Maria Teresa. Discenza, et.al., WT1 is a modifier of the Pax2 mutant phenotype: cooperation and interaction between WT1 and Pax2., Oncogene, 2003, 22

http://rdf.ncbi.nlm.nih.gov/pubmed/14603255

Maria Teresa. Discenza, et.al., WT1 is a modifier of the Pax2 mutant phenotype: cooperation and interaction between WT1 and Pax2., Oncogene, 2003, 22

pubmed

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• postnatal lethality, incomplete penetrance_Pax2<1Neu>/Pax2<+>,Wt1<tm1Jae>/Wt1<+>
  http://metadb.riken.jp/0011086I102129S4SvJaeC57BL6Pax21NeuPax2Wt1tm1JaeWt1Pax2Pax21NeuWt1tm1JaeWt1
• small kidney_Pax2<1Neu>/Pax2<+>,Wt1<tm1Jae>/Wt1<+>
  http://metadb.riken.jp/0002989I102129S4SvJaeC57BL6Pax21NeuPax2Wt1tm1JaeWt1Pax2Pax21NeuWt1tm1JaeWt1
• increased kidney apoptosis_Pax2<1Neu>/Pax2<+>,Wt1<tm1Jae>/Wt1<+>
  http://metadb.riken.jp/0011368I102129S4SvJaeC57BL6Pax21NeuPax2Wt1tm1JaeWt1Pax2Pax21NeuWt1tm1JaeWt1
• kidney medulla hypoplasia_Pax2<1Neu>/Pax2<+>,Wt1<tm1Jae>/Wt1<+>
  http://metadb.riken.jp/0003626I102129S4SvJaeC57BL6Pax21NeuPax2Wt1tm1JaeWt1Pax2Pax21NeuWt1tm1JaeWt1
• abnormal kidney development_Pax2<1Neu>/Pax2<+>,Wt1<tm1Jae>/Wt1<+>
  http://metadb.riken.jp/0000527I102129S4SvJaeC57BL6Pax21NeuPax2Wt1tm1JaeWt1Pax2Pax21NeuWt1tm1JaeWt1
• decreased nephron number_Pax2<1Neu>/Pax2<+>
  http://metadb.riken.jp/0011290I102C57BL6Pax21NeuPax2Pax2Pax21Neu
• absent kidney_Pax2<1Neu>/Pax2<+>
  http://metadb.riken.jp/0000520I102C57BL6Pax21NeuPax2Pax2Pax21Neu
• decreased nephron number_Pax2<1Neu>/Pax2<+>,Wt1<tm1Jae>/Wt1<+>
  http://metadb.riken.jp/0011290I102129S4SvJaeC57BL6Pax21NeuPax2Wt1tm1JaeWt1Pax2Pax21NeuWt1tm1JaeWt1
• decreased renal glomerulus number_Pax2<1Neu>/Pax2<+>
  http://metadb.riken.jp/0004505I102C57BL6Pax21NeuPax2Pax2Pax21Neu
• abnormal kidney calyx morphology_Pax2<1Neu>/Pax2<+>,Wt1<tm1Jae>/Wt1<+>
  http://metadb.riken.jp/0004195I102129S4SvJaeC57BL6Pax21NeuPax2Wt1tm1JaeWt1Pax2Pax21NeuWt1tm1JaeWt1
• increased kidney apoptosis_Pax2<1Neu>/Pax2<+>
  http://metadb.riken.jp/0011368I102C57BL6Pax21NeuPax2Pax2Pax21Neu
• decreased renal glomerulus number_Pax2<1Neu>/Pax2<+>,Wt1<tm1Jae>/Wt1<+>
  http://metadb.riken.jp/0004505I102129S4SvJaeC57BL6Pax21NeuPax2Wt1tm1JaeWt1Pax2Pax21NeuWt1tm1JaeWt1
• postnatal lethality, incomplete penetrance_Pax2<1Neu>/Pax2<+>
  http://metadb.riken.jp/0011086I102C57BL6Pax21NeuPax2Pax2Pax21Neu
• lethality throughout fetal growth and development, incomplete penetrance_Pax2<1Neu>/Pax2<+>
  http://metadb.riken.jp/0011109I102C57BL6Pax21NeuPax2Pax2Pax21Neu
• small kidney_Pax2<1Neu>/Pax2<+>
  http://metadb.riken.jp/0002989I102C57BL6Pax21NeuPax2Pax2Pax21Neu
• absent kidney_Pax2<1Neu>/Pax2<+>,Wt1<tm1Jae>/Wt1<+>
  http://metadb.riken.jp/0000520I102129S4SvJaeC57BL6Pax21NeuPax2Wt1tm1JaeWt1Pax2Pax21NeuWt1tm1JaeWt1
• abnormal kidney development_Pax2<1Neu>/Pax2<+>
  http://metadb.riken.jp/0000527I102C57BL6Pax21NeuPax2Pax2Pax21Neu
• lethality throughout fetal growth and development, incomplete penetrance_Pax2<1Neu>/Pax2<+>,Wt1<tm1Jae>/Wt1<+>
  http://metadb.riken.jp/0011109I102129S4SvJaeC57BL6Pax21NeuPax2Wt1tm1JaeWt1Pax2Pax21NeuWt1tm1JaeWt1
• abnormal kidney collecting duct morphology_Pax2<1Neu>/Pax2<+>,Wt1<tm1Jae>/Wt1<+>
  http://metadb.riken.jp/0004754I102129S4SvJaeC57BL6Pax21NeuPax2Wt1tm1JaeWt1Pax2Pax21NeuWt1tm1JaeWt1