Susan M. Mendrysa, et.al., mdm2 Is critical for inhibition of p53 during lymphopoiesis and the response to ionizing irradiation., Molecular and cellular biology, 2003, 23

http://rdf.ncbi.nlm.nih.gov/pubmed/12509446

Susan M. Mendrysa, et.al., mdm2 Is critical for inhibition of p53 during lymphopoiesis and the response to ionizing irradiation., Molecular and cellular biology, 2003, 23

pubmed

allele

http://purl.org/net/cito/citesAsAuthority

• Mdm2<tm1.2Mep>
  http://metadb.riken.jp/db/mgi_rdf/MGI:2673930
• Mdm2<tm1Mep>
  http://metadb.riken.jp/db/mgi_rdf/MGI:2673927
• Mdm2<tm1.1Mep>
  http://metadb.riken.jp/db/mgi_rdf/MGI:2673928

class

http://purl.org/net/cito/citesAsAuthority

• Mdm2<tm1.2Mep>
  http://metadb.riken.jp/db/mgi_rdf/MGI:2673930
• Mdm2<tm1Mep>
  http://metadb.riken.jp/db/mgi_rdf/MGI:2673927
• Mdm2<tm1.1Mep>
  http://metadb.riken.jp/db/mgi_rdf/MGI:2673928

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• decreased thymocyte number_Mdm2<tm1Bay>/Mdm2<tm1Mep>
  http://metadb.riken.jp/0000715I129S7SvEvBrdC57BL6Mdm2tm1BayMdm2tm1MepMdm2tm1MepMdm2tm1Bay
• decreased body weight_Mdm2<tm1Mep>/Mdm2<tm1.1Mep>
  http://metadb.riken.jp/0001262I129S7SvEvBrdC57BL6FVBMdm2tm1MepMdm2tm11MepMdm2tm11MepMdm2tm1Mep
• decreased spleen weight_Mdm2<tm1Bay>/Mdm2<tm1Mep>
  http://metadb.riken.jp/0004953I129S7SvEvBrdC57BL6Mdm2tm1BayMdm2tm1MepMdm2tm1MepMdm2tm1Bay
• prenatal lethality, incomplete penetrance_Mdm2<tm1Bay>/Mdm2<tm1Mep>
  http://metadb.riken.jp/0011101I129S7SvEvBrdC57BL6Mdm2tm1BayMdm2tm1MepMdm2tm1MepMdm2tm1Bay
• decreased immature B cell number_Mdm2<tm1Bay>/Mdm2<tm1Mep>
  http://metadb.riken.jp/0008215I129S7SvEvBrdC57BL6Mdm2tm1BayMdm2tm1MepMdm2tm1MepMdm2tm1Bay
• decreased neutrophil cell number_Mdm2<tm1Bay>/Mdm2<tm1Mep>
  http://metadb.riken.jp/0000222I129S7SvEvBrdC57BL6Mdm2tm1BayMdm2tm1MepMdm2tm1MepMdm2tm1Bay
• decreased spleen weight_Mdm2<tm1Mep>/Mdm2<tm1.1Mep>
  http://metadb.riken.jp/0004953I129S7SvEvBrdC57BL6FVBMdm2tm1MepMdm2tm11MepMdm2tm11MepMdm2tm1Mep
• decreased kidney weight_Mdm2<tm1Mep>/Mdm2<tm1.1Mep>
  http://metadb.riken.jp/0003918I129S7SvEvBrdC57BL6FVBMdm2tm1MepMdm2tm11MepMdm2tm11MepMdm2tm1Mep
• anemia_Mdm2<tm1Bay>/Mdm2<tm1Mep>
  http://metadb.riken.jp/0001577I129S7SvEvBrdC57BL6Mdm2tm1BayMdm2tm1MepMdm2tm1MepMdm2tm1Bay
• decreased erythrocyte cell number_Mdm2<tm1Bay>/Mdm2<tm1Mep>
  http://metadb.riken.jp/0002875I129S7SvEvBrdC57BL6Mdm2tm1BayMdm2tm1MepMdm2tm1MepMdm2tm1Bay
• increased mortality induced by gamma-irradiation_Mdm2<tm1Mep>/Mdm2<+>
  http://metadb.riken.jp/0001658I129S7SvEvBrdC57BL6Mdm2tm1MepMdm2Mdm2Mdm2tm1Mep
• no abnormal phenotype detected_Mdm2<tm1Bay>/Mdm2<tm1.2Mep>
  http://metadb.riken.jp/0002169I129S7SvEvBrdC57BL6FVBMdm2tm1BayMdm2tm12MepMdm2tm1BayMdm2tm12Mep
• abnormal B cell differentiation_Mdm2<tm1Bay>/Mdm2<tm1Mep>
  http://metadb.riken.jp/0002144I129S7SvEvBrdC57BL6Mdm2tm1BayMdm2tm1MepMdm2tm1MepMdm2tm1Bay
• abnormal cell cycle checkpoint function_Mdm2<tm1Bay>/Mdm2<tm1Mep>
  http://metadb.riken.jp/0004045I129S7SvEvBrdC57BL6Mdm2tm1BayMdm2tm1MepMdm2tm1MepMdm2tm1Bay
• decreased lymphocyte cell number_Mdm2<tm1Bay>/Mdm2<tm1Mep>
  http://metadb.riken.jp/0005016I129S7SvEvBrdC57BL6Mdm2tm1BayMdm2tm1MepMdm2tm1MepMdm2tm1Bay
• decreased liver weight_Mdm2<tm1Bay>/Mdm2<tm1Mep>
  http://metadb.riken.jp/0003402I129S7SvEvBrdC57BL6Mdm2tm1BayMdm2tm1MepMdm2tm1MepMdm2tm1Bay
• decreased double-positive T cell number_Mdm2<tm1Bay>/Mdm2<tm1Mep>
  http://metadb.riken.jp/0005092I129S7SvEvBrdC57BL6Mdm2tm1BayMdm2tm1MepMdm2tm1MepMdm2tm1Bay
• decreased cell proliferation_Mdm2<tm1Bay>/Mdm2<tm1Mep>
  http://metadb.riken.jp/0000352I129S7SvEvBrdC57BL6Mdm2tm1BayMdm2tm1MepMdm2tm1MepMdm2tm1Bay
• decreased body weight_Mdm2<tm1Bay>/Mdm2<tm1Mep>
  http://metadb.riken.jp/0001262I129S7SvEvBrdC57BL6Mdm2tm1BayMdm2tm1MepMdm2tm1MepMdm2tm1Bay
• decreased kidney weight_Mdm2<tm1Bay>/Mdm2<tm1Mep>
  http://metadb.riken.jp/0003918I129S7SvEvBrdC57BL6Mdm2tm1BayMdm2tm1MepMdm2tm1MepMdm2tm1Bay
• prenatal lethality, complete penetrance_Mdm2<tm1Bay>/Mdm2<tm1.1Mep>
  http://metadb.riken.jp/0011091I129S7SvEvBrdC57BL6FVBMdm2tm1BayMdm2tm11MepMdm2tm11MepMdm2tm1Bay
• decreased granulocyte number_Mdm2<tm1Bay>/Mdm2<tm1Mep>
  http://metadb.riken.jp/0000334I129S7SvEvBrdC57BL6Mdm2tm1BayMdm2tm1MepMdm2tm1MepMdm2tm1Bay
• decreased mortality induced by ionizing radiation_Mdm2<tm1Bay>/Mdm2<tm1Mep>,Trp53<tm1Tyj>/Trp53<tm1Tyj>
  http://metadb.riken.jp/0003010I129S2SvPas129S7SvEvBrdC57BL6Mdm2tm1BayMdm2tm1MepTrp53tm1TyjTrp53tm1TyjTrp53tm1TyjMdm2tm1MepMdm2tm1Bay
• decreased bone marrow cell number_Mdm2<tm1Bay>/Mdm2<tm1Mep>
  http://metadb.riken.jp/0000333I129S7SvEvBrdC57BL6Mdm2tm1BayMdm2tm1MepMdm2tm1MepMdm2tm1Bay
• decreased thymus weight_Mdm2<tm1Mep>/Mdm2<tm1.1Mep>
  http://metadb.riken.jp/0004956I129S7SvEvBrdC57BL6FVBMdm2tm1MepMdm2tm11MepMdm2tm11MepMdm2tm1Mep
• abnormal bone marrow cell morphology/development_Mdm2<tm1Bay>/Mdm2<tm1Mep>,Trp53<tm1Tyj>/Trp53<tm1Tyj>
  http://metadb.riken.jp/0002398I129S2SvPas129S7SvEvBrdC57BL6Mdm2tm1BayMdm2tm1MepTrp53tm1TyjTrp53tm1TyjTrp53tm1TyjMdm2tm1MepMdm2tm1Bay
• thymus hypoplasia_Mdm2<tm1Bay>/Mdm2<tm1Mep>
  http://metadb.riken.jp/0001823I129S7SvEvBrdC57BL6Mdm2tm1BayMdm2tm1MepMdm2tm1MepMdm2tm1Bay
• increased cellular sensitivity to ionizing radiation_Mdm2<tm1Bay>/Mdm2<tm1Mep>
  http://metadb.riken.jp/0004227I129S7SvEvBrdC57BL6Mdm2tm1BayMdm2tm1MepMdm2tm1MepMdm2tm1Bay
• increased mortality induced by gamma-irradiation_Mdm2<tm1Bay>/Mdm2<+>
  http://metadb.riken.jp/0001658B6129S7Mdm2tm1BayMdm2tm1BayMdm2Mdm2tm1BayMdm2
• decreased double-negative T cell number_Mdm2<tm1Bay>/Mdm2<tm1Mep>
  http://metadb.riken.jp/0005089I129S7SvEvBrdC57BL6Mdm2tm1BayMdm2tm1MepMdm2tm1MepMdm2tm1Bay
• decreased leukocyte cell number_Mdm2<tm1Bay>/Mdm2<tm1Mep>
  http://metadb.riken.jp/0000221I129S7SvEvBrdC57BL6Mdm2tm1BayMdm2tm1MepMdm2tm1MepMdm2tm1Bay
• decreased liver weight_Mdm2<tm1Mep>/Mdm2<tm1.1Mep>
  http://metadb.riken.jp/0003402I129S7SvEvBrdC57BL6FVBMdm2tm1MepMdm2tm11MepMdm2tm11MepMdm2tm1Mep
• decreased thymus weight_Mdm2<tm1Bay>/Mdm2<tm1Mep>
  http://metadb.riken.jp/0004956I129S7SvEvBrdC57BL6Mdm2tm1BayMdm2tm1MepMdm2tm1MepMdm2tm1Bay
• abnormal small intestine morphology_Mdm2<tm1Bay>/Mdm2<tm1Mep>,Trp53<tm1Tyj>/Trp53<tm1Tyj>
  http://metadb.riken.jp/0000496I129S2SvPas129S7SvEvBrdC57BL6Mdm2tm1BayMdm2tm1MepTrp53tm1TyjTrp53tm1TyjTrp53tm1TyjMdm2tm1MepMdm2tm1Bay
• decreased T cell number_Mdm2<tm1Bay>/Mdm2<tm1Mep>
  http://metadb.riken.jp/0005018I129S7SvEvBrdC57BL6Mdm2tm1BayMdm2tm1MepMdm2tm1MepMdm2tm1Bay
• spleen hypoplasia_Mdm2<tm1Bay>/Mdm2<tm1Mep>
  http://metadb.riken.jp/0000694I129S7SvEvBrdC57BL6Mdm2tm1BayMdm2tm1MepMdm2tm1MepMdm2tm1Bay
• prenatal lethality, complete penetrance_Mdm2<tm1.1Mep>/Mdm2<tm1.1Mep>
  http://metadb.riken.jp/0011091I129S7SvEvBrdC57BL6Mdm2tm11MepMdm2tm11MepMdm2tm11Mep