Josiane. Ménissier de Murcia, et.al., Functional interaction between PARP-1 and PARP-2 in chromosome stability and embryonic development in mouse., The EMBO journal, 2003, 22

http://rdf.ncbi.nlm.nih.gov/pubmed/12727891

Josiane. Ménissier de Murcia, et.al., Functional interaction between PARP-1 and PARP-2 in chromosome stability and embryonic development in mouse., The EMBO journal, 2003, 22

pubmed

allele

http://purl.org/net/cito/citesAsAuthority

• Parp2<tm1Jmdm>
  http://metadb.riken.jp/db/mgi_rdf/MGI:2663016

class

http://purl.org/net/cito/citesAsAuthority

• Parp2<tm1Jmdm>
  http://metadb.riken.jp/db/mgi_rdf/MGI:2663016

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• abnormal cell cycle checkpoint function_Parp2<tm1Jmdm>/Parp2<tm1Jmdm>
  http://metadb.riken.jp/0004045I129S2SvPasC57BL6Parp2tm1JmdmParp2tm1JmdmParp2tm1Jmdm
• decreased litter size_Parp1<tm1Jmdm>/Parp1<+>,Parp2<tm1Jmdm>/Parp2<tm1Jmdm>
  http://metadb.riken.jp/0001935I129S2SvPasC57BL6Parp1tm1JmdmParp1Parp2tm1JmdmParp2tm1JmdmParp1Parp2tm1JmdmParp1tm1Jmdm
• embryonic growth arrest_Parp1<tm1Jmdm>/Parp1<tm1Jmdm>,Parp2<tm1Jmdm>/Parp2<tm1Jmdm>
  http://metadb.riken.jp/0001730I129S2SvPasC57BL6Parp1tm1JmdmParp1tm1JmdmParp2tm1JmdmParp2tm1JmdmParp2tm1JmdmParp1tm1Jmdm
• increased cellular sensitivity to gamma-irradiation_Parp2<tm1Jmdm>/Parp2<tm1Jmdm>
  http://metadb.riken.jp/0002007I129S2SvPasC57BL6Parp2tm1JmdmParp2tm1JmdmParp2tm1Jmdm
• embryonic growth arrest_Parp1<tm1Jmdm>/Parp1<+>,Parp2<tm1Jmdm>/Parp2<tm1Jmdm>
  http://metadb.riken.jp/0001730I129S2SvPasC57BL6Parp1tm1JmdmParp1Parp2tm1JmdmParp2tm1JmdmParp1Parp2tm1JmdmParp1tm1Jmdm
• embryonic lethality, complete penetrance_Parp1<tm1Jmdm>/Parp1<tm1Jmdm>,Parp2<tm1Jmdm>/Parp2<tm1Jmdm>
  http://metadb.riken.jp/0011092I129S2SvPasC57BL6Parp1tm1JmdmParp1tm1JmdmParp2tm1JmdmParp2tm1JmdmParp2tm1JmdmParp1tm1Jmdm
• abnormal DNA repair_Parp2<tm1Jmdm>/Parp2<tm1Jmdm>
  http://metadb.riken.jp/0008058I129S2SvPasC57BL6Parp2tm1JmdmParp2tm1JmdmParp2tm1Jmdm
• aneuploidy_Parp1<tm1Jmdm>/Parp1<+>,Parp2<tm1Jmdm>/Parp2<tm1Jmdm>
  http://metadb.riken.jp/0004024I129S2SvPasC57BL6Parp1tm1JmdmParp1Parp2tm1JmdmParp2tm1JmdmParp1Parp2tm1JmdmParp1tm1Jmdm
• elevated level of mitotic sister chromatid exchange_Parp2<tm1Jmdm>/Parp2<tm1Jmdm>
  http://metadb.riken.jp/0003701I129S2SvPasC57BL6Parp2tm1JmdmParp2tm1JmdmParp2tm1Jmdm
• induced chromosome breakage_Parp2<tm1Jmdm>/Parp2<tm1Jmdm>
  http://metadb.riken.jp/0004030I129S2SvPasC57BL6Parp2tm1JmdmParp2tm1JmdmParp2tm1Jmdm
• increased mortality induced by gamma-irradiation_Parp2<tm1Jmdm>/Parp2<tm1Jmdm>
  http://metadb.riken.jp/0001658I129S2SvPasC57BL6Parp2tm1JmdmParp2tm1JmdmParp2tm1Jmdm
• reduced female fertility_Parp1<tm1Jmdm>/Parp1<+>,Parp2<tm1Jmdm>/Parp2<tm1Jmdm>
  http://metadb.riken.jp/0001923I129S2SvPasC57BL6Parp1tm1JmdmParp1Parp2tm1JmdmParp2tm1JmdmParp1Parp2tm1JmdmParp1tm1Jmdm
• chromosomal instability_Parp1<tm1Jmdm>/Parp1<+>,Parp2<tm1Jmdm>/Parp2<tm1Jmdm>
  http://metadb.riken.jp/0008866I129S2SvPasC57BL6Parp1tm1JmdmParp1Parp2tm1JmdmParp2tm1JmdmParp1Parp2tm1JmdmParp1tm1Jmdm
• embryonic lethality during organogenesis, incomplete penetrance_Parp1<tm1Jmdm>/Parp1<+>,Parp2<tm1Jmdm>/Parp2<tm1Jmdm>
  http://metadb.riken.jp/0011108I129S2SvPasC57BL6Parp1tm1JmdmParp1Parp2tm1JmdmParp2tm1JmdmParp1Parp2tm1JmdmParp1tm1Jmdm