Janelle. Miller, et.al., The core-binding factor beta subunit is required for bone formation and hematopoietic maturation., Nature genetics, 2002, 32

http://rdf.ncbi.nlm.nih.gov/pubmed/12434155

Janelle. Miller, et.al., The core-binding factor beta subunit is required for bone formation and hematopoietic maturation., Nature genetics, 2002, 32

pubmed

allele

http://purl.org/net/cito/citesAsAuthority

• Tg(Tek-GFP/Cbfb)2Spe
  http://metadb.riken.jp/db/mgi_rdf/MGI:2447351
• Tg(Tek-GFP/Cbfb)1Spe
  http://metadb.riken.jp/db/mgi_rdf/MGI:2447350

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• eyelids open at birth_Cbfb<tm1Spe>/Cbfb<tm1Spe>,Tg(Tek-GFP/Cbfb)2Spe/0
  http://metadb.riken.jp/0001302EI129S4SvJaeBALBcCD1SwissWebsterorI129S4SvJaeC57BL6CD1SwissWebsterCbfbtm1SpeCbfbtm1SpeTgTekGFPCbfb2Spe0TgTekGFPCbfb2SpeCbfbtm1Spe
• abnormal chondrocyte morphology_Cbfb<tm1Spe>/Cbfb<tm1Spe>,Tg(Tek-GFP/Cbfb)2Spe/0
  http://metadb.riken.jp/0000166EI129S4SvJaeBALBcCD1SwissWebsterorI129S4SvJaeC57BL6CD1SwissWebsterCbfbtm1SpeCbfbtm1SpeTgTekGFPCbfb2Spe0TgTekGFPCbfb2SpeCbfbtm1Spe
• abnormal definitive hematopoiesis_Cbfb<tm1Spe>/Cbfb<tm1Spe>,Tg(Tek-GFP/Cbfb)1Spe/0
  http://metadb.riken.jp/0002123EI129S4SvJaeBALBcCD1orI129S4SvJaeC57BL6CD1Cbfbtm1SpeCbfbtm1SpeTgTekGFPCbfb1Spe0Cbfbtm1SpeTgTekGFPCbfb1Spe
• increased erythroid progenitor cell number_Cbfb<tm1Spe>/Cbfb<tm1Spe>,Tg(Tek-GFP/Cbfb)1Spe/0
  http://metadb.riken.jp/0003135EI129S4SvJaeBALBcCD1orI129S4SvJaeC57BL6CD1Cbfbtm1SpeCbfbtm1SpeTgTekGFPCbfb1Spe0Cbfbtm1SpeTgTekGFPCbfb1Spe
• short snout_Cbfb<tm1Spe>/Cbfb<tm1Spe>,Tg(Tek-GFP/Cbfb)2Spe/0
  http://metadb.riken.jp/0000445EI129S4SvJaeBALBcCD1SwissWebsterorI129S4SvJaeC57BL6CD1SwissWebsterCbfbtm1SpeCbfbtm1SpeTgTekGFPCbfb2Spe0TgTekGFPCbfb2SpeCbfbtm1Spe
• protruding tongue_Cbfb<tm1Spe>/Cbfb<tm1Spe>,Tg(Tek-GFP/Cbfb)2Spe/0
  http://metadb.riken.jp/0009908EI129S4SvJaeBALBcCD1SwissWebsterorI129S4SvJaeC57BL6CD1SwissWebsterCbfbtm1SpeCbfbtm1SpeTgTekGFPCbfb2Spe0TgTekGFPCbfb2SpeCbfbtm1Spe
• bowed tibia_Cbfb<tm1Spe>/Cbfb<tm1Spe>,Tg(Tek-GFP/Cbfb)2Spe/0
  http://metadb.riken.jp/0004358EI129S4SvJaeBALBcCD1SwissWebsterorI129S4SvJaeC57BL6CD1SwissWebsterCbfbtm1SpeCbfbtm1SpeTgTekGFPCbfb2Spe0TgTekGFPCbfb2SpeCbfbtm1Spe
• short limbs_Cbfb<tm1Spe>/Cbfb<tm1Spe>,Tg(Tek-GFP/Cbfb)1Spe/0
  http://metadb.riken.jp/0000547EI129S4SvJaeBALBcCD1orI129S4SvJaeC57BL6CD1Cbfbtm1SpeCbfbtm1SpeTgTekGFPCbfb1Spe0Cbfbtm1SpeTgTekGFPCbfb1Spe
• increased CD4-positive, alpha beta T cell number_Cbfb<tm1Spe>/Cbfb<tm1Spe>,Tg(Tek-GFP/Cbfb)2Spe/0
  http://metadb.riken.jp/0008074EI129S4SvJaeBALBcCD1SwissWebsterorI129S4SvJaeC57BL6CD1SwissWebsterCbfbtm1SpeCbfbtm1SpeTgTekGFPCbfb2Spe0TgTekGFPCbfb2SpeCbfbtm1Spe
• abnormal long bone hypertrophic chondrocyte zone_Cbfb<tm1Spe>/Cbfb<tm1Spe>,Tg(Tek-GFP/Cbfb)1Spe/0
  http://metadb.riken.jp/0000165EI129S4SvJaeBALBcCD1orI129S4SvJaeC57BL6CD1Cbfbtm1SpeCbfbtm1SpeTgTekGFPCbfb1Spe0Cbfbtm1SpeTgTekGFPCbfb1Spe
• spleen hypoplasia_Cbfb<tm1Spe>/Cbfb<tm1Spe>,Tg(Tek-GFP/Cbfb)2Spe/0
  http://metadb.riken.jp/0000694EI129S4SvJaeBALBcCD1SwissWebsterorI129S4SvJaeC57BL6CD1SwissWebsterCbfbtm1SpeCbfbtm1SpeTgTekGFPCbfb2Spe0TgTekGFPCbfb2SpeCbfbtm1Spe
• delayed endochondral bone ossification_Cbfb<tm1Spe>/Cbfb<tm1Spe>,Tg(Tek-GFP/Cbfb)2Spe/0
  http://metadb.riken.jp/0003419EI129S4SvJaeBALBcCD1SwissWebsterorI129S4SvJaeC57BL6CD1SwissWebsterCbfbtm1SpeCbfbtm1SpeTgTekGFPCbfb2Spe0TgTekGFPCbfb2SpeCbfbtm1Spe
• protruding tongue_Cbfb<tm1Spe>/Cbfb<tm1Spe>,Tg(Tek-GFP/Cbfb)1Spe/0
  http://metadb.riken.jp/0009908EI129S4SvJaeBALBcCD1orI129S4SvJaeC57BL6CD1Cbfbtm1SpeCbfbtm1SpeTgTekGFPCbfb1Spe0Cbfbtm1SpeTgTekGFPCbfb1Spe
• spleen hypoplasia_Cbfb<tm1Spe>/Cbfb<tm1Spe>,Tg(Tek-GFP/Cbfb)1Spe/0
  http://metadb.riken.jp/0000694EI129S4SvJaeBALBcCD1orI129S4SvJaeC57BL6CD1Cbfbtm1SpeCbfbtm1SpeTgTekGFPCbfb1Spe0Cbfbtm1SpeTgTekGFPCbfb1Spe
• bowed tibia_Cbfb<tm1Spe>/Cbfb<tm1Spe>,Tg(Tek-GFP/Cbfb)1Spe/0
  http://metadb.riken.jp/0004358EI129S4SvJaeBALBcCD1orI129S4SvJaeC57BL6CD1Cbfbtm1SpeCbfbtm1SpeTgTekGFPCbfb1Spe0Cbfbtm1SpeTgTekGFPCbfb1Spe
• abnormal myelopoiesis_Cbfb<tm1Spe>/Cbfb<tm1Spe>,Tg(Tek-GFP/Cbfb)1Spe/0
  http://metadb.riken.jp/0001601EI129S4SvJaeBALBcCD1orI129S4SvJaeC57BL6CD1Cbfbtm1SpeCbfbtm1SpeTgTekGFPCbfb1Spe0Cbfbtm1SpeTgTekGFPCbfb1Spe
• abnormal splenic cell ratio_Cbfb<tm1Spe>/Cbfb<tm1Spe>,Tg(Tek-GFP/Cbfb)2Spe/0
  http://metadb.riken.jp/0008826EI129S4SvJaeBALBcCD1SwissWebsterorI129S4SvJaeC57BL6CD1SwissWebsterCbfbtm1SpeCbfbtm1SpeTgTekGFPCbfb2Spe0TgTekGFPCbfb2SpeCbfbtm1Spe
• increased CD4-positive, alpha beta T cell number_Cbfb<tm1Spe>/Cbfb<tm1Spe>,Tg(Tek-GFP/Cbfb)1Spe/0
  http://metadb.riken.jp/0008074EI129S4SvJaeBALBcCD1orI129S4SvJaeC57BL6CD1Cbfbtm1SpeCbfbtm1SpeTgTekGFPCbfb1Spe0Cbfbtm1SpeTgTekGFPCbfb1Spe
• small thymus_Cbfb<tm1Spe>/Cbfb<tm1Spe>,Tg(Tek-GFP/Cbfb)1Spe/0
  http://metadb.riken.jp/0000706EI129S4SvJaeBALBcCD1orI129S4SvJaeC57BL6CD1Cbfbtm1SpeCbfbtm1SpeTgTekGFPCbfb1Spe0Cbfbtm1SpeTgTekGFPCbfb1Spe
• abnormal osteoblast morphology_Cbfb<tm1Spe>/Cbfb<tm1Spe>,Tg(Tek-GFP/Cbfb)1Spe/0
  http://metadb.riken.jp/0004986EI129S4SvJaeBALBcCD1orI129S4SvJaeC57BL6CD1Cbfbtm1SpeCbfbtm1SpeTgTekGFPCbfb1Spe0Cbfbtm1SpeTgTekGFPCbfb1Spe
• abnormal osteoblast morphology_Cbfb<tm1Spe>/Cbfb<tm1Spe>,Tg(Tek-GFP/Cbfb)2Spe/0
  http://metadb.riken.jp/0004986EI129S4SvJaeBALBcCD1SwissWebsterorI129S4SvJaeC57BL6CD1SwissWebsterCbfbtm1SpeCbfbtm1SpeTgTekGFPCbfb2Spe0TgTekGFPCbfb2SpeCbfbtm1Spe
• abnormal definitive hematopoiesis_Cbfb<tm1Spe>/Cbfb<tm1Spe>,Tg(Tek-GFP/Cbfb)2Spe/0
  http://metadb.riken.jp/0002123EI129S4SvJaeBALBcCD1SwissWebsterorI129S4SvJaeC57BL6CD1SwissWebsterCbfbtm1SpeCbfbtm1SpeTgTekGFPCbfb2Spe0TgTekGFPCbfb2SpeCbfbtm1Spe
• delayed bone ossification_Cbfb<tm1Spe>/Cbfb<tm1Spe>,Tg(Tek-GFP/Cbfb)1Spe/0
  http://metadb.riken.jp/0000060EI129S4SvJaeBALBcCD1orI129S4SvJaeC57BL6CD1Cbfbtm1SpeCbfbtm1SpeTgTekGFPCbfb1Spe0Cbfbtm1SpeTgTekGFPCbfb1Spe
• abnormal myelopoiesis_Cbfb<tm1Spe>/Cbfb<tm1Spe>,Tg(Tek-GFP/Cbfb)2Spe/0
  http://metadb.riken.jp/0001601EI129S4SvJaeBALBcCD1SwissWebsterorI129S4SvJaeC57BL6CD1SwissWebsterCbfbtm1SpeCbfbtm1SpeTgTekGFPCbfb2Spe0TgTekGFPCbfb2SpeCbfbtm1Spe
• short snout_Cbfb<tm1Spe>/Cbfb<tm1Spe>,Tg(Tek-GFP/Cbfb)1Spe/0
  http://metadb.riken.jp/0000445EI129S4SvJaeBALBcCD1orI129S4SvJaeC57BL6CD1Cbfbtm1SpeCbfbtm1SpeTgTekGFPCbfb1Spe0Cbfbtm1SpeTgTekGFPCbfb1Spe
• abnormal common myeloid progenitor cell morphology_Cbfb<tm1Spe>/Cbfb<tm1Spe>,Tg(Tek-GFP/Cbfb)2Spe/0
  http://metadb.riken.jp/0006410EI129S4SvJaeBALBcCD1SwissWebsterorI129S4SvJaeC57BL6CD1SwissWebsterCbfbtm1SpeCbfbtm1SpeTgTekGFPCbfb2Spe0TgTekGFPCbfb2SpeCbfbtm1Spe
• increased hematopoietic stem cell number_Cbfb<tm1Spe>/Cbfb<tm1Spe>,Tg(Tek-GFP/Cbfb)1Spe/0
  http://metadb.riken.jp/0004809EI129S4SvJaeBALBcCD1orI129S4SvJaeC57BL6CD1Cbfbtm1SpeCbfbtm1SpeTgTekGFPCbfb1Spe0Cbfbtm1SpeTgTekGFPCbfb1Spe
• abnormal liver morphology_Cbfb<tm1Spe>/Cbfb<tm1Spe>,Tg(Tek-GFP/Cbfb)2Spe/0
  http://metadb.riken.jp/0000598EI129S4SvJaeBALBcCD1SwissWebsterorI129S4SvJaeC57BL6CD1SwissWebsterCbfbtm1SpeCbfbtm1SpeTgTekGFPCbfb2Spe0TgTekGFPCbfb2SpeCbfbtm1Spe
• small thymus_Cbfb<tm1Spe>/Cbfb<tm1Spe>,Tg(Tek-GFP/Cbfb)2Spe/0
  http://metadb.riken.jp/0000706EI129S4SvJaeBALBcCD1SwissWebsterorI129S4SvJaeC57BL6CD1SwissWebsterCbfbtm1SpeCbfbtm1SpeTgTekGFPCbfb2Spe0TgTekGFPCbfb2SpeCbfbtm1Spe
• eyelids open at birth_Cbfb<tm1Spe>/Cbfb<tm1Spe>,Tg(Tek-GFP/Cbfb)1Spe/0
  http://metadb.riken.jp/0001302EI129S4SvJaeBALBcCD1orI129S4SvJaeC57BL6CD1Cbfbtm1SpeCbfbtm1SpeTgTekGFPCbfb1Spe0Cbfbtm1SpeTgTekGFPCbfb1Spe
• delayed endochondral bone ossification_Cbfb<tm1Spe>/Cbfb<tm1Spe>,Tg(Tek-GFP/Cbfb)1Spe/0
  http://metadb.riken.jp/0003419EI129S4SvJaeBALBcCD1orI129S4SvJaeC57BL6CD1Cbfbtm1SpeCbfbtm1SpeTgTekGFPCbfb1Spe0Cbfbtm1SpeTgTekGFPCbfb1Spe
• delayed bone ossification_Cbfb<tm1Spe>/Cbfb<tm1Spe>,Tg(Tek-GFP/Cbfb)2Spe/0
  http://metadb.riken.jp/0000060EI129S4SvJaeBALBcCD1SwissWebsterorI129S4SvJaeC57BL6CD1SwissWebsterCbfbtm1SpeCbfbtm1SpeTgTekGFPCbfb2Spe0TgTekGFPCbfb2SpeCbfbtm1Spe
• delayed intramembranous bone ossification_Cbfb<tm1Spe>/Cbfb<tm1Spe>,Tg(Tek-GFP/Cbfb)2Spe/0
  http://metadb.riken.jp/0003420EI129S4SvJaeBALBcCD1SwissWebsterorI129S4SvJaeC57BL6CD1SwissWebsterCbfbtm1SpeCbfbtm1SpeTgTekGFPCbfb2Spe0TgTekGFPCbfb2SpeCbfbtm1Spe
• abnormal long bone hypertrophic chondrocyte zone_Cbfb<tm1Spe>/Cbfb<tm1Spe>,Tg(Tek-GFP/Cbfb)2Spe/0
  http://metadb.riken.jp/0000165EI129S4SvJaeBALBcCD1SwissWebsterorI129S4SvJaeC57BL6CD1SwissWebsterCbfbtm1SpeCbfbtm1SpeTgTekGFPCbfb2Spe0TgTekGFPCbfb2SpeCbfbtm1Spe
• abnormal chondrocyte morphology_Cbfb<tm1Spe>/Cbfb<tm1Spe>,Tg(Tek-GFP/Cbfb)1Spe/0
  http://metadb.riken.jp/0000166EI129S4SvJaeBALBcCD1orI129S4SvJaeC57BL6CD1Cbfbtm1SpeCbfbtm1SpeTgTekGFPCbfb1Spe0Cbfbtm1SpeTgTekGFPCbfb1Spe
• delayed intramembranous bone ossification_Cbfb<tm1Spe>/Cbfb<tm1Spe>,Tg(Tek-GFP/Cbfb)1Spe/0
  http://metadb.riken.jp/0003420EI129S4SvJaeBALBcCD1orI129S4SvJaeC57BL6CD1Cbfbtm1SpeCbfbtm1SpeTgTekGFPCbfb1Spe0Cbfbtm1SpeTgTekGFPCbfb1Spe
• short limbs_Cbfb<tm1Spe>/Cbfb<tm1Spe>,Tg(Tek-GFP/Cbfb)2Spe/0
  http://metadb.riken.jp/0000547EI129S4SvJaeBALBcCD1SwissWebsterorI129S4SvJaeC57BL6CD1SwissWebsterCbfbtm1SpeCbfbtm1SpeTgTekGFPCbfb2Spe0TgTekGFPCbfb2SpeCbfbtm1Spe
• increased erythroid progenitor cell number_Cbfb<tm1Spe>/Cbfb<tm1Spe>,Tg(Tek-GFP/Cbfb)2Spe/0
  http://metadb.riken.jp/0003135EI129S4SvJaeBALBcCD1SwissWebsterorI129S4SvJaeC57BL6CD1SwissWebsterCbfbtm1SpeCbfbtm1SpeTgTekGFPCbfb2Spe0TgTekGFPCbfb2SpeCbfbtm1Spe
• perinatal lethality, complete penetrance_Cbfb<tm1Spe>/Cbfb<tm1Spe>,Tg(Tek-GFP/Cbfb)2Spe/0
  http://metadb.riken.jp/0011089EI129S4SvJaeBALBcCD1SwissWebsterorI129S4SvJaeC57BL6CD1SwissWebsterCbfbtm1SpeCbfbtm1SpeTgTekGFPCbfb2Spe0TgTekGFPCbfb2SpeCbfbtm1Spe
• increased hematopoietic stem cell number_Cbfb<tm1Spe>/Cbfb<tm1Spe>,Tg(Tek-GFP/Cbfb)2Spe/0
  http://metadb.riken.jp/0004809EI129S4SvJaeBALBcCD1SwissWebsterorI129S4SvJaeC57BL6CD1SwissWebsterCbfbtm1SpeCbfbtm1SpeTgTekGFPCbfb2Spe0TgTekGFPCbfb2SpeCbfbtm1Spe
• abnormal splenic cell ratio_Cbfb<tm1Spe>/Cbfb<tm1Spe>,Tg(Tek-GFP/Cbfb)1Spe/0
  http://metadb.riken.jp/0008826EI129S4SvJaeBALBcCD1orI129S4SvJaeC57BL6CD1Cbfbtm1SpeCbfbtm1SpeTgTekGFPCbfb1Spe0Cbfbtm1SpeTgTekGFPCbfb1Spe
• abnormal erythropoiesis_Cbfb<tm1Spe>/Cbfb<tm1Spe>,Tg(Tek-GFP/Cbfb)1Spe/0
  http://metadb.riken.jp/0000245EI129S4SvJaeBALBcCD1orI129S4SvJaeC57BL6CD1Cbfbtm1SpeCbfbtm1SpeTgTekGFPCbfb1Spe0Cbfbtm1SpeTgTekGFPCbfb1Spe
• abnormal liver morphology_Cbfb<tm1Spe>/Cbfb<tm1Spe>,Tg(Tek-GFP/Cbfb)1Spe/0
  http://metadb.riken.jp/0000598EI129S4SvJaeBALBcCD1orI129S4SvJaeC57BL6CD1Cbfbtm1SpeCbfbtm1SpeTgTekGFPCbfb1Spe0Cbfbtm1SpeTgTekGFPCbfb1Spe
• perinatal lethality, complete penetrance_Cbfb<tm1Spe>/Cbfb<tm1Spe>,Tg(Tek-GFP/Cbfb)1Spe/0
  http://metadb.riken.jp/0011089EI129S4SvJaeBALBcCD1orI129S4SvJaeC57BL6CD1Cbfbtm1SpeCbfbtm1SpeTgTekGFPCbfb1Spe0Cbfbtm1SpeTgTekGFPCbfb1Spe
• abnormal erythropoiesis_Cbfb<tm1Spe>/Cbfb<tm1Spe>,Tg(Tek-GFP/Cbfb)2Spe/0
  http://metadb.riken.jp/0000245EI129S4SvJaeBALBcCD1SwissWebsterorI129S4SvJaeC57BL6CD1SwissWebsterCbfbtm1SpeCbfbtm1SpeTgTekGFPCbfb2Spe0TgTekGFPCbfb2SpeCbfbtm1Spe
• abnormal common myeloid progenitor cell morphology_Cbfb<tm1Spe>/Cbfb<tm1Spe>,Tg(Tek-GFP/Cbfb)1Spe/0
  http://metadb.riken.jp/0006410EI129S4SvJaeBALBcCD1orI129S4SvJaeC57BL6CD1Cbfbtm1SpeCbfbtm1SpeTgTekGFPCbfb1Spe0Cbfbtm1SpeTgTekGFPCbfb1Spe

class

http://purl.org/net/cito/citesAsAuthority

• Tg(Tek-GFP/Cbfb)2Spe
  http://metadb.riken.jp/db/mgi_rdf/MGI:2447351
• Tg(Tek-GFP/Cbfb)1Spe
  http://metadb.riken.jp/db/mgi_rdf/MGI:2447350