Pablo A. Silveira, et.al., The preferential ability of B lymphocytes to act as diabetogenic APC in NOD mice depends on expression of self-antigen-specific immunoglobulin receptors., European journal of immunology, 2002, 32

http://rdf.ncbi.nlm.nih.gov/pubmed/12516557

Pablo A. Silveira, et.al., The preferential ability of B lymphocytes to act as diabetogenic APC in NOD mice depends on expression of self-antigen-specific immunoglobulin receptors., European journal of immunology, 2002, 32

pubmed

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• decreased CD8-positive, alpha-beta T cell number_Tg(IghelMD4)4Ccg/Tg(IghelMD4)4Ccg
  http://metadb.riken.jp/0008079NODB6TgIghelMD44CcgDvsJTgIghelMD44CcgTgIghelMD44CcgTgIghelMD44Ccg
• decreased susceptibility to autoimmune diabetes_Ighm<tm1Cgn>/Ighm<tm1Cgn>,Tg(IghelMD4)4Ccg/Tg(IghelMD4)4Ccg
  http://metadb.riken.jp/0004804NODCgIghmtm1CgnTgIghelMD44CcgDvsJIghmtm1CgnIghmtm1CgnTgIghelMD44CcgTgIghelMD44CcgTgIghelMD44CcgIghmtm1Cgn
• abnormal T cell number_Ighm<tm1Cgn>/Ighm<tm1Cgn>
  http://metadb.riken.jp/0006387NOD129S2Ighmtm1CgnDvsJIghmtm1CgnIghmtm1CgnIghmtm1Cgn
• abnormal B lymphocyte antigen presentation_Ighm<tm1Cgn>/Ighm<tm1Cgn>,Tg(IghelMD4)4Ccg/Tg(IghelMD4)4Ccg
  http://metadb.riken.jp/0002453NODCgIghmtm1CgnTgIghelMD44CcgDvsJIghmtm1CgnIghmtm1CgnTgIghelMD44CcgTgIghelMD44CcgTgIghelMD44CcgIghmtm1Cgn
• abnormal spleen B cell follicle morphology_Ighm<tm1Cgn>/Ighm<tm1Cgn>
  http://metadb.riken.jp/0008470NOD129S2Ighmtm1CgnDvsJIghmtm1CgnIghmtm1CgnIghmtm1Cgn
• abnormal T cell proliferation_Tg(IghelMD4)4Ccg/Tg(IghelMD4)4Ccg
  http://metadb.riken.jp/0005094NODB6TgIghelMD44CcgDvsJTgIghelMD44CcgTgIghelMD44CcgTgIghelMD44Ccg
• abnormal T cell proliferation_Ighm<tm1Cgn>/Ighm<tm1Cgn>
  http://metadb.riken.jp/0005094NOD129S2Ighmtm1CgnDvsJIghmtm1CgnIghmtm1CgnIghmtm1Cgn
• absent B cells_Ighm<tm1Cgn>/Ighm<tm1Cgn>
  http://metadb.riken.jp/0008071NOD129S2Ighmtm1CgnDvsJIghmtm1CgnIghmtm1CgnIghmtm1Cgn
• insulitis_Ighm<tm1Cgn>/Ighm<tm1Cgn>,Tg(IghelMD4)4Ccg/Tg(IghelMD4)4Ccg
  http://metadb.riken.jp/0004031NODCgIghmtm1CgnTgIghelMD44CcgDvsJIghmtm1CgnIghmtm1CgnTgIghelMD44CcgTgIghelMD44CcgTgIghelMD44CcgIghmtm1Cgn
• increased susceptibility to autoimmune diabetes_Tg(IghelMD4)4Ccg/Tg(IghelMD4)4Ccg
  http://metadb.riken.jp/0004803NODB6TgIghelMD44CcgDvsJTgIghelMD44CcgTgIghelMD44CcgTgIghelMD44Ccg
• decreased susceptibility to autoimmune diabetes_Ighm<tm1Cgn>/Ighm<tm1Cgn>
  http://metadb.riken.jp/0004804NOD129S2Ighmtm1CgnDvsJIghmtm1CgnIghmtm1CgnIghmtm1Cgn
• decreased CD8-positive, alpha-beta T cell number_Ighm<tm1Cgn>/Ighm<tm1Cgn>,Tg(IghelMD4)4Ccg/Tg(IghelMD4)4Ccg
  http://metadb.riken.jp/0008079NODCgIghmtm1CgnTgIghelMD44CcgDvsJIghmtm1CgnIghmtm1CgnTgIghelMD44CcgTgIghelMD44CcgTgIghelMD44CcgIghmtm1Cgn
• abnormal T cell proliferation_Ighm<tm1Cgn>/Ighm<tm1Cgn>,Tg(IghelMD4)4Ccg/Tg(IghelMD4)4Ccg
  http://metadb.riken.jp/0005094NODCgIghmtm1CgnTgIghelMD44CcgDvsJIghmtm1CgnIghmtm1CgnTgIghelMD44CcgTgIghelMD44CcgTgIghelMD44CcgIghmtm1Cgn
• abnormal mature B cell morphology_Ighm<tm1Cgn>/Ighm<tm1Cgn>,Tg(IghelMD4)4Ccg/Tg(IghelMD4)4Ccg
  http://metadb.riken.jp/0008171NODCgIghmtm1CgnTgIghelMD44CcgDvsJIghmtm1CgnIghmtm1CgnTgIghelMD44CcgTgIghelMD44CcgTgIghelMD44CcgIghmtm1Cgn
• abnormal mature B cell morphology_Tg(IghelMD4)4Ccg/Tg(IghelMD4)4Ccg
  http://metadb.riken.jp/0008171NODB6TgIghelMD44CcgDvsJTgIghelMD44CcgTgIghelMD44CcgTgIghelMD44Ccg
• increased lymphoma incidence_Ighm<tm1Cgn>/Ighm<tm1Cgn>,Tg(IghelMD4)4Ccg/Tg(IghelMD4)4Ccg
  http://metadb.riken.jp/0012431NODCgIghmtm1CgnTgIghelMD44CcgDvsJIghmtm1CgnIghmtm1CgnTgIghelMD44CcgTgIghelMD44CcgTgIghelMD44CcgIghmtm1Cgn

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• abnormal T cell proliferation in RBRC05550
  http://metadb.riken.jp/db/rikenbrc_mouse/Phenotype_1008456
• abnormal spleen B cell follicle morphology in RBRC05550
  http://metadb.riken.jp/db/rikenbrc_mouse/Phenotype_1008471
• abnormal T cell number in RBRC05550
  http://metadb.riken.jp/db/rikenbrc_mouse/Phenotype_1008461
• absent B cells in RBRC05550
  http://metadb.riken.jp/db/rikenbrc_mouse/Phenotype_1008462
• decreased susceptibility to autoimmune diabetes in RBRC05550
  http://metadb.riken.jp/db/rikenbrc_mouse/Phenotype_1010779