Jörg R. Leheste, et.al., Hypocalcemia and osteopathy in mice with kidney-specific megalin gene defect., FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 2003, 17

http://rdf.ncbi.nlm.nih.gov/pubmed/12475886

Jörg R. Leheste, et.al., Hypocalcemia and osteopathy in mice with kidney-specific megalin gene defect., FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 2003, 17

pubmed

allele

http://purl.org/net/cito/citesAsAuthority

• Tg(APOE-cre)VITew
  http://metadb.riken.jp/db/mgi_rdf/MGI:2449766
• Lrp2<tm1Tew>
  http://metadb.riken.jp/db/mgi_rdf/MGI:2449765

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• increased urine protein level_Lrp2<tm1Tew>/Lrp2<tm1Tew>,Tg(APOE-cre)VITew/0
  http://metadb.riken.jp/0002962NSLrp2tm1TewLrp2tm1TewTgAPOEcreVITew0TgAPOEcreVITewLrp2tm1Tew
• abnormal bone remodeling_Lrp2<tm1Tew>/Lrp2<tm1Tew>,Tg(APOE-cre)VITew/0
  http://metadb.riken.jp/0002998NSLrp2tm1TewLrp2tm1TewTgAPOEcreVITew0TgAPOEcreVITewLrp2tm1Tew
• abnormal vitamin D level_Lrp2<tm1Tew>/Lrp2<tm1Tew>,Tg(APOE-cre)VITew/0
  http://metadb.riken.jp/0011228NSLrp2tm1TewLrp2tm1TewTgAPOEcreVITew0TgAPOEcreVITewLrp2tm1Tew
• decreased circulating calcium level_Lrp2<tm1Tew>/Lrp2<tm1Tew>,Tg(APOE-cre)VITew/0
  http://metadb.riken.jp/0000195NSLrp2tm1TewLrp2tm1TewTgAPOEcreVITew0TgAPOEcreVITewLrp2tm1Tew
• increased bone resorption_Lrp2<tm1Tew>/Lrp2<tm1Tew>,Tg(APOE-cre)VITew/0
  http://metadb.riken.jp/0004992NSLrp2tm1TewLrp2tm1TewTgAPOEcreVITew0TgAPOEcreVITewLrp2tm1Tew
• increased circulating parathyroid hormone level_Lrp2<tm1Tew>/Lrp2<tm1Tew>,Tg(APOE-cre)VITew/0
  http://metadb.riken.jp/0002904NSLrp2tm1TewLrp2tm1TewTgAPOEcreVITew0TgAPOEcreVITewLrp2tm1Tew
• abnormal urine homeostasis_Lrp2<tm1Tew>/Lrp2<tm1Tew>,Tg(APOE-cre)VITew/0
  http://metadb.riken.jp/0009643NSLrp2tm1TewLrp2tm1TewTgAPOEcreVITew0TgAPOEcreVITewLrp2tm1Tew
• decreased bone mineral content_Lrp2<tm1Tew>/Lrp2<tm1Tew>,Tg(APOE-cre)VITew/0
  http://metadb.riken.jp/0010124NSLrp2tm1TewLrp2tm1TewTgAPOEcreVITew0TgAPOEcreVITewLrp2tm1Tew
• osteomalacia_Lrp2<tm1Tew>/Lrp2<tm1Tew>,Tg(APOE-cre)VITew/0
  http://metadb.riken.jp/0009445NSLrp2tm1TewLrp2tm1TewTgAPOEcreVITew0TgAPOEcreVITewLrp2tm1Tew
• abnormal bone mineralization_Lrp2<tm1Tew>/Lrp2<tm1Tew>,Tg(APOE-cre)VITew/0
  http://metadb.riken.jp/0002896NSLrp2tm1TewLrp2tm1TewTgAPOEcreVITew0TgAPOEcreVITewLrp2tm1Tew
• decreased bone mineral content_Lrp2<tm1Tew>/Lrp2<tm1Tew>
  http://metadb.riken.jp/0010124NSLrp2tm1TewLrp2tm1TewLrp2tm1Tew

class

http://purl.org/net/cito/citesAsAuthority

• Tg(APOE-cre)VITew
  http://metadb.riken.jp/db/mgi_rdf/MGI:2449766
• Lrp2<tm1Tew>
  http://metadb.riken.jp/db/mgi_rdf/MGI:2449765