Yuichi. Wakabayashi, et.al., Bcl11b is required for differentiation and survival of alphabeta T lymphocytes., Nature immunology, 2003, 4

http://rdf.ncbi.nlm.nih.gov/pubmed/12717433

Yuichi. Wakabayashi, et.al., Bcl11b is required for differentiation and survival of alphabeta T lymphocytes., Nature immunology, 2003, 4

pubmed

allele

http://purl.org/net/cito/citesAsAuthority

• Bcl11b<tm1Jpk>
  http://metadb.riken.jp/db/mgi_rdf/MGI:2663971

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• increased CD8-positive, alpha-beta T cell number_Bcl11b<tm1Jpk>/Bcl11b<tm1Jpk>
  http://metadb.riken.jp/0008078IBALBcC57BL6CBABcl11btm1JpkBcl11btm1JpkBcl11btm1Jpk
• abnormal thymus medulla morphology_Bcl11b<tm1Jpk>/Bcl11b<tm1Jpk>
  http://metadb.riken.jp/0002375IBALBcC57BL6CBABcl11btm1JpkBcl11btm1JpkBcl11btm1Jpk
• abnormal T cell differentiation_Bcl11b<tm1Jpk>/Bcl11b<tm1Jpk>
  http://metadb.riken.jp/0002145IBALBcC57BL6CBABcl11btm1JpkBcl11btm1JpkBcl11btm1Jpk
• thymus hypoplasia_Bcl11b<tm1Jpk>/Bcl11b<tm1Jpk>
  http://metadb.riken.jp/0001823IBALBcC57BL6CBABcl11btm1JpkBcl11btm1JpkBcl11btm1Jpk
• eyelids open at birth_Bcl11b<tm1Jpk>/Bcl11b<tm1Jpk>
  http://metadb.riken.jp/0001302IBALBcC57BL6CBABcl11btm1JpkBcl11btm1JpkBcl11btm1Jpk
• absent thymus corticomedullary boundary_Bcl11b<tm1Jpk>/Bcl11b<tm1Jpk>
  http://metadb.riken.jp/0013741IBALBcC57BL6CBABcl11btm1JpkBcl11btm1JpkBcl11btm1Jpk
• abnormal thymus cortex morphology_Bcl11b<tm1Jpk>/Bcl11b<tm1Jpk>
  http://metadb.riken.jp/0002371IBALBcC57BL6CBABcl11btm1JpkBcl11btm1JpkBcl11btm1Jpk
• increased thymocyte apoptosis_Bcl11b<tm1Jpk>/Bcl11b<tm1Jpk>
  http://metadb.riken.jp/0009541IBALBcC57BL6CBABcl11btm1JpkBcl11btm1JpkBcl11btm1Jpk
• absent gastric milk in neonates_Bcl11b<tm1Jpk>/Bcl11b<tm1Jpk>
  http://metadb.riken.jp/0009546IBALBcC57BL6CBABcl11btm1JpkBcl11btm1JpkBcl11btm1Jpk
• abnormal T cell receptor beta chain V(D)J recombination_Bcl11b<tm1Jpk>/Bcl11b<tm1Jpk>
  http://metadb.riken.jp/0008758IBALBcC57BL6CBABcl11btm1JpkBcl11btm1JpkBcl11btm1Jpk
• decreased double-positive T cell number_Bcl11b<tm1Jpk>/Bcl11b<tm1Jpk>
  http://metadb.riken.jp/0005092IBALBcC57BL6CBABcl11btm1JpkBcl11btm1JpkBcl11btm1Jpk
• neonatal lethality, complete penetrance_Bcl11b<tm1Jpk>/Bcl11b<tm1Jpk>
  http://metadb.riken.jp/0011087IBALBcC57BL6CBABcl11btm1JpkBcl11btm1JpkBcl11btm1Jpk
• increased double-negative T cell number_Bcl11b<tm1Jpk>/Bcl11b<tm1Jpk>
  http://metadb.riken.jp/0005090IBALBcC57BL6CBABcl11btm1JpkBcl11btm1JpkBcl11btm1Jpk
• abnormal T cell morphology_Bcl11b<tm1Jpk>/Bcl11b<tm1Jpk>
  http://metadb.riken.jp/0008037IBALBcC57BL6CBABcl11btm1JpkBcl11btm1JpkBcl11btm1Jpk

class

http://purl.org/net/cito/citesAsAuthority

• Bcl11b<tm1Jpk>
  http://metadb.riken.jp/db/mgi_rdf/MGI:2663971

トランスクリプトームデータ

http://rdf.ncbi.nlm.nih.gov/pubmed/

• CD12549
  http://metadb.riken.jp/db/BrainTx/TranscriptomeData/CD12549

article

http://www.w3.org/2000/01/rdf-schema#seeAlso

• [Blank]
• [Blank]

BRC マウスの系統

http://purl.org/net/cito/citesAsAuthority

• B6.Cg-Bcl11b<tm1Jpk>
  http://metadb.riken.jp/db/rikenbrc_mouse/RBRC06231
• C.Cg-Bcl11b<tm1Jpk>
  http://metadb.riken.jp/db/rikenbrc_mouse/RBRC02421

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• decreased double-positive T cell number in RBRC06231
  http://metadb.riken.jp/db/rikenbrc_mouse/Phenotype_1009628
• neonatal lethality, complete penetrance in RBRC02421
  http://metadb.riken.jp/db/rikenbrc_mouse/Phenotype_1004438
• increased thymocyte apoptosis in RBRC02421
  http://metadb.riken.jp/db/rikenbrc_mouse/Phenotype_1004436
• eyelids open at birth in RBRC02421
  http://metadb.riken.jp/db/rikenbrc_mouse/Phenotype_1004426
• absent thymus corticomedullary boundary in RBRC02421
  http://metadb.riken.jp/db/rikenbrc_mouse/Phenotype_1004439
• absent gastric milk in neonates in RBRC06231
  http://metadb.riken.jp/db/rikenbrc_mouse/Phenotype_1009633
• abnormal T cell receptor beta chain V(D)J recombination in RBRC06231
  http://metadb.riken.jp/db/rikenbrc_mouse/Phenotype_1009631
• abnormal thymus corticomedullary boundary morphology in RBRC06231
  http://metadb.riken.jp/db/rikenbrc_mouse/Phenotype_1014624
• neonatal lethality, complete penetrance in RBRC06231
  http://metadb.riken.jp/db/rikenbrc_mouse/Phenotype_1009634
• abnormal thymus medulla morphology in RBRC06231
  http://metadb.riken.jp/db/rikenbrc_mouse/Phenotype_1009626
• abnormal T cell differentiation in RBRC06231
  http://metadb.riken.jp/db/rikenbrc_mouse/Phenotype_1009624
• abnormal T cell morphology in RBRC06231
  http://metadb.riken.jp/db/rikenbrc_mouse/Phenotype_1009629
• increased double-negative T cell number in RBRC06231
  http://metadb.riken.jp/db/rikenbrc_mouse/Phenotype_1009627
• decreased double-positive T cell number in RBRC02421
  http://metadb.riken.jp/db/rikenbrc_mouse/Phenotype_1004432
• increased CD8-positive, alpha-beta T cell number in RBRC06231
  http://metadb.riken.jp/db/rikenbrc_mouse/Phenotype_1009630
• increased CD8-positive, alpha-beta T cell number in RBRC02421
  http://metadb.riken.jp/db/rikenbrc_mouse/Phenotype_1004434
• absent gastric milk in neonates in RBRC02421
  http://metadb.riken.jp/db/rikenbrc_mouse/Phenotype_1004437
• abnormal T cell receptor beta chain V(D)J recombination in RBRC02421
  http://metadb.riken.jp/db/rikenbrc_mouse/Phenotype_1004435
• abnormal thymus cortex morphology in RBRC02421
  http://metadb.riken.jp/db/rikenbrc_mouse/Phenotype_1004429
• increased thymocyte apoptosis in RBRC06231
  http://metadb.riken.jp/db/rikenbrc_mouse/Phenotype_1009632
• eyelids open at birth in RBRC06231
  http://metadb.riken.jp/db/rikenbrc_mouse/Phenotype_1009622
• abnormal thymus cortex morphology in RBRC06231
  http://metadb.riken.jp/db/rikenbrc_mouse/Phenotype_1009625
• thymus hypoplasia in RBRC06231
  http://metadb.riken.jp/db/rikenbrc_mouse/Phenotype_1009623
• abnormal thymus corticomedullary boundary morphology in RBRC02421
  http://metadb.riken.jp/db/rikenbrc_mouse/Phenotype_1014224
• abnormal thymus medulla morphology in RBRC02421
  http://metadb.riken.jp/db/rikenbrc_mouse/Phenotype_1004430
• increased double-negative T cell number in RBRC02421
  http://metadb.riken.jp/db/rikenbrc_mouse/Phenotype_1004431
• thymus hypoplasia in RBRC02421
  http://metadb.riken.jp/db/rikenbrc_mouse/Phenotype_1004427
• abnormal T cell differentiation in RBRC02421
  http://metadb.riken.jp/db/rikenbrc_mouse/Phenotype_1004428
• absent thymus corticomedullary boundary in RBRC06231
  http://metadb.riken.jp/db/rikenbrc_mouse/Phenotype_1009635
• abnormal T cell morphology in RBRC02421
  http://metadb.riken.jp/db/rikenbrc_mouse/Phenotype_1004433

article

http://www.w3.org/2000/01/rdf-schema#seeAlso

• [Blank]
• [Blank]