Irene M. Ward, et.al., p53 Binding protein 53BP1 is required for DNA damage responses and tumor suppression in mice., Molecular and cellular biology, 2003, 23

http://rdf.ncbi.nlm.nih.gov/pubmed/12640136

Irene M. Ward, et.al., p53 Binding protein 53BP1 is required for DNA damage responses and tumor suppression in mice., Molecular and cellular biology, 2003, 23

pubmed

allele

http://purl.org/net/cito/citesAsAuthority

• Trp53bp1<tm1Jc>
  http://metadb.riken.jp/db/mgi_rdf/MGI:2654201

class

http://purl.org/net/cito/citesAsAuthority

• Trp53bp1<tm1Jc>
  http://metadb.riken.jp/db/mgi_rdf/MGI:2654201

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• decreased litter size_Trp53bp1<tm1Jc>/Trp53bp1<tm1Jc>
  http://metadb.riken.jp/0001935I129C57BL6Trp53bp1tm1JcTrp53bp1tm1JcTrp53bp1tm1Jc
• increased mortality induced by ionizing radiation_Trp53bp1<tm1Jc>/Trp53bp1<tm1Jc>
  http://metadb.riken.jp/0003992I129C57BL6Trp53bp1tm1JcTrp53bp1tm1JcTrp53bp1tm1Jc
• decreased body weight_Trp53bp1<tm1Jc>/Trp53bp1<tm1Jc>
  http://metadb.riken.jp/0001262I129C57BL6Trp53bp1tm1JcTrp53bp1tm1JcTrp53bp1tm1Jc
• increased cellular sensitivity to ionizing radiation_Trp53bp1<tm1Jc>/Trp53bp1<tm1Jc>
  http://metadb.riken.jp/0004227I129C57BL6Trp53bp1tm1JcTrp53bp1tm1JcTrp53bp1tm1Jc
• chromosomal instability_Trp53bp1<tm1Jc>/Trp53bp1<tm1Jc>
  http://metadb.riken.jp/0008866I129C57BL6Trp53bp1tm1JcTrp53bp1tm1JcTrp53bp1tm1Jc
• increased lymphoma incidence_Trp53bp1<tm1Jc>/Trp53bp1<tm1Jc>
  http://metadb.riken.jp/0012431I129C57BL6Trp53bp1tm1JcTrp53bp1tm1JcTrp53bp1tm1Jc
• increased double-negative T cell number_Trp53bp1<tm1Jc>/Trp53bp1<tm1Jc>
  http://metadb.riken.jp/0005090I129C57BL6Trp53bp1tm1JcTrp53bp1tm1JcTrp53bp1tm1Jc
• decreased body size_Trp53bp1<tm1Jc>/Trp53bp1<tm1Jc>
  http://metadb.riken.jp/0001265I129C57BL6Trp53bp1tm1JcTrp53bp1tm1JcTrp53bp1tm1Jc
• increased T cell derived lymphoma incidence_Trp53bp1<tm1Jc>/Trp53bp1<tm1Jc>
  http://metadb.riken.jp/0002024I129C57BL6Trp53bp1tm1JcTrp53bp1tm1JcTrp53bp1tm1Jc
• thymus hypoplasia_Trp53bp1<tm1Jc>/Trp53bp1<tm1Jc>
  http://metadb.riken.jp/0001823I129C57BL6Trp53bp1tm1JcTrp53bp1tm1JcTrp53bp1tm1Jc
• abnormal cell cycle checkpoint function_Trp53bp1<tm1Jc>/Trp53bp1<tm1Jc>
  http://metadb.riken.jp/0004045I129C57BL6Trp53bp1tm1JcTrp53bp1tm1JcTrp53bp1tm1Jc
• postnatal growth retardation_Trp53bp1<tm1Jc>/Trp53bp1<tm1Jc>
  http://metadb.riken.jp/0001732I129C57BL6Trp53bp1tm1JcTrp53bp1tm1JcTrp53bp1tm1Jc
• aneuploidy_Trp53bp1<tm1Jc>/Trp53bp1<tm1Jc>
  http://metadb.riken.jp/0004024I129C57BL6Trp53bp1tm1JcTrp53bp1tm1JcTrp53bp1tm1Jc
• decreased cell proliferation_Trp53bp1<tm1Jc>/Trp53bp1<tm1Jc>
  http://metadb.riken.jp/0000352I129C57BL6Trp53bp1tm1JcTrp53bp1tm1JcTrp53bp1tm1Jc
• premature death_Trp53bp1<tm1Jc>/Trp53bp1<tm1Jc>
  http://metadb.riken.jp/0002083I129C57BL6Trp53bp1tm1JcTrp53bp1tm1JcTrp53bp1tm1Jc
• decreased CD4-positive, alpha beta T cell number_Trp53bp1<tm1Jc>/Trp53bp1<tm1Jc>
  http://metadb.riken.jp/0008075I129C57BL6Trp53bp1tm1JcTrp53bp1tm1JcTrp53bp1tm1Jc