Davide. Ruggero, et.al., Dyskeratosis congenita and cancer in mice deficient in ribosomal RNA modification., Science (New York, N.Y.), 2003, 299

http://rdf.ncbi.nlm.nih.gov/pubmed/12522253

Davide. Ruggero, et.al., Dyskeratosis congenita and cancer in mice deficient in ribosomal RNA modification., Science (New York, N.Y.), 2003, 299

pubmed

allele

http://purl.org/net/cito/citesAsAuthority

• Dkc1<tm1Ppp>
  http://metadb.riken.jp/db/mgi_rdf/MGI:2449175

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• increased mammary adenocarcinoma incidence_Dkc1<tm1Ppp>/Y
  http://metadb.riken.jp/0001883I129S1SvDkc1tm1PppYDkc1tm1Ppp
• increased pheochromocytoma incidence_Dkc1<tm1Ppp>/Y
  http://metadb.riken.jp/0002050I129S1SvDkc1tm1PppYDkc1tm1Ppp
• abnormal immune system organ morphology_Dkc1<tm1Ppp>/Dkc1<+>
  http://metadb.riken.jp/0002722I129S1SvDkc1tm1PppDkc1Dkc1Dkc1tm1Ppp
• increased B cell derived lymphoma incidence_Dkc1<tm1Ppp>/Y
  http://metadb.riken.jp/0002023I129S1SvDkc1tm1PppYDkc1tm1Ppp
• abnormal spleen morphology_Dkc1<tm1Ppp>/Y
  http://metadb.riken.jp/0000689I129S1SvDkc1tm1PppYDkc1tm1Ppp
• glomerulosclerosis_Dkc1<tm1Ppp>/Y
  http://metadb.riken.jp/0005264I129S1SvDkc1tm1PppYDkc1tm1Ppp
• dyskeratosis_Dkc1<tm1Ppp>/Y
  http://metadb.riken.jp/0009563I129S1SvDkc1tm1PppYDkc1tm1Ppp
• abnormal skin morphology_Dkc1<tm1Ppp>/Dkc1<+>
  http://metadb.riken.jp/0002060I129S1SvDkc1tm1PppDkc1Dkc1Dkc1tm1Ppp
• increased renal carcinoma incidence_Dkc1<tm1Ppp>/Y
  http://metadb.riken.jp/0010384I129S1SvDkc1tm1PppYDkc1tm1Ppp
• increased malignant tumor incidence_Dkc1<tm1Ppp>/Y
  http://metadb.riken.jp/0002018I129S1SvDkc1tm1PppYDkc1tm1Ppp
• decreased lymphocyte cell number_Dkc1<tm1Ppp>/Y
  http://metadb.riken.jp/0005016I129S1SvDkc1tm1PppYDkc1tm1Ppp
• renal tubule atrophy_Dkc1<tm1Ppp>/Y
  http://metadb.riken.jp/0011346I129S1SvDkc1tm1PppYDkc1tm1Ppp
• abnormal definitive hematopoiesis_Dkc1<tm1Ppp>/Dkc1<+>
  http://metadb.riken.jp/0002123I129S1SvDkc1tm1PppDkc1Dkc1Dkc1tm1Ppp
• abnormal cell morphology_Dkc1<tm1Ppp>/Dkc1<+>
  http://metadb.riken.jp/0000358I129S1SvDkc1tm1PppDkc1Dkc1Dkc1tm1Ppp
• abnormal cell physiology_Dkc1<tm1Ppp>/Y
  http://metadb.riken.jp/0005621I129S1SvDkc1tm1PppYDkc1tm1Ppp
• abnormal proximal convoluted tubule morphology_Dkc1<tm1Ppp>/Y
  http://metadb.riken.jp/0004756I129S1SvDkc1tm1PppYDkc1tm1Ppp
• abnormal cell physiology_Dkc1<tm1Ppp>/Dkc1<+>
  http://metadb.riken.jp/0005621I129S1SvDkc1tm1PppDkc1Dkc1Dkc1tm1Ppp
• thrombocytopenia_Dkc1<tm1Ppp>/Y
  http://metadb.riken.jp/0003179I129S1SvDkc1tm1PppYDkc1tm1Ppp
• increased fibrosarcoma incidence_Dkc1<tm1Ppp>/Y
  http://metadb.riken.jp/0010363I129S1SvDkc1tm1PppYDkc1tm1Ppp
• enlarged spleen_Dkc1<tm1Ppp>/Y
  http://metadb.riken.jp/0000691I129S1SvDkc1tm1PppYDkc1tm1Ppp
• extramedullary hematopoiesis_Dkc1<tm1Ppp>/Y
  http://metadb.riken.jp/0000240I129S1SvDkc1tm1PppYDkc1tm1Ppp
• decreased spleen red pulp amount_Dkc1<tm1Ppp>/Y
  http://metadb.riken.jp/0008477I129S1SvDkc1tm1PppYDkc1tm1Ppp
• lung inflammation_Dkc1<tm1Ppp>/Y
  http://metadb.riken.jp/0001861I129S1SvDkc1tm1PppYDkc1tm1Ppp
• anemia_Dkc1<tm1Ppp>/Y
  http://metadb.riken.jp/0001577I129S1SvDkc1tm1PppYDkc1tm1Ppp
• abnormal erythrocyte morphology_Dkc1<tm1Ppp>/Dkc1<+>
  http://metadb.riken.jp/0002447I129S1SvDkc1tm1PppDkc1Dkc1Dkc1tm1Ppp
• abnormal bone marrow cell morphology/development_Dkc1<tm1Ppp>/Dkc1<+>
  http://metadb.riken.jp/0002398I129S1SvDkc1tm1PppDkc1Dkc1Dkc1tm1Ppp
• abnormal hematopoietic system physiology_Dkc1<tm1Ppp>/Dkc1<+>
  http://metadb.riken.jp/0001545I129S1SvDkc1tm1PppDkc1Dkc1Dkc1tm1Ppp
• epidermal hyperplasia_Dkc1<tm1Ppp>/Y
  http://metadb.riken.jp/0001222I129S1SvDkc1tm1PppYDkc1tm1Ppp
• decreased erythroid progenitor cell number_Dkc1<tm1Ppp>/Y
  http://metadb.riken.jp/0008973I129S1SvDkc1tm1PppYDkc1tm1Ppp
• abnormal definitive hematopoiesis_Dkc1<tm1Ppp>/Y
  http://metadb.riken.jp/0002123I129S1SvDkc1tm1PppYDkc1tm1Ppp
• decreased leukocyte cell number_Dkc1<tm1Ppp>/Y
  http://metadb.riken.jp/0000221I129S1SvDkc1tm1PppYDkc1tm1Ppp
• increased tumor incidence_Dkc1<tm1Ppp>/Dkc1<+>
  http://metadb.riken.jp/0002020I129S1SvDkc1tm1PppDkc1Dkc1Dkc1tm1Ppp
• decreased spleen white pulp amount_Dkc1<tm1Ppp>/Y
  http://metadb.riken.jp/0008479I129S1SvDkc1tm1PppYDkc1tm1Ppp
• abnormal epidermis stratum spinosum morphology_Dkc1<tm1Ppp>/Y
  http://metadb.riken.jp/0001236I129S1SvDkc1tm1PppYDkc1tm1Ppp
• abnormal kidney morphology_Dkc1<tm1Ppp>/Dkc1<+>
  http://metadb.riken.jp/0002135I129S1SvDkc1tm1PppDkc1Dkc1Dkc1tm1Ppp
• abnormal bone marrow cell physiology_Dkc1<tm1Ppp>/Y
  http://metadb.riken.jp/0009278I129S1SvDkc1tm1PppYDkc1tm1Ppp
• abnormal lung morphology_Dkc1<tm1Ppp>/Dkc1<+>
  http://metadb.riken.jp/0001175I129S1SvDkc1tm1PppDkc1Dkc1Dkc1tm1Ppp
• increased total body fat amount_Dkc1<tm1Ppp>/Y
  http://metadb.riken.jp/0010024I129S1SvDkc1tm1PppYDkc1tm1Ppp
• abnormal pulmonary alveolus morphology_Dkc1<tm1Ppp>/Y
  http://metadb.riken.jp/0002270I129S1SvDkc1tm1PppYDkc1tm1Ppp
• pulmonary interstitial fibrosis_Dkc1<tm1Ppp>/Y
  http://metadb.riken.jp/0003426I129S1SvDkc1tm1PppYDkc1tm1Ppp
• increased fibroblast apoptosis_Dkc1<tm1Ppp>/Y
  http://metadb.riken.jp/0013501I129S1SvDkc1tm1PppYDkc1tm1Ppp
• abnormal pulmonary alveolar parenchyma morphology_Dkc1<tm1Ppp>/Y
  http://metadb.riken.jp/0010901I129S1SvDkc1tm1PppYDkc1tm1Ppp
• decreased B cell number_Dkc1<tm1Ppp>/Y
  http://metadb.riken.jp/0005017I129S1SvDkc1tm1PppYDkc1tm1Ppp
• abnormal epidermis stratum granulosum morphology_Dkc1<tm1Ppp>/Y
  http://metadb.riken.jp/0001239I129S1SvDkc1tm1PppYDkc1tm1Ppp
• abnormal pulmonary alveolus wall morphology_Dkc1<tm1Ppp>/Y
  http://metadb.riken.jp/0010903I129S1SvDkc1tm1PppYDkc1tm1Ppp
• decreased common myeloid progenitor cell number_Dkc1<tm1Ppp>/Y
  http://metadb.riken.jp/0008813I129S1SvDkc1tm1PppYDkc1tm1Ppp
• abnormal telomere length_Dkc1<tm1Ppp>/Y
  http://metadb.riken.jp/0003155I129S1SvDkc1tm1PppYDkc1tm1Ppp
• increased lung carcinoma incidence_Dkc1<tm1Ppp>/Y
  http://metadb.riken.jp/0008714I129S1SvDkc1tm1PppYDkc1tm1Ppp
• decreased pre-B cell number_Dkc1<tm1Ppp>/Y
  http://metadb.riken.jp/0008209I129S1SvDkc1tm1PppYDkc1tm1Ppp
• decreased bone marrow cell number_Dkc1<tm1Ppp>/Y
  http://metadb.riken.jp/0000333I129S1SvDkc1tm1PppYDkc1tm1Ppp
• decreased hemoglobin content_Dkc1<tm1Ppp>/Y
  http://metadb.riken.jp/0002874I129S1SvDkc1tm1PppYDkc1tm1Ppp
• abnormal immune system cell morphology_Dkc1<tm1Ppp>/Dkc1<+>
  http://metadb.riken.jp/0000716I129S1SvDkc1tm1PppDkc1Dkc1Dkc1tm1Ppp

class

http://purl.org/net/cito/citesAsAuthority

• Dkc1<tm1Ppp>
  http://metadb.riken.jp/db/mgi_rdf/MGI:2449175

トランスクリプトームデータ

http://rdf.ncbi.nlm.nih.gov/pubmed/

• CD10516
  http://metadb.riken.jp/db/BrainTx/TranscriptomeData/CD10516