David L. Mack, et.al., Down-regulation of the myeloid homeobox protein Hex is essential for normal T-cell development., Immunology, 2002, 107

http://rdf.ncbi.nlm.nih.gov/pubmed/12460189

David L. Mack, et.al., Down-regulation of the myeloid homeobox protein Hex is essential for normal T-cell development., Immunology, 2002, 107

pubmed

allele

http://purl.org/net/cito/citesAsAuthority

• Tg(ITGAL-Hhex)2Hro
  http://metadb.riken.jp/db/mgi_rdf/MGI:2448672
• Tg(Lck-Hhex)1Hro
  http://metadb.riken.jp/db/mgi_rdf/MGI:2448671

class

http://purl.org/net/cito/citesAsAuthority

• Tg(ITGAL-Hhex)2Hro
  http://metadb.riken.jp/db/mgi_rdf/MGI:2448672
• Tg(Lck-Hhex)1Hro
  http://metadb.riken.jp/db/mgi_rdf/MGI:2448671

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• abnormal double-negative T cell morphology_Tg(Lck-Hhex)1Hro/0
  http://metadb.riken.jp/0002407C3HeBFeJTgLckHhex1HroTgLckHhex1Hro0TgLckHhex1Hro
• abnormal definitive hematopoiesis_Tg(ITGAL-Hhex)2Hro/0
  http://metadb.riken.jp/0002123C3HeBFeJTgITGALHhex2HroTgITGALHhex2Hro0TgITGALHhex2Hro
• decreased T cell number_Tg(Lck-Hhex)1Hro/0
  http://metadb.riken.jp/0005018C3HeBFeJTgLckHhex1HroTgLckHhex1Hro0TgLckHhex1Hro
• increased CD8-positive, alpha-beta T cell number_Tg(ITGAL-Hhex)2Hro/0
  http://metadb.riken.jp/0008078C3HeBFeJTgITGALHhex2HroTgITGALHhex2Hro0TgITGALHhex2Hro
• abnormal double-negative T cell morphology_Tg(ITGAL-Hhex)2Hro/0
  http://metadb.riken.jp/0002407C3HeBFeJTgITGALHhex2HroTgITGALHhex2Hro0TgITGALHhex2Hro
• thymus hypoplasia_Tg(ITGAL-Hhex)2Hro/0
  http://metadb.riken.jp/0001823C3HeBFeJTgITGALHhex2HroTgITGALHhex2Hro0TgITGALHhex2Hro
• decreased leukocyte cell number_Tg(Lck-Hhex)1Hro/0
  http://metadb.riken.jp/0000221C3HeBFeJTgLckHhex1HroTgLckHhex1Hro0TgLckHhex1Hro
• increased erythroid progenitor cell number_Tg(ITGAL-Hhex)2Hro/0
  http://metadb.riken.jp/0003135C3HeBFeJTgITGALHhex2HroTgITGALHhex2Hro0TgITGALHhex2Hro
• decreased T cell number_Tg(ITGAL-Hhex)2Hro/0
  http://metadb.riken.jp/0005018C3HeBFeJTgITGALHhex2HroTgITGALHhex2Hro0TgITGALHhex2Hro
• abnormal common myeloid progenitor cell morphology_Tg(ITGAL-Hhex)2Hro/0
  http://metadb.riken.jp/0006410C3HeBFeJTgITGALHhex2HroTgITGALHhex2Hro0TgITGALHhex2Hro
• decreased double-positive T cell number_Tg(ITGAL-Hhex)2Hro/0
  http://metadb.riken.jp/0005092C3HeBFeJTgITGALHhex2HroTgITGALHhex2Hro0TgITGALHhex2Hro
• abnormal thymus corticomedullary boundary morphology_Tg(ITGAL-Hhex)2Hro/0
  http://metadb.riken.jp/0009543C3HeBFeJTgITGALHhex2HroTgITGALHhex2Hro0TgITGALHhex2Hro
• thymus hyperplasia_Tg(Lck-Hhex)1Hro/0
  http://metadb.riken.jp/0000708C3HeBFeJTgLckHhex1HroTgLckHhex1Hro0TgLckHhex1Hro
• decreased leukocyte cell number_Tg(ITGAL-Hhex)2Hro/0
  http://metadb.riken.jp/0000221C3HeBFeJTgITGALHhex2HroTgITGALHhex2Hro0TgITGALHhex2Hro
• decreased lymphocyte cell number_Tg(Lck-Hhex)1Hro/0
  http://metadb.riken.jp/0005016C3HeBFeJTgLckHhex1HroTgLckHhex1Hro0TgLckHhex1Hro
• decreased lymphocyte cell number_Tg(ITGAL-Hhex)2Hro/0
  http://metadb.riken.jp/0005016C3HeBFeJTgITGALHhex2HroTgITGALHhex2Hro0TgITGALHhex2Hro
• decreased double-positive T cell number_Tg(Lck-Hhex)1Hro/0
  http://metadb.riken.jp/0005092C3HeBFeJTgLckHhex1HroTgLckHhex1Hro0TgLckHhex1Hro
• increased CD8-positive, alpha-beta T cell number_Tg(Lck-Hhex)1Hro/0
  http://metadb.riken.jp/0008078C3HeBFeJTgLckHhex1HroTgLckHhex1Hro0TgLckHhex1Hro