Suzana. Gispert, et.al., Transgenic mice expressing mutant A53T human alpha-synuclein show neuronal dysfunction in the absence of aggregate formation., Molecular and cellular neurosciences, 2003, 24

http://rdf.ncbi.nlm.nih.gov/pubmed/14572463

Suzana. Gispert, et.al., Transgenic mice expressing mutant A53T human alpha-synuclein show neuronal dysfunction in the absence of aggregate formation., Molecular and cellular neurosciences, 2003, 24

pubmed

allele

http://purl.org/net/cito/citesAsAuthority

• Tg(SNCA)1Nbm
  http://metadb.riken.jp/db/mgi_rdf/MGI:4412055
• Tg(Prnp-SNCA*A53T)AAub
  http://metadb.riken.jp/db/mgi_rdf/MGI:3723258

class

http://purl.org/net/cito/citesAsAuthority

• Tg(SNCA)1Nbm
  http://metadb.riken.jp/db/mgi_rdf/MGI:4412055
• Tg(Prnp-SNCA*A53T)AAub
  http://metadb.riken.jp/db/mgi_rdf/MGI:3723258

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• neurodegeneration_Tg(Prnp-SNCA*A53T)AAub/Tg(Prnp-SNCA*A53T)AAub
  http://metadb.riken.jp/0002229IFVBNTgPrnpSNCAA53TAAubTgPrnpSNCAA53TAAubTgPrnpSNCAA53TAAub
• weakness_Tg(Prnp-SNCA*A53T)AAub/Tg(Prnp-SNCA*A53T)AAub
  http://metadb.riken.jp/0000746IFVBNTgPrnpSNCAA53TAAubTgPrnpSNCAA53TAAubTgPrnpSNCAA53TAAub
• decreased vertical activity_Tg(Prnp-SNCA*A53T)AAub/Tg(Prnp-SNCA*A53T)AAub
  http://metadb.riken.jp/0002757IFVBNTgPrnpSNCAA53TAAubTgPrnpSNCAA53TAAubTgPrnpSNCAA53TAAub
• decreased grip strength_Tg(Prnp-SNCA*A53T)AAub/Tg(Prnp-SNCA*A53T)AAub
  http://metadb.riken.jp/0010053IFVBNTgPrnpSNCAA53TAAubTgPrnpSNCAA53TAAubTgPrnpSNCAA53TAAub
• impaired coordination_Tg(Prnp-SNCA*A53T)AAub/Tg(Prnp-SNCA*A53T)AAub
  http://metadb.riken.jp/0001405IFVBNTgPrnpSNCAA53TAAubTgPrnpSNCAA53TAAubTgPrnpSNCAA53TAAub
• abnormal neurite morphology_Tg(Prnp-SNCA*A53T)AAub/Tg(Prnp-SNCA*A53T)AAub
  http://metadb.riken.jp/0008415IFVBNTgPrnpSNCAA53TAAubTgPrnpSNCAA53TAAubTgPrnpSNCAA53TAAub
• short stride length_Tg(Prnp-SNCA*A53T)AAub/Tg(Prnp-SNCA*A53T)AAub
  http://metadb.riken.jp/0001407IFVBNTgPrnpSNCAA53TAAubTgPrnpSNCAA53TAAubTgPrnpSNCAA53TAAub