Peter. Papathanasiou, et.al., Widespread failure of hematolymphoid differentiation caused by a recessive niche-filling allele of the Ikaros transcription factor., Immunity, 2003, 19

http://rdf.ncbi.nlm.nih.gov/pubmed/12871645

Peter. Papathanasiou, et.al., Widespread failure of hematolymphoid differentiation caused by a recessive niche-filling allele of the Ikaros transcription factor., Immunity, 2003, 19

pubmed

allele

http://purl.org/net/cito/citesAsAuthority

• Ikzf1<plstc>
  http://metadb.riken.jp/db/mgi_rdf/MGI:2669987

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• decreased pre-B cell number_Ikzf1<plstc>/Ikzf1<+>
  http://metadb.riken.jp/0008209C57BL6JSfdAnuIkzf1plstcIkzf1plstcIkzf1Ikzf1plstcIkzf1
• decreased mature B cell number_Ikzf1<plstc>/Ikzf1<+>
  http://metadb.riken.jp/0008211C57BL6JSfdAnuIkzf1plstcIkzf1plstcIkzf1Ikzf1plstcIkzf1
• thymus hypoplasia_Ikzf1<plstc>/Ikzf1<plstc>
  http://metadb.riken.jp/0001823C57BL6JSfdAnuIkzf1plstcIkzf1plstcIkzf1plstcIkzf1plstc
• increased pro-B cell number_Ikzf1<plstc>/Ikzf1<+>
  http://metadb.riken.jp/0008186C57BL6JSfdAnuIkzf1plstcIkzf1plstcIkzf1Ikzf1plstcIkzf1
• decreased hemoglobin content_Ikzf1<plstc>/Ikzf1<plstc>
  http://metadb.riken.jp/0002874C57BL6JSfdAnuIkzf1plstcIkzf1plstcIkzf1plstcIkzf1plstc
• abnormal macrophage differentiation_Ikzf1<plstc>/Ikzf1<plstc>
  http://metadb.riken.jp/0008113C57BL6JSfdAnuIkzf1plstcIkzf1plstcIkzf1plstcIkzf1plstc
• abnormal erythropoiesis_Ikzf1<plstc>/Ikzf1<tm2Kge>
  http://metadb.riken.jp/0000245I129S4SvJaeC57BL6C57BL6JSfdAnuIkzf1plstcIkzf1tm2KgeIkzf1plstcIkzf1tm2Kge
• increased leukemia incidence_Ikzf1<plstc>/Ikzf1<+>
  http://metadb.riken.jp/0002026C57BL6JSfdAnuIkzf1plstcIkzf1plstcIkzf1Ikzf1plstcIkzf1
• increased macrophage cell number_Ikzf1<plstc>/Ikzf1<plstc>
  http://metadb.riken.jp/0005425C57BL6JSfdAnuIkzf1plstcIkzf1plstcIkzf1plstcIkzf1plstc
• decreased granulocyte number_Ikzf1<plstc>/Ikzf1<plstc>
  http://metadb.riken.jp/0000334C57BL6JSfdAnuIkzf1plstcIkzf1plstcIkzf1plstcIkzf1plstc
• arrested B cell differentiation_Ikzf1<plstc>/Ikzf1<plstc>
  http://metadb.riken.jp/0001802C57BL6JSfdAnuIkzf1plstcIkzf1plstcIkzf1plstcIkzf1plstc
• liver hypoplasia_Ikzf1<plstc>/Ikzf1<plstc>
  http://metadb.riken.jp/0000600C57BL6JSfdAnuIkzf1plstcIkzf1plstcIkzf1plstcIkzf1plstc
• premature death_Ikzf1<plstc>/Ikzf1<+>
  http://metadb.riken.jp/0002083C57BL6JSfdAnuIkzf1plstcIkzf1plstcIkzf1Ikzf1plstcIkzf1
• reticulocytopenia_Ikzf1<plstc>/Ikzf1<plstc>
  http://metadb.riken.jp/0008941C57BL6JSfdAnuIkzf1plstcIkzf1plstcIkzf1plstcIkzf1plstc
• absent T cells_Ikzf1<plstc>/Ikzf1<plstc>
  http://metadb.riken.jp/0008070C57BL6JSfdAnuIkzf1plstcIkzf1plstcIkzf1plstcIkzf1plstc
• pallor_Ikzf1<plstc>/Ikzf1<plstc>
  http://metadb.riken.jp/0003717C57BL6JSfdAnuIkzf1plstcIkzf1plstcIkzf1plstcIkzf1plstc
• abnormal lymphopoiesis_Ikzf1<plstc>/Ikzf1<plstc>
  http://metadb.riken.jp/0002401C57BL6JSfdAnuIkzf1plstcIkzf1plstcIkzf1plstcIkzf1plstc
• abnormal B cell differentiation_Ikzf1<plstc>/Ikzf1<+>
  http://metadb.riken.jp/0002144C57BL6JSfdAnuIkzf1plstcIkzf1plstcIkzf1Ikzf1plstcIkzf1
• decreased thymocyte number_Ikzf1<plstc>/Ikzf1<+>
  http://metadb.riken.jp/0000715C57BL6JSfdAnuIkzf1plstcIkzf1plstcIkzf1Ikzf1plstcIkzf1
• abnormal granulocyte differentiation_Ikzf1<plstc>/Ikzf1<plstc>
  http://metadb.riken.jp/0008111C57BL6JSfdAnuIkzf1plstcIkzf1plstcIkzf1plstcIkzf1plstc
• lethality throughout fetal growth and development, complete penetrance_Ikzf1<plstc>/Ikzf1<plstc>
  http://metadb.riken.jp/0011099C57BL6JSfdAnuIkzf1plstcIkzf1plstcIkzf1plstcIkzf1plstc
• anemia_Ikzf1<plstc>/Ikzf1<tm2Kge>
  http://metadb.riken.jp/0001577I129S4SvJaeC57BL6C57BL6JSfdAnuIkzf1plstcIkzf1tm2KgeIkzf1plstcIkzf1tm2Kge
• absent pro-B cells_Ikzf1<plstc>/Ikzf1<plstc>
  http://metadb.riken.jp/0008187C57BL6JSfdAnuIkzf1plstcIkzf1plstcIkzf1plstcIkzf1plstc
• decreased erythroid progenitor cell number_Ikzf1<plstc>/Ikzf1<plstc>
  http://metadb.riken.jp/0008973C57BL6JSfdAnuIkzf1plstcIkzf1plstcIkzf1plstcIkzf1plstc
• abnormal erythroblast morphology_Ikzf1<plstc>/Ikzf1<plstc>
  http://metadb.riken.jp/0011176C57BL6JSfdAnuIkzf1plstcIkzf1plstcIkzf1plstcIkzf1plstc
• decreased double-negative T cell number_Ikzf1<plstc>/Ikzf1<+>
  http://metadb.riken.jp/0005089C57BL6JSfdAnuIkzf1plstcIkzf1plstcIkzf1Ikzf1plstcIkzf1
• abnormal myelopoiesis_Ikzf1<plstc>/Ikzf1<plstc>
  http://metadb.riken.jp/0001601C57BL6JSfdAnuIkzf1plstcIkzf1plstcIkzf1plstcIkzf1plstc
• decreased double-positive T cell number_Ikzf1<plstc>/Ikzf1<+>
  http://metadb.riken.jp/0005092C57BL6JSfdAnuIkzf1plstcIkzf1plstcIkzf1Ikzf1plstcIkzf1
• abnormal lymphopoiesis_Ikzf1<plstc>/Ikzf1<+>
  http://metadb.riken.jp/0002401C57BL6JSfdAnuIkzf1plstcIkzf1plstcIkzf1Ikzf1plstcIkzf1
• myeloid hyperplasia_Ikzf1<plstc>/Ikzf1<+>
  http://metadb.riken.jp/0010373C57BL6JSfdAnuIkzf1plstcIkzf1plstcIkzf1Ikzf1plstcIkzf1
• liver hypoplasia_Ikzf1<plstc>/Ikzf1<+>
  http://metadb.riken.jp/0000600C57BL6JSfdAnuIkzf1plstcIkzf1plstcIkzf1Ikzf1plstcIkzf1
• decreased erythrocyte cell number_Ikzf1<plstc>/Ikzf1<plstc>
  http://metadb.riken.jp/0002875C57BL6JSfdAnuIkzf1plstcIkzf1plstcIkzf1plstcIkzf1plstc
• increased T cell derived lymphoma incidence_Ikzf1<plstc>/Ikzf1<+>
  http://metadb.riken.jp/0002024C57BL6JSfdAnuIkzf1plstcIkzf1plstcIkzf1Ikzf1plstcIkzf1
• anemia_Ikzf1<plstc>/Ikzf1<plstc>
  http://metadb.riken.jp/0001577C57BL6JSfdAnuIkzf1plstcIkzf1plstcIkzf1plstcIkzf1plstc
• decreased hematocrit_Ikzf1<plstc>/Ikzf1<plstc>
  http://metadb.riken.jp/0000208C57BL6JSfdAnuIkzf1plstcIkzf1plstcIkzf1plstcIkzf1plstc
• decreased fetal derived definitive erythrocyte cell number_Ikzf1<plstc>/Ikzf1<plstc>
  http://metadb.riken.jp/0011243C57BL6JSfdAnuIkzf1plstcIkzf1plstcIkzf1plstcIkzf1plstc
• abnormal T cell differentiation_Ikzf1<plstc>/Ikzf1<+>
  http://metadb.riken.jp/0002145C57BL6JSfdAnuIkzf1plstcIkzf1plstcIkzf1Ikzf1plstcIkzf1

class

http://purl.org/net/cito/citesAsAuthority

• Ikzf1<plstc>
  http://metadb.riken.jp/db/mgi_rdf/MGI:2669987