Kai. Yu, et.al., Conditional inactivation of FGF receptor 2 reveals an essential role for FGF signaling in the regulation of osteoblast function and bone growth., Development (Cambridge, England), 2003, 130

http://rdf.ncbi.nlm.nih.gov/pubmed/12756187

Kai. Yu, et.al., Conditional inactivation of FGF receptor 2 reveals an essential role for FGF signaling in the regulation of osteoblast function and bone growth., Development (Cambridge, England), 2003, 130

pubmed

allele

http://purl.org/net/cito/citesAsAuthority

• Fgfr2<tm1.1Dor>
  http://metadb.riken.jp/db/mgi_rdf/MGI:3044427
• Fgfr2<tm1Dor>
  http://metadb.riken.jp/db/mgi_rdf/MGI:3044679

class

http://purl.org/net/cito/citesAsAuthority

• Fgfr2<tm1.1Dor>
  http://metadb.riken.jp/db/mgi_rdf/MGI:3044427
• Fgfr2<tm1Dor>
  http://metadb.riken.jp/db/mgi_rdf/MGI:3044679

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• abnormal skeleton development_Fgfr2<tm1Dor>/Fgfr2<tm1.1Dor>,Twist2<tm1(cre)Dor>/Twist2<+>
  http://metadb.riken.jp/0002113I129X1SvJFgfr2tm1DorFgfr2tm11DorTwist2tm1creDorTwist2Fgfr2tm1DorTwist2tm1creDorTwist2Fgfr2tm11Dor
• short femur_Fgfr2<tm1Dor>/Fgfr2<tm1.1Dor>,Twist2<tm1(cre)Dor>/Twist2<+>
  http://metadb.riken.jp/0003109I129X1SvJFgfr2tm1DorFgfr2tm11DorTwist2tm1creDorTwist2Fgfr2tm1DorTwist2tm1creDorTwist2Fgfr2tm11Dor
• decreased osteoblast cell number_Fgfr2<tm1Dor>/Fgfr2<tm1.1Dor>,Twist2<tm1(cre)Dor>/Twist2<+>
  http://metadb.riken.jp/0004989I129X1SvJFgfr2tm1DorFgfr2tm11DorTwist2tm1creDorTwist2Fgfr2tm1DorTwist2tm1creDorTwist2Fgfr2tm11Dor
• absent vertebral spinous process_Fgfr2<tm1Dor>/Fgfr2<tm1.1Dor>,Twist2<tm1(cre)Dor>/Twist2<+>
  http://metadb.riken.jp/0004606I129X1SvJFgfr2tm1DorFgfr2tm11DorTwist2tm1creDorTwist2Fgfr2tm1DorTwist2tm1creDorTwist2Fgfr2tm11Dor
• abnormal long bone hypertrophic chondrocyte zone_Fgfr2<tm1Dor>/Fgfr2<tm1.1Dor>,Twist2<tm1(cre)Dor>/Twist2<+>
  http://metadb.riken.jp/0000165I129X1SvJFgfr2tm1DorFgfr2tm11DorTwist2tm1creDorTwist2Fgfr2tm1DorTwist2tm1creDorTwist2Fgfr2tm11Dor
• abnormal osteoclast differentiation_Fgfr2<tm1Dor>/Fgfr2<tm1.1Dor>,Twist2<tm1(cre)Dor>/Twist2<+>
  http://metadb.riken.jp/0008396I129X1SvJFgfr2tm1DorFgfr2tm11DorTwist2tm1creDorTwist2Fgfr2tm1DorTwist2tm1creDorTwist2Fgfr2tm11Dor
• abnormal thoracic vertebrae morphology_Fgfr2<tm1Dor>/Fgfr2<tm1.1Dor>,Twist2<tm1(cre)Dor>/Twist2<+>
  http://metadb.riken.jp/0003047I129X1SvJFgfr2tm1DorFgfr2tm11DorTwist2tm1creDorTwist2Fgfr2tm1DorTwist2tm1creDorTwist2Fgfr2tm11Dor
• decreased cell proliferation_Fgfr2<tm1Dor>/Fgfr2<tm1.1Dor>,Twist2<tm1(cre)Dor>/Twist2<+>
  http://metadb.riken.jp/0000352I129X1SvJFgfr2tm1DorFgfr2tm11DorTwist2tm1creDorTwist2Fgfr2tm1DorTwist2tm1creDorTwist2Fgfr2tm11Dor
• no abnormal phenotype detected_Twist2<tm1(cre)Dor>/Twist2<+>
  http://metadb.riken.jp/0002169I129X1SvJTwist2tm1creDorTwist2Twist2tm1creDorTwist2
• abnormal vertebrae morphology_Fgfr2<tm1Dor>/Fgfr2<tm1.1Dor>,Twist2<tm1(cre)Dor>/Twist2<+>
  http://metadb.riken.jp/0000137I129X1SvJFgfr2tm1DorFgfr2tm11DorTwist2tm1creDorTwist2Fgfr2tm1DorTwist2tm1creDorTwist2Fgfr2tm11Dor
• abnormal cervical vertebrae morphology_Fgfr2<tm1Dor>/Fgfr2<tm1.1Dor>,Twist2<tm1(cre)Dor>/Twist2<+>
  http://metadb.riken.jp/0003048I129X1SvJFgfr2tm1DorFgfr2tm11DorTwist2tm1creDorTwist2Fgfr2tm1DorTwist2tm1creDorTwist2Fgfr2tm11Dor
• embryonic lethality during organogenesis, complete penetrance_Fgfr2<tm1.1Dor>/Fgfr2<tm1.1Dor>
  http://metadb.riken.jp/0011098I129X1SvJFgfr2tm11DorFgfr2tm11DorFgfr2tm11Dor
• absent limb buds_Fgfr2<tm1.1Dor>/Fgfr2<tm1.1Dor>
  http://metadb.riken.jp/0004573I129X1SvJFgfr2tm11DorFgfr2tm11DorFgfr2tm11Dor
• abnormal joint morphology_Fgfr2<tm1Dor>/Fgfr2<tm1.1Dor>,Twist2<tm1(cre)Dor>/Twist2<+>
  http://metadb.riken.jp/0002932I129X1SvJFgfr2tm1DorFgfr2tm11DorTwist2tm1creDorTwist2Fgfr2tm1DorTwist2tm1creDorTwist2Fgfr2tm11Dor
• abnormal osteoblast physiology_Fgfr2<tm1Dor>/Fgfr2<tm1.1Dor>,Twist2<tm1(cre)Dor>/Twist2<+>
  http://metadb.riken.jp/0005006I129X1SvJFgfr2tm1DorFgfr2tm11DorTwist2tm1creDorTwist2Fgfr2tm1DorTwist2tm1creDorTwist2Fgfr2tm11Dor
• abnormal appendicular skeleton morphology_Fgfr2<tm1Dor>/Fgfr2<tm1.1Dor>,Twist2<tm1(cre)Dor>/Twist2<+>
  http://metadb.riken.jp/0009250I129X1SvJFgfr2tm1DorFgfr2tm11DorTwist2tm1creDorTwist2Fgfr2tm1DorTwist2tm1creDorTwist2Fgfr2tm11Dor
• abnormal axial skeleton morphology_Fgfr2<tm1Dor>/Fgfr2<tm1.1Dor>,Twist2<tm1(cre)Dor>/Twist2<+>
  http://metadb.riken.jp/0002114I129X1SvJFgfr2tm1DorFgfr2tm11DorTwist2tm1creDorTwist2Fgfr2tm1DorTwist2tm1creDorTwist2Fgfr2tm11Dor
• decreased bone mineral density_Fgfr2<tm1Dor>/Fgfr2<tm1.1Dor>,Twist2<tm1(cre)Dor>/Twist2<+>
  http://metadb.riken.jp/0000063I129X1SvJFgfr2tm1DorFgfr2tm11DorTwist2tm1creDorTwist2Fgfr2tm1DorTwist2tm1creDorTwist2Fgfr2tm11Dor
• domed cranium_Fgfr2<tm1Dor>/Fgfr2<tm1.1Dor>,Twist2<tm1(cre)Dor>/Twist2<+>
  http://metadb.riken.jp/0000440I129X1SvJFgfr2tm1DorFgfr2tm11DorTwist2tm1creDorTwist2Fgfr2tm1DorTwist2tm1creDorTwist2Fgfr2tm11Dor
• abnormal long bone metaphysis morphology_Fgfr2<tm1Dor>/Fgfr2<tm1.1Dor>,Twist2<tm1(cre)Dor>/Twist2<+>
  http://metadb.riken.jp/0000133I129X1SvJFgfr2tm1DorFgfr2tm11DorTwist2tm1creDorTwist2Fgfr2tm1DorTwist2tm1creDorTwist2Fgfr2tm11Dor
• abnormal vertebrae development_Fgfr2<tm1Dor>/Fgfr2<tm1.1Dor>,Twist2<tm1(cre)Dor>/Twist2<+>
  http://metadb.riken.jp/0005225I129X1SvJFgfr2tm1DorFgfr2tm11DorTwist2tm1creDorTwist2Fgfr2tm1DorTwist2tm1creDorTwist2Fgfr2tm11Dor
• postnatal growth retardation_Fgfr2<tm1Dor>/Fgfr2<tm1.1Dor>,Twist2<tm1(cre)Dor>/Twist2<+>
  http://metadb.riken.jp/0001732I129X1SvJFgfr2tm1DorFgfr2tm11DorTwist2tm1creDorTwist2Fgfr2tm1DorTwist2tm1creDorTwist2Fgfr2tm11Dor
• abnormal placenta development_Fgfr2<tm1.1Dor>/Fgfr2<tm1.1Dor>
  http://metadb.riken.jp/0001712I129X1SvJFgfr2tm11DorFgfr2tm11DorFgfr2tm11Dor
• disproportionate dwarf_Fgfr2<tm1Dor>/Fgfr2<tm1.1Dor>,Twist2<tm1(cre)Dor>/Twist2<+>
  http://metadb.riken.jp/0002427I129X1SvJFgfr2tm1DorFgfr2tm11DorTwist2tm1creDorTwist2Fgfr2tm1DorTwist2tm1creDorTwist2Fgfr2tm11Dor