Michael. Gotthardt, et.al., Conditional expression of mutant M-line titins results in cardiomyopathy with altered sarcomere structure., The Journal of biological chemistry, 2003, 278

http://rdf.ncbi.nlm.nih.gov/pubmed/12464612

Michael. Gotthardt, et.al., Conditional expression of mutant M-line titins results in cardiomyopathy with altered sarcomere structure., The Journal of biological chemistry, 2003, 278

pubmed

allele

http://purl.org/net/cito/citesAsAuthority

• Ttn<tm1Her>
  http://metadb.riken.jp/db/mgi_rdf/MGI:2651645

class

http://purl.org/net/cito/citesAsAuthority

• Ttn<tm1Her>
  http://metadb.riken.jp/db/mgi_rdf/MGI:2651645

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• decreased body size_Ttn<tm1Her>/Ttn<tm1Her>,Tg(Ckmm-cre)5Khn/0
  http://metadb.riken.jp/0001265NSTtntm1HerTtntm1HerTgCkmmcre5Khn0TgCkmmcre5KhnTtntm1Her
• abnormal sarcomere morphology_Ttn<tm1Her>/Ttn<tm1Her>,Tg(Ckmm-cre)5Khn/0
  http://metadb.riken.jp/0004090NSTtntm1HerTtntm1HerTgCkmmcre5Khn0TgCkmmcre5KhnTtntm1Her
• abnormal gait_Ttn<tm1Her>/Ttn<tm1Her>,Tg(Ckmm-cre)5Khn/0
  http://metadb.riken.jp/0001406NSTtntm1HerTtntm1HerTgCkmmcre5Khn0TgCkmmcre5KhnTtntm1Her
• abnormal M lines_Ttn<tm1Her>/Ttn<tm1Her>,Tg(Ckmm-cre)5Khn/0
  http://metadb.riken.jp/0004094NSTtntm1HerTtntm1HerTgCkmmcre5Khn0TgCkmmcre5KhnTtntm1Her
• premature death_Ttn<tm1Her>/Ttn<tm1Her>,Tg(Ckmm-cre)5Khn/0
  http://metadb.riken.jp/0002083NSTtntm1HerTtntm1HerTgCkmmcre5Khn0TgCkmmcre5KhnTtntm1Her
• progressive muscle weakness_Ttn<tm1Her>/Ttn<tm1Her>,Tg(Ckmm-cre)5Khn/0
  http://metadb.riken.jp/0000748NSTtntm1HerTtntm1HerTgCkmmcre5Khn0TgCkmmcre5KhnTtntm1Her
• postnatal growth retardation_Ttn<tm1Her>/Ttn<tm1Her>,Tg(Ckmm-cre)5Khn/0
  http://metadb.riken.jp/0001732NSTtntm1HerTtntm1HerTgCkmmcre5Khn0TgCkmmcre5KhnTtntm1Her
• blepharoptosis_Ttn<tm1Her>/Ttn<tm1Her>,Tg(Ckmm-cre)5Khn/0
  http://metadb.riken.jp/0001344NSTtntm1HerTtntm1HerTgCkmmcre5Khn0TgCkmmcre5KhnTtntm1Her
• lethality throughout fetal growth and development, complete penetrance_Ttn<tm1Her>/Ttn<tm1Her>,Tg(Myh6-cre)2182Mds/0
  http://metadb.riken.jp/0011099NSTtntm1HerTtntm1HerTgMyh6cre2182Mds0TgMyh6cre2182MdsTtntm1Her
• no abnormal phenotype detected_Ttn<tm1Her>/Ttn<tm1Her>
  http://metadb.riken.jp/0002169NSTtntm1HerTtntm1HerTtntm1Her
• abnormal posture_Ttn<tm1Her>/Ttn<tm1Her>,Tg(Ckmm-cre)5Khn/0
  http://metadb.riken.jp/0001504NSTtntm1HerTtntm1HerTgCkmmcre5Khn0TgCkmmcre5KhnTtntm1Her
• no abnormal phenotype detected_Ttn<tm1Her>/Ttn<+>
  http://metadb.riken.jp/0002169NSTtntm1HerTtnTtnTtntm1Her