Kathleen H. Burns, et.al., Sexually dimorphic roles of steroid hormone receptor signaling in gonadal tumorigenesis., Molecular endocrinology (Baltimore, Md.), 2003, 17

http://rdf.ncbi.nlm.nih.gov/pubmed/12855748

Kathleen H. Burns, et.al., Sexually dimorphic roles of steroid hormone receptor signaling in gonadal tumorigenesis., Molecular endocrinology (Baltimore, Md.), 2003, 17

pubmed

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• cachexia_Esr1<tm1Ksk>/Esr1<tm1Ksk>,Esr2<tm1Unc>/Esr2<tm1Unc>,Inha<tm1Bay>/Inha<tm1Bay>
  http://metadb.riken.jp/0005150I129P2OlaHsd129S6SvEvTac129S7SvEvBrdEsr1tm1KskEsr1tm1KskEsr2tm1UncEsr2tm1UncInhatm1BayInhatm1BayInhatm1BayEsr2tm1UncEsr1tm1Ksk
• dilated seminiferous tubules_Esr1<tm1Ksk>/Esr1<tm1Ksk>,Esr2<tm1Unc>/Esr2<tm1Unc>,Inha<tm1Bay>/Inha<tm1Bay>
  http://metadb.riken.jp/0009257I129P2OlaHsd129S6SvEvTac129S7SvEvBrdEsr1tm1KskEsr1tm1KskEsr2tm1UncEsr2tm1UncInhatm1BayInhatm1BayInhatm1BayEsr2tm1UncEsr1tm1Ksk
• increased circulating estradiol level_Esr1<tm1Ksk>/Esr1<tm1Ksk>
  http://metadb.riken.jp/0005182I129P2OlaHsd129S6SvEvTacEsr1tm1KskEsr1tm1KskEsr1tm1Ksk
• abnormal ovary morphology_Esr1<tm1Ksk>/Esr1<tm1Ksk>,Esr2<tm1Unc>/Esr2<tm1Unc>,Inha<tm1Bay>/Inha<tm1Bay>
  http://metadb.riken.jp/0001126I129P2OlaHsd129S6SvEvTac129S7SvEvBrdEsr1tm1KskEsr1tm1KskEsr2tm1UncEsr2tm1UncInhatm1BayInhatm1BayInhatm1BayEsr2tm1UncEsr1tm1Ksk
• abnormal liver morphology_Esr2<tm1Unc>/Esr2<tm1Unc>,Inha<tm1Bay>/Inha<tm1Bay>
  http://metadb.riken.jp/0000598I129P2OlaHsd129S6SvEvTac129S7SvEvBrdEsr2tm1UncEsr2tm1UncInhatm1BayInhatm1BayEsr2tm1UncInhatm1Bay
• dilated seminiferous tubules_Esr1<tm1Ksk>/Esr1<tm1Ksk>
  http://metadb.riken.jp/0009257I129P2OlaHsd129S6SvEvTacEsr1tm1KskEsr1tm1KskEsr1tm1Ksk
• abnormal stomach morphology_Esr2<tm1Unc>/Esr2<tm1Unc>,Inha<tm1Bay>/Inha<tm1Bay>
  http://metadb.riken.jp/0000470I129P2OlaHsd129S6SvEvTac129S7SvEvBrdEsr2tm1UncEsr2tm1UncInhatm1BayInhatm1BayEsr2tm1UncInhatm1Bay
• kyphoscoliosis_Esr1<tm1Ksk>/Esr1<tm1Ksk>,Inha<tm1Bay>/Inha<tm1Bay>
  http://metadb.riken.jp/0000069I129P2OlaHsd129S6SvEvTac129S7SvEvBrdEsr1tm1KskEsr1tm1KskInhatm1BayInhatm1BayEsr1tm1KskInhatm1Bay
• increased testis tumor incidence_Inha<tm1Bay>/Inha<tm1Bay>
  http://metadb.riken.jp/0006262I129S6SvEvTac129S7SvEvBrdInhatm1BayInhatm1BayInhatm1Bay
• cachexia_Esr2<tm1Unc>/Esr2<tm1Unc>,Inha<tm1Bay>/Inha<tm1Bay>
  http://metadb.riken.jp/0005150I129P2OlaHsd129S6SvEvTac129S7SvEvBrdEsr2tm1UncEsr2tm1UncInhatm1BayInhatm1BayEsr2tm1UncInhatm1Bay
• increased ovary tumor incidence_Esr2<tm1Unc>/Esr2<tm1Unc>,Inha<tm1Bay>/Inha<tm1Bay>
  http://metadb.riken.jp/0008000I129P2OlaHsd129S6SvEvTac129S7SvEvBrdEsr2tm1UncEsr2tm1UncInhatm1BayInhatm1BayEsr2tm1UncInhatm1Bay
• increased body weight_Esr1<tm1Ksk>/Esr1<tm1Ksk>,Esr2<tm1Unc>/Esr2<tm1Unc>,Inha<tm1Bay>/Inha<tm1Bay>
  http://metadb.riken.jp/0001260I129P2OlaHsd129S6SvEvTac129S7SvEvBrdEsr1tm1KskEsr1tm1KskEsr2tm1UncEsr2tm1UncInhatm1BayInhatm1BayInhatm1BayEsr2tm1UncEsr1tm1Ksk
• abnormal ovary morphology_Esr1<tm1Ksk>/Esr1<tm1Ksk>,Esr2<tm1Unc>/Esr2<tm1Unc>,Inha<tm1Bay>/Inha<+>
  http://metadb.riken.jp/0001126I129P2OlaHsd129S6SvEvTac129S7SvEvBrdEsr1tm1KskEsr1tm1KskEsr2tm1UncEsr2tm1UncInhatm1BayInhaEsr1tm1KskInhaInhatm1BayEsr2tm1Unc
• abnormal stomach glandular epithelium morphology_Esr1<tm1Ksk>/Esr1<tm1Ksk>,Inha<tm1Bay>/Inha<tm1Bay>
  http://metadb.riken.jp/0000473I129P2OlaHsd129S6SvEvTac129S7SvEvBrdEsr1tm1KskEsr1tm1KskInhatm1BayInhatm1BayEsr1tm1KskInhatm1Bay
• decreased circulating follicle stimulating hormone level_Inha<tm1Bay>/Inha<tm1Bay>
  http://metadb.riken.jp/0002790I129S6SvEvTac129S7SvEvBrdInhatm1BayInhatm1BayInhatm1Bay
• extended life span_Inha<tm1Bay>/Inha<tm1Bay>
  http://metadb.riken.jp/0001661I129S6SvEvTac129S7SvEvBrdInhatm1BayInhatm1BayInhatm1Bay
• decreased body weight_Esr1<tm1Ksk>/Esr1<tm1Ksk>,Inha<tm1Bay>/Inha<tm1Bay>
  http://metadb.riken.jp/0001262I129P2OlaHsd129S6SvEvTac129S7SvEvBrdEsr1tm1KskEsr1tm1KskInhatm1BayInhatm1BayEsr1tm1KskInhatm1Bay
• premature death_Inha<tm1Bay>/Inha<tm1Bay>
  http://metadb.riken.jp/0002083I129S6SvEvTac129S7SvEvBrdInhatm1BayInhatm1BayInhatm1Bay
• increased ovary tumor incidence_Esr1<tm1Ksk>/Esr1<tm1Ksk>,Inha<tm1Bay>/Inha<tm1Bay>
  http://metadb.riken.jp/0008000I129P2OlaHsd129S6SvEvTac129S7SvEvBrdEsr1tm1KskEsr1tm1KskInhatm1BayInhatm1BayEsr1tm1KskInhatm1Bay
• premature death_Esr1<tm1Ksk>/Esr1<tm1Ksk>,Esr2<tm1Unc>/Esr2<tm1Unc>,Inha<tm1Bay>/Inha<tm1Bay>
  http://metadb.riken.jp/0002083I129P2OlaHsd129S6SvEvTac129S7SvEvBrdEsr1tm1KskEsr1tm1KskEsr2tm1UncEsr2tm1UncInhatm1BayInhatm1BayInhatm1BayEsr2tm1UncEsr1tm1Ksk
• increased ovary tumor incidence_Inha<tm1Bay>/Inha<tm1Bay>
  http://metadb.riken.jp/0008000I129S6SvEvTac129S7SvEvBrdInhatm1BayInhatm1BayInhatm1Bay
• cachexia_Inha<tm1Bay>/Inha<tm1Bay>
  http://metadb.riken.jp/0005150I129S6SvEvTac129S7SvEvBrdInhatm1BayInhatm1BayInhatm1Bay
• increased ovary tumor incidence_Esr1<tm1Ksk>/Esr1<tm1Ksk>,Esr2<tm1Unc>/Esr2<tm1Unc>,Inha<tm1Bay>/Inha<+>
  http://metadb.riken.jp/0008000I129P2OlaHsd129S6SvEvTac129S7SvEvBrdEsr1tm1KskEsr1tm1KskEsr2tm1UncEsr2tm1UncInhatm1BayInhaEsr1tm1KskInhaInhatm1BayEsr2tm1Unc
• abnormal hepatocyte morphology_Esr1<tm1Ksk>/Esr1<tm1Ksk>,Inha<tm1Bay>/Inha<tm1Bay>
  http://metadb.riken.jp/0000607I129P2OlaHsd129S6SvEvTac129S7SvEvBrdEsr1tm1KskEsr1tm1KskInhatm1BayInhatm1BayEsr1tm1KskInhatm1Bay
• hepatic necrosis_Esr1<tm1Ksk>/Esr1<tm1Ksk>,Inha<tm1Bay>/Inha<tm1Bay>
  http://metadb.riken.jp/0001654I129P2OlaHsd129S6SvEvTac129S7SvEvBrdEsr1tm1KskEsr1tm1KskInhatm1BayInhatm1BayEsr1tm1KskInhatm1Bay
• increased circulating estradiol level_Inha<tm1Bay>/Inha<tm1Bay>
  http://metadb.riken.jp/0005182I129S6SvEvTac129S7SvEvBrdInhatm1BayInhatm1BayInhatm1Bay
• decreased male germ cell number_Esr1<tm1Ksk>/Esr1<tm1Ksk>,Esr2<tm1Unc>/Esr2<tm1Unc>,Inha<tm1Bay>/Inha<tm1Bay>
  http://metadb.riken.jp/0004901I129P2OlaHsd129S6SvEvTac129S7SvEvBrdEsr1tm1KskEsr1tm1KskEsr2tm1UncEsr2tm1UncInhatm1BayInhatm1BayInhatm1BayEsr2tm1UncEsr1tm1Ksk
• increased ovary tumor incidence_Esr1<tm1Ksk>/Esr1<tm1Ksk>,Esr2<tm1Unc>/Esr2<tm1Unc>,Inha<tm1Bay>/Inha<tm1Bay>
  http://metadb.riken.jp/0008000I129P2OlaHsd129S6SvEvTac129S7SvEvBrdEsr1tm1KskEsr1tm1KskEsr2tm1UncEsr2tm1UncInhatm1BayInhatm1BayInhatm1BayEsr2tm1UncEsr1tm1Ksk
• premature death_Esr2<tm1Unc>/Esr2<tm1Unc>,Inha<tm1Bay>/Inha<tm1Bay>
  http://metadb.riken.jp/0002083I129P2OlaHsd129S6SvEvTac129S7SvEvBrdEsr2tm1UncEsr2tm1UncInhatm1BayInhatm1BayEsr2tm1UncInhatm1Bay
• liver inflammation_Esr1<tm1Ksk>/Esr1<tm1Ksk>,Inha<tm1Bay>/Inha<tm1Bay>
  http://metadb.riken.jp/0001860I129P2OlaHsd129S6SvEvTac129S7SvEvBrdEsr1tm1KskEsr1tm1KskInhatm1BayInhatm1BayEsr1tm1KskInhatm1Bay
• decreased circulating follicle stimulating hormone level_Esr1<tm1Ksk>/Esr1<tm1Ksk>,Inha<tm1Bay>/Inha<tm1Bay>
  http://metadb.riken.jp/0002790I129P2OlaHsd129S6SvEvTac129S7SvEvBrdEsr1tm1KskEsr1tm1KskInhatm1BayInhatm1BayEsr1tm1KskInhatm1Bay
• increased testis tumor incidence_Esr2<tm1Unc>/Esr2<tm1Unc>,Inha<tm1Bay>/Inha<tm1Bay>
  http://metadb.riken.jp/0006262I129P2OlaHsd129S6SvEvTac129S7SvEvBrdEsr2tm1UncEsr2tm1UncInhatm1BayInhatm1BayEsr2tm1UncInhatm1Bay
• premature death_Esr1<tm1Ksk>/Esr1<tm1Ksk>,Inha<tm1Bay>/Inha<tm1Bay>
  http://metadb.riken.jp/0002083I129P2OlaHsd129S6SvEvTac129S7SvEvBrdEsr1tm1KskEsr1tm1KskInhatm1BayInhatm1BayEsr1tm1KskInhatm1Bay
• abnormal seminiferous tubule morphology_Esr1<tm1Ksk>/Esr1<tm1Ksk>,Esr2<tm1Unc>/Esr2<tm1Unc>,Inha<tm1Bay>/Inha<tm1Bay>
  http://metadb.riken.jp/0002216I129P2OlaHsd129S6SvEvTac129S7SvEvBrdEsr1tm1KskEsr1tm1KskEsr2tm1UncEsr2tm1UncInhatm1BayInhatm1BayInhatm1BayEsr2tm1UncEsr1tm1Ksk
• cachexia_Esr1<tm1Ksk>/Esr1<tm1Ksk>,Inha<tm1Bay>/Inha<tm1Bay>
  http://metadb.riken.jp/0005150I129P2OlaHsd129S6SvEvTac129S7SvEvBrdEsr1tm1KskEsr1tm1KskInhatm1BayInhatm1BayEsr1tm1KskInhatm1Bay
• increased testis tumor incidence_Esr1<tm1Ksk>/Esr1<tm1Ksk>,Inha<tm1Bay>/Inha<tm1Bay>
  http://metadb.riken.jp/0006262I129P2OlaHsd129S6SvEvTac129S7SvEvBrdEsr1tm1KskEsr1tm1KskInhatm1BayInhatm1BayEsr1tm1KskInhatm1Bay
• decreased circulating follicle stimulating hormone level_Esr1<tm1Ksk>/Esr1<tm1Ksk>,Esr2<tm1Unc>/Esr2<tm1Unc>,Inha<tm1Bay>/Inha<tm1Bay>
  http://metadb.riken.jp/0002790I129P2OlaHsd129S6SvEvTac129S7SvEvBrdEsr1tm1KskEsr1tm1KskEsr2tm1UncEsr2tm1UncInhatm1BayInhatm1BayInhatm1BayEsr2tm1UncEsr1tm1Ksk
• decreased circulating luteinizing hormone level_Esr1<tm1Ksk>/Esr1<tm1Ksk>,Inha<tm1Bay>/Inha<tm1Bay>
  http://metadb.riken.jp/0002773I129P2OlaHsd129S6SvEvTac129S7SvEvBrdEsr1tm1KskEsr1tm1KskInhatm1BayInhatm1BayEsr1tm1KskInhatm1Bay
• increased circulating estradiol level_Esr1<tm1Ksk>/Esr1<tm1Ksk>,Inha<tm1Bay>/Inha<tm1Bay>
  http://metadb.riken.jp/0005182I129P2OlaHsd129S6SvEvTac129S7SvEvBrdEsr1tm1KskEsr1tm1KskInhatm1BayInhatm1BayEsr1tm1KskInhatm1Bay
• decreased body weight_Esr1<tm1Ksk>/Esr1<tm1Ksk>,Esr2<tm1Unc>/Esr2<tm1Unc>,Inha<tm1Bay>/Inha<tm1Bay>
  http://metadb.riken.jp/0001262I129P2OlaHsd129S6SvEvTac129S7SvEvBrdEsr1tm1KskEsr1tm1KskEsr2tm1UncEsr2tm1UncInhatm1BayInhatm1BayInhatm1BayEsr2tm1UncEsr1tm1Ksk
• abnormal stomach mucosa morphology_Esr1<tm1Ksk>/Esr1<tm1Ksk>,Inha<tm1Bay>/Inha<tm1Bay>
  http://metadb.riken.jp/0010792I129P2OlaHsd129S6SvEvTac129S7SvEvBrdEsr1tm1KskEsr1tm1KskInhatm1BayInhatm1BayEsr1tm1KskInhatm1Bay
• increased testis tumor incidence_Esr1<tm1Ksk>/Esr1<tm1Ksk>,Esr2<tm1Unc>/Esr2<tm1Unc>,Inha<tm1Bay>/Inha<tm1Bay>
  http://metadb.riken.jp/0006262I129P2OlaHsd129S6SvEvTac129S7SvEvBrdEsr1tm1KskEsr1tm1KskEsr2tm1UncEsr2tm1UncInhatm1BayInhatm1BayInhatm1BayEsr2tm1UncEsr1tm1Ksk