Satoru. Yamazaki, et.al., Mice with defects in HB-EGF ectodomain shedding show severe developmental abnormalities., The Journal of cell biology, 2003, 163

http://rdf.ncbi.nlm.nih.gov/pubmed/14597776

http://rdf.ncbi.nlm.nih.gov/pubmed/14597776

pubmed

allele

http://purl.org/net/cito/citesAsAuthority

• Hbegf<tm3Mek>
  http://metadb.riken.jp/db/mgi_rdf/MGI:2682961
• Hbegf<tm2Mek>
  http://metadb.riken.jp/db/mgi_rdf/MGI:2682958

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• perinatal lethality, incomplete penetrance_Hbegf<tm3Mek>/Hbegf<+>
  http://metadb.riken.jp/0011090I129SvC57BL6CBAHbegftm3MekHbegfHbegfHbegftm3Mek
• abnormal semilunar valve morphology_Hbegf<tm2Mek>/Hbegf<tm2Mek>
  http://metadb.riken.jp/0002746I129SvC57BL6CBAHbegftm2MekHbegftm2MekHbegftm2Mek
• dilated cardiomyopathy_Hbegf<tm2Mek>/Hbegf<tm2Mek>
  http://metadb.riken.jp/0002795I129SvC57BL6CBAHbegftm2MekHbegftm2MekHbegftm2Mek
• abnormal cardiovascular system physiology_Hbegf<tm2Mek>/Hbegf<tm2Mek>
  http://metadb.riken.jp/0001544I129SvC57BL6CBAHbegftm2MekHbegftm2MekHbegftm2Mek
• thick epidermis_Hbegf<tm3Mek>/Hbegf<+>
  http://metadb.riken.jp/0001219I129SvC57BL6CBAHbegftm3MekHbegfHbegfHbegftm3Mek
• decreased cardiac muscle contractility_Hbegf<tm2Mek>/Hbegf<tm2Mek>
  http://metadb.riken.jp/0005140I129SvC57BL6CBAHbegftm2MekHbegftm2MekHbegftm2Mek
• abnormal cardiovascular system morphology_Hbegf<tm2Mek>/Hbegf<tm2Mek>
  http://metadb.riken.jp/0002127I129SvC57BL6CBAHbegftm2MekHbegftm2MekHbegftm2Mek
• thin myocardium_Hbegf<tm2Mek>/Hbegf<tm2Mek>
  http://metadb.riken.jp/0002652I129SvC57BL6CBAHbegftm2MekHbegftm2MekHbegftm2Mek
• premature death_Hbegf<tm2Mek>/Hbegf<tm2Mek>
  http://metadb.riken.jp/0002083I129SvC57BL6CBAHbegftm2MekHbegftm2MekHbegftm2Mek
• abnormal myocardial fiber morphology_Hbegf<tm3Mek>/Hbegf<+>
  http://metadb.riken.jp/0000278I129SvC57BL6CBAHbegftm3MekHbegfHbegfHbegftm3Mek
• cardiac hypertrophy_Hbegf<tm3Mek>/Hbegf<+>
  http://metadb.riken.jp/0001625I129SvC57BL6CBAHbegftm3MekHbegfHbegfHbegftm3Mek
• enlarged heart_Hbegf<tm2Mek>/Hbegf<tm2Mek>
  http://metadb.riken.jp/0000274I129SvC57BL6CBAHbegftm2MekHbegftm2MekHbegftm2Mek
• decreased body size_Hbegf<tm3Mek>/Hbegf<+>
  http://metadb.riken.jp/0001265I129SvC57BL6CBAHbegftm3MekHbegfHbegfHbegftm3Mek
• abnormal heart size_Hbegf<tm2Mek>/Hbegf<tm2Mek>
  http://metadb.riken.jp/0005406I129SvC57BL6CBAHbegftm2MekHbegftm2MekHbegftm2Mek
• cardiac fibrosis_Hbegf<tm2Mek>/Hbegf<tm2Mek>
  http://metadb.riken.jp/0003141I129SvC57BL6CBAHbegftm2MekHbegftm2MekHbegftm2Mek
• abnormal heart valve morphology_Hbegf<tm2Mek>/Hbegf<tm2Mek>
  http://metadb.riken.jp/0000285I129SvC57BL6CBAHbegftm2MekHbegftm2MekHbegftm2Mek
• abnormal atrioventricular valve morphology_Hbegf<tm2Mek>/Hbegf<tm2Mek>
  http://metadb.riken.jp/0002745I129SvC57BL6CBAHbegftm2MekHbegftm2MekHbegftm2Mek

class

http://purl.org/net/cito/citesAsAuthority

• Hbegf<tm3Mek>
  http://metadb.riken.jp/db/mgi_rdf/MGI:2682961
• Hbegf<tm2Mek>
  http://metadb.riken.jp/db/mgi_rdf/MGI:2682958