Qingde. Wang, et.al., Stress-induced apoptosis associated with null mutation of ADAR1 RNA editing deaminase gene., The Journal of biological chemistry, 2004, 279

http://rdf.ncbi.nlm.nih.gov/pubmed/14613934

Qingde. Wang, et.al., Stress-induced apoptosis associated with null mutation of ADAR1 RNA editing deaminase gene., The Journal of biological chemistry, 2004, 279

pubmed

allele

http://purl.org/net/cito/citesAsAuthority

• Adar<tm1Knk>
  http://metadb.riken.jp/db/mgi_rdf/MGI:3032439
• Adar<tm1.1Knk>
  http://metadb.riken.jp/db/mgi_rdf/MGI:3032487

class

http://purl.org/net/cito/citesAsAuthority

• Adar<tm1Knk>
  http://metadb.riken.jp/db/mgi_rdf/MGI:3032439
• Adar<tm1.1Knk>
  http://metadb.riken.jp/db/mgi_rdf/MGI:3032487

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• decreased body size_Adar<tm1Knk>/Adar<tm1Knk>,Tg(Alb-cre)21Mgn/0
  http://metadb.riken.jp/0001265I129S1Sv129X1SvJC57BL6DBAAdartm1KnkAdartm1KnkTgAlbcre21Mgn0Adartm1KnkTgAlbcre21Mgn
• increased lactate dehydrogenase level_Adar<tm1Knk>/Adar<tm1Knk>,Tg(Alb-cre)21Mgn/0
  http://metadb.riken.jp/0002944I129S1Sv129X1SvJC57BL6DBAAdartm1KnkAdartm1KnkTgAlbcre21Mgn0Adartm1KnkTgAlbcre21Mgn
• embryonic lethality during organogenesis, complete penetrance_Adar<tm1.1Knk>/Adar<tm1.1Knk>
  http://metadb.riken.jp/0011098I129S1Sv129X1SvJAdartm11KnkAdartm11KnkAdartm11Knk
• hyperglycemia_Adar<tm1Knk>/Adar<tm1Knk>,Tg(Alb-cre)21Mgn/0
  http://metadb.riken.jp/0001559I129S1Sv129X1SvJC57BL6DBAAdartm1KnkAdartm1KnkTgAlbcre21Mgn0Adartm1KnkTgAlbcre21Mgn
• increased sensitivity to induced cell death_Adar<tm1.1Knk>/Adar<tm1.1Knk>
  http://metadb.riken.jp/0008943I129S1Sv129X1SvJAdartm11KnkAdartm11KnkAdartm11Knk
• increased hepatocyte apoptosis_Adar<tm1Knk>/Adar<tm1Knk>,Tg(Alb-cre)21Mgn/0
  http://metadb.riken.jp/0003887I129S1Sv129X1SvJC57BL6DBAAdartm1KnkAdartm1KnkTgAlbcre21Mgn0Adartm1KnkTgAlbcre21Mgn
• increased circulating alkaline phosphatase level_Adar<tm1Knk>/Adar<tm1Knk>,Tg(Alb-cre)21Mgn/0
  http://metadb.riken.jp/0002968I129S1Sv129X1SvJC57BL6DBAAdartm1KnkAdartm1KnkTgAlbcre21Mgn0Adartm1KnkTgAlbcre21Mgn
• pale yolk sac_Adar<tm1.1Knk>/Adar<tm1.1Knk>
  http://metadb.riken.jp/0001722I129S1Sv129X1SvJAdartm11KnkAdartm11KnkAdartm11Knk
• abnormal apoptosis_Adar<tm1.1Knk>/Adar<tm1.1Knk>
  http://metadb.riken.jp/0001648I129S1Sv129X1SvJAdartm11KnkAdartm11KnkAdartm11Knk
• increased embryonic tissue cell apoptosis_Adar<tm1.1Knk>/Adar<tm1.1Knk>
  http://metadb.riken.jp/0013504I129S1Sv129X1SvJAdartm11KnkAdartm11KnkAdartm11Knk
• increased circulating alanine transaminase level_Adar<tm1Knk>/Adar<tm1Knk>,Tg(Alb-cre)21Mgn/0
  http://metadb.riken.jp/0002941I129S1Sv129X1SvJC57BL6DBAAdartm1KnkAdartm1KnkTgAlbcre21Mgn0Adartm1KnkTgAlbcre21Mgn
• abnormal liver morphology_Adar<tm1Knk>/Adar<tm1Knk>,Tg(Alb-cre)21Mgn/0
  http://metadb.riken.jp/0000598I129S1Sv129X1SvJC57BL6DBAAdartm1KnkAdartm1KnkTgAlbcre21Mgn0Adartm1KnkTgAlbcre21Mgn
• increased hepatocyte apoptosis_Adar<tm1.1Knk>/Adar<tm1.1Knk>
  http://metadb.riken.jp/0003887I129S1Sv129X1SvJAdartm11KnkAdartm11KnkAdartm11Knk
• increased circulating aspartate transaminase level_Adar<tm1Knk>/Adar<tm1Knk>,Tg(Alb-cre)21Mgn/0
  http://metadb.riken.jp/0005343I129S1Sv129X1SvJC57BL6DBAAdartm1KnkAdartm1KnkTgAlbcre21Mgn0Adartm1KnkTgAlbcre21Mgn
• abnormal circulating enzyme level_Adar<tm1Knk>/Adar<tm1Knk>,Tg(Alb-cre)21Mgn/0
  http://metadb.riken.jp/0001570I129S1Sv129X1SvJC57BL6DBAAdartm1KnkAdartm1KnkTgAlbcre21Mgn0Adartm1KnkTgAlbcre21Mgn
• hemorrhage_Adar<tm1.1Knk>/Adar<tm1.1Knk>
  http://metadb.riken.jp/0001914I129S1Sv129X1SvJAdartm11KnkAdartm11KnkAdartm11Knk