmad4m3MagSmad4m3Mag
• embryonic growth retardation_Smad4<m4Mag>/Smad4<tm1Cxd>
  http://metadb.riken.jp/0003984EI129SSv129S6SvEvTacBlackSwissorI129SSv129S6SvEvTacC57BL6Smad4m4MagSmad4tm1CxdSmad4tm1CxdSmad4m4Mag
• embryonic growth retardation_Smad4<m4Mag>/Smad4<m4Mag>
  http://metadb.riken.jp/0003984EI129SSvBlackSwissorI129SSvC57BL6Smad4m4MagSmad4m4MagSmad4m4Mag
• abnormal dorsal aorta morphology_Smad2<m1Mag>/Smad2<m1Mag>
  http://metadb.riken.jp/0004787EI129SSvBlackSwissorI129SSvC57BL6Smad2m1MagSmad2m1MagSmad2m1Mag
• failure of chorioallantoic fusion_Smad2<m1Mag>/Smad2<m1Mag>
  http://metadb.riken.jp/0009657EI129SSvBlackSwissorI129SSvC57BL6Smad2m1MagSmad2m1MagSmad2m1Mag
• embryonic lethality, complete penetrance_Smad2<m1Mag>/Smad2<m1Mag>
  http://metadb.riken.jp/0011092EI129SSvBlackSwissorI129SSvC57BL6Smad2m1MagSmad2m1MagSmad2m1Mag
• embryonic lethality between implantation and somite formation, complete penetrance_Smad4<m4Mag>/Smad4<tm1Cxd>
  http://metadb.riken.jp/0011096EI129SSv129S6SvEvTacBlackSwissorI129SSv129S6SvEvTacC57BL6Smad4m4MagSmad4tm1CxdSmad4tm1CxdSmad4m4Mag
• embryonic lethality between implantation and somite formation, complete penetrance_Smad4<m4Mag>/Smad4<m4Mag>
  http://metadb.riken.jp/0011096EI129SSvBlackSwissorI129SSvC57BL6Smad4m4MagSmad4m4MagSmad4m4Mag
• embryonic lethality during organogenesis, complete penetrance_Smad2<m1Mag>/Smad2<tm1Rob>
  http://metadb.riken.jp/0011098EI129SSv129SSvEvBlackSwissorI129SSv129SSvEvC57BL6Smad2m1MagSmad2tm1RobSmad2tm1RobSmad2m1Mag
• absent foregut_Smad2<m1Mag>/Smad2<m1Mag>
  http://metadb.riken.jp/0012083EI129SSvBlackSwissorI129SSvC57BL6Smad2m1MagSmad2m1MagSmad2m1Mag
• rostral body truncation_Smad2<m1Mag>/Smad2<m1Mag>
  http://metadb.riken.jp/0012157EI129SSvBlackSwissorI129SSvC57BL6Smad2m1MagSmad2m1MagSmad2m1Mag
• absent optic placodes_Smad2<m1Mag>/Smad2<m1Mag>
  http://metadb.riken.jp/0012170EI129SSvBlackSwissorI129SSvC57BL6Smad2m1MagSmad2m1MagSmad2m1Mag

class

http://purl.org/net/cito/citesAsAuthority

• Smad2<m1Mag>
  http://metadb.riken.jp/db/mgi_rdf/MGI:2447199
• Smad4<m1Mag>
  http://metadb.riken.jp/db/mgi_rdf/MGI:2447202
• Smad4<m2Mag>
  http://metadb.riken.jp/db/mgi_rdf/MGI:2447204
• Smad4<m3Mag>
  http://metadb.riken.jp/db/mgi_rdf/MGI:2447207
• Smad4<m4Mag>
  http://metadb.riken.jp/db/mgi_rdf/MGI:2447208