Shuhei. Tomita, et.al., Defective brain development in mice lacking the Hif-1alpha gene in neural cells., Molecular and cellular biology, 2003, 23

http://rdf.ncbi.nlm.nih.gov/pubmed/12972594

Shuhei. Tomita, et.al., Defective brain development in mice lacking the Hif-1alpha gene in neural cells., Molecular and cellular biology, 2003, 23

pubmed

allele

http://purl.org/net/cito/citesAsAuthority

• Hif1a<tm1.1Stom>
  http://metadb.riken.jp/db/mgi_rdf/MGI:2677899
• Hif1a<tm1Stom>
  http://metadb.riken.jp/db/mgi_rdf/MGI:2677892

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• abnormal cortical plate morphology_Hif1a<tm1Stom>/Hif1a<tm1.1Stom>,Tg(Nes-cre)1Kag/0
  http://metadb.riken.jp/0008439NSHif1atm1StomHif1atm11StomTgNescre1Kag0Hif1atm11StomTgNescre1KagHif1atm1Stom
• loss of cortex neurons_Hif1a<tm1Stom>/Hif1a<tm1.1Stom>,Tg(Nes-cre)1Kag/0
  http://metadb.riken.jp/0003241NSHif1atm1StomHif1atm11StomTgNescre1Kag0Hif1atm11StomTgNescre1KagHif1atm1Stom
• loss of hippocampal neurons_Hif1a<tm1Stom>/Hif1a<tm1.1Stom>,Tg(Nes-cre)1Kag/0
  http://metadb.riken.jp/0003240NSHif1atm1StomHif1atm11StomTgNescre1Kag0Hif1atm11StomTgNescre1KagHif1atm1Stom
• enlarged lateral ventricles_Hif1a<tm1Stom>/Hif1a<tm1.1Stom>,Tg(Nes-cre)1Kag/0
  http://metadb.riken.jp/0008535NSHif1atm1StomHif1atm11StomTgNescre1Kag0Hif1atm11StomTgNescre1KagHif1atm1Stom
• hydroencephaly_Hif1a<tm1Stom>/Hif1a<tm1.1Stom>,Tg(Nes-cre)1Kag/0
  http://metadb.riken.jp/0001891NSHif1atm1StomHif1atm11StomTgNescre1Kag0Hif1atm11StomTgNescre1KagHif1atm1Stom
• abnormal cerebral cortex morphology_Hif1a<tm1Stom>/Hif1a<tm1.1Stom>,Tg(Nes-cre)1Kag/0
  http://metadb.riken.jp/0000788NSHif1atm1StomHif1atm11StomTgNescre1Kag0Hif1atm11StomTgNescre1KagHif1atm1Stom
• abnormal spatial learning_Hif1a<tm1Stom>/Hif1a<tm1.1Stom>,Tg(Nes-cre)1Kag/0
  http://metadb.riken.jp/0001463NSHif1atm1StomHif1atm11StomTgNescre1Kag0Hif1atm11StomTgNescre1KagHif1atm1Stom
• abnormal occipital lobe morphology_Hif1a<tm1Stom>/Hif1a<tm1.1Stom>,Tg(Nes-cre)1Kag/0
  http://metadb.riken.jp/0000804NSHif1atm1StomHif1atm11StomTgNescre1Kag0Hif1atm11StomTgNescre1KagHif1atm1Stom
• abnormal cerebral hemisphere morphology_Hif1a<tm1Stom>/Hif1a<tm1.1Stom>,Tg(Nes-cre)1Kag/0
  http://metadb.riken.jp/0008540NSHif1atm1StomHif1atm11StomTgNescre1Kag0Hif1atm11StomTgNescre1KagHif1atm1Stom
• prenatal lethality, complete penetrance_Hif1a<tm1.1Stom>/Hif1a<tm1.1Stom>
  http://metadb.riken.jp/0011091NSHif1atm11StomHif1atm11StomHif1atm11Stom
• abnormal temporal lobe morphology_Hif1a<tm1Stom>/Hif1a<tm1.1Stom>,Tg(Nes-cre)1Kag/0
  http://metadb.riken.jp/0000801NSHif1atm1StomHif1atm11StomTgNescre1Kag0Hif1atm11StomTgNescre1KagHif1atm1Stom

class

http://purl.org/net/cito/citesAsAuthority

• Hif1a<tm1.1Stom>
  http://metadb.riken.jp/db/mgi_rdf/MGI:2677899
• Hif1a<tm1Stom>
  http://metadb.riken.jp/db/mgi_rdf/MGI:2677892