Silvia. Marino, et.al., Rb and p107 are required for normal cerebellar development and granule cell survival but not for Purkinje cell persistence., Development (Cambridge, England), 2003, 130

http://rdf.ncbi.nlm.nih.gov/pubmed/12810584

Silvia. Marino, et.al., Rb and p107 are required for normal cerebellar development and granule cell survival but not for Purkinje cell persistence., Development (Cambridge, England), 2003, 130

pubmed

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• abnormal cerebellum vermis morphology_Rb1<tm2Brn>/Rb1<tm2Brn>,Rbl1<tm1Htr>/Rbl1<tm1Htr>,Tg(En2-cre)22Alj/0
  http://metadb.riken.jp/0000864I129P2OlaHsdCD1Rb1tm2BrnRb1tm2BrnRbl1tm1HtrRbl1tm1HtrTgEn2cre22Alj0Rb1tm2BrnRbl1tm1HtrTgEn2cre22Alj
• abnormal neuronal precursor proliferation_Rb1<tm2Brn>/Rb1<tm2Brn>,Rbl1<tm1Htr>/Rbl1<tm1Htr>,Tg(En2-cre)22Alj/0
  http://metadb.riken.jp/0004948I129P2OlaHsdCD1Rb1tm2BrnRb1tm2BrnRbl1tm1HtrRbl1tm1HtrTgEn2cre22Alj0Rb1tm2BrnRbl1tm1HtrTgEn2cre22Alj
• abnormal Purkinje cell morphology_Rb1<tm2Brn>/Rb1<tm2Brn>,Rbl1<tm1Htr>/Rbl1<tm1Htr>,Tg(Pcp2-cre)756Mro/0
  http://metadb.riken.jp/0000877I129P2OlaHsdFVBRb1tm2BrnRb1tm2BrnRbl1tm1HtrRbl1tm1HtrTgPcp2cre756Mro0Rb1tm2BrnTgPcp2cre756MroRbl1tm1Htr
• ataxia_Rb1<tm2Brn>/Rb1<tm2Brn>,Rbl1<tm1Htr>/Rbl1<tm1Htr>,Tg(En2-cre)22Alj/0
  http://metadb.riken.jp/0001393I129P2OlaHsdCD1Rb1tm2BrnRb1tm2BrnRbl1tm1HtrRbl1tm1HtrTgEn2cre22Alj0Rb1tm2BrnRbl1tm1HtrTgEn2cre22Alj
• abnormal brain interneuron morphology_Rb1<tm2Brn>/Rb1<tm2Brn>,Tg(En2-cre)22Alj/0
  http://metadb.riken.jp/0004101I129P2OlaHsdCD1Rb1tm2BrnRb1tm2BrnTgEn2cre22Alj0Rb1tm2BrnTgEn2cre22Alj
• abnormal Purkinje cell morphology_Rb1<tm2Brn>/Rb1<tm2Brn>,Rbl1<tm1Htr>/Rbl1<tm1Htr>,Tg(En2-cre)22Alj/0
  http://metadb.riken.jp/0000877I129P2OlaHsdCD1Rb1tm2BrnRb1tm2BrnRbl1tm1HtrRbl1tm1HtrTgEn2cre22Alj0Rb1tm2BrnRbl1tm1HtrTgEn2cre22Alj
• astrocytosis_Rb1<tm2Brn>/Rb1<tm2Brn>,Tg(En2-cre)22Alj/0
  http://metadb.riken.jp/0003354I129P2OlaHsdCD1Rb1tm2BrnRb1tm2BrnTgEn2cre22Alj0Rb1tm2BrnTgEn2cre22Alj
• ataxia_Rb1<tm2Brn>/Rb1<tm2Brn>,Rbl1<tm1Htr>/Rbl1<+>,Tg(En2-cre)22Alj/0
  http://metadb.riken.jp/0001393I129P2OlaHsdCD1Rb1tm2BrnRb1tm2BrnRbl1tm1HtrRbl1TgEn2cre22Alj0Rb1tm2BrnRbl1TgEn2cre22AljRbl1tm1Htr
• thin external granule cell layer_Rb1<tm2Brn>/Rb1<tm2Brn>,Tg(En2-cre)22Alj/0
  http://metadb.riken.jp/0000873I129P2OlaHsdCD1Rb1tm2BrnRb1tm2BrnTgEn2cre22Alj0Rb1tm2BrnTgEn2cre22Alj
• abnormal cerebellar granule layer morphology_Rb1<tm2Brn>/Rb1<tm2Brn>,Tg(En2-cre)22Alj/0
  http://metadb.riken.jp/0000886I129P2OlaHsdCD1Rb1tm2BrnRb1tm2BrnTgEn2cre22Alj0Rb1tm2BrnTgEn2cre22Alj
• abnormal cerebellum vermis morphology_Rb1<tm2Brn>/Rb1<tm2Brn>,Tg(Pcp2-cre)756Mro/0
  http://metadb.riken.jp/0000864I129P2OlaHsdFVBRb1tm2BrnRb1tm2BrnTgPcp2cre756Mro0Rb1tm2BrnTgPcp2cre756Mro
• abnormal neuronal precursor proliferation_Rb1<tm2Brn>/Rb1<tm2Brn>,Tg(En2-cre)22Alj/0
  http://metadb.riken.jp/0004948I129P2OlaHsdCD1Rb1tm2BrnRb1tm2BrnTgEn2cre22Alj0Rb1tm2BrnTgEn2cre22Alj
• abnormal Purkinje cell morphology_Rb1<tm2Brn>/Rb1<tm2Brn>,Tg(En2-cre)22Alj/0
  http://metadb.riken.jp/0000877I129P2OlaHsdCD1Rb1tm2BrnRb1tm2BrnTgEn2cre22Alj0Rb1tm2BrnTgEn2cre22Alj
• abnormal cerebellum external granule cell layer morphology_Rb1<tm2Brn>/Rb1<tm2Brn>,Tg(En2-cre)22Alj/0
  http://metadb.riken.jp/0000872I129P2OlaHsdCD1Rb1tm2BrnRb1tm2BrnTgEn2cre22Alj0Rb1tm2BrnTgEn2cre22Alj
• thin cerebellar molecular layer_Rb1<tm2Brn>/Rb1<tm2Brn>,Rbl1<tm1Htr>/Rbl1<tm1Htr>,Tg(En2-cre)22Alj/0
  http://metadb.riken.jp/0000890I129P2OlaHsdCD1Rb1tm2BrnRb1tm2BrnRbl1tm1HtrRbl1tm1HtrTgEn2cre22Alj0Rb1tm2BrnRbl1tm1HtrTgEn2cre22Alj
• increased neuron apoptosis_Rb1<tm2Brn>/Rb1<tm2Brn>,Rbl1<tm1Htr>/Rbl1<+>,Tg(En2-cre)22Alj/0
  http://metadb.riken.jp/0003203I129P2OlaHsdCD1Rb1tm2BrnRb1tm2BrnRbl1tm1HtrRbl1TgEn2cre22Alj0Rb1tm2BrnRbl1TgEn2cre22AljRbl1tm1Htr
• increased neuron apoptosis_Rb1<tm2Brn>/Rb1<tm2Brn>,Tg(En2-cre)22Alj/0
  http://metadb.riken.jp/0003203I129P2OlaHsdCD1Rb1tm2BrnRb1tm2BrnTgEn2cre22Alj0Rb1tm2BrnTgEn2cre22Alj
• abnormal neuronal precursor proliferation_Rb1<tm2Brn>/Rb1<tm2Brn>,Rbl1<tm1Htr>/Rbl1<+>,Tg(En2-cre)22Alj/0
  http://metadb.riken.jp/0004948I129P2OlaHsdCD1Rb1tm2BrnRb1tm2BrnRbl1tm1HtrRbl1TgEn2cre22Alj0Rb1tm2BrnRbl1TgEn2cre22AljRbl1tm1Htr
• abnormal cerebellum vermis morphology_Rb1<tm2Brn>/Rb1<tm2Brn>,Rbl1<tm1Htr>/Rbl1<+>,Tg(En2-cre)22Alj/0
  http://metadb.riken.jp/0000864I129P2OlaHsdCD1Rb1tm2BrnRb1tm2BrnRbl1tm1HtrRbl1TgEn2cre22Alj0Rb1tm2BrnRbl1TgEn2cre22AljRbl1tm1Htr
• cerebellum hypoplasia_Rb1<tm2Brn>/Rb1<tm2Brn>,Rbl1<tm1Htr>/Rbl1<+>,Tg(En2-cre)22Alj/0
  http://metadb.riken.jp/0000851I129P2OlaHsdCD1Rb1tm2BrnRb1tm2BrnRbl1tm1HtrRbl1TgEn2cre22Alj0Rb1tm2BrnRbl1TgEn2cre22AljRbl1tm1Htr
• abnormal cerebellar granule cell morphology_Rb1<tm2Brn>/Rb1<tm2Brn>,Tg(En2-cre)22Alj/0
  http://metadb.riken.jp/0004098I129P2OlaHsdCD1Rb1tm2BrnRb1tm2BrnTgEn2cre22Alj0Rb1tm2BrnTgEn2cre22Alj
• abnormal cerebellar cortex morphology_Rb1<tm2Brn>/Rb1<tm2Brn>,Rbl1<tm1Htr>/Rbl1<tm1Htr>,Tg(En2-cre)22Alj/0
  http://metadb.riken.jp/0004097I129P2OlaHsdCD1Rb1tm2BrnRb1tm2BrnRbl1tm1HtrRbl1tm1HtrTgEn2cre22Alj0Rb1tm2BrnRbl1tm1HtrTgEn2cre22Alj
• abnormal cerebellar cortex morphology_Rb1<tm2Brn>/Rb1<tm2Brn>,Tg(En2-cre)22Alj/0
  http://metadb.riken.jp/0004097I129P2OlaHsdCD1Rb1tm2BrnRb1tm2BrnTgEn2cre22Alj0Rb1tm2BrnTgEn2cre22Alj