Isamu. Hokuto, et.al., Stat-3 is required for pulmonary homeostasis during hyperoxia., The Journal of clinical investigation, 2004, 113

http://rdf.ncbi.nlm.nih.gov/pubmed/14702106

Isamu. Hokuto, et.al., Stat-3 is required for pulmonary homeostasis during hyperoxia., The Journal of clinical investigation, 2004, 113

pubmed

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• abnormal cytokine level_Stat3<tm2Aki>/Stat3<tm2Aki>,Tg(SFTPC-rtTA)5Jaw/0,Tg(tetO-cre)1Jaw/0
  http://metadb.riken.jp/0008713I129129P2OlaHsdC57BL6Stat3tm2AkiStat3tm2AkiTgSFTPCrtTA5Jaw0TgtetOcre1Jaw0TgtetOcre1JawStat3tm2AkiTgSFTPCrtTA5Jaw
• lung inflammation_Stat3<tm2Aki>/Stat3<tm2Aki>,Tg(SFTPC-rtTA)5Jaw/0,Tg(tetO-cre)1Jaw/0
  http://metadb.riken.jp/0001861I129129P2OlaHsdC57BL6Stat3tm2AkiStat3tm2AkiTgSFTPCrtTA5Jaw0TgtetOcre1Jaw0TgtetOcre1JawStat3tm2AkiTgSFTPCrtTA5Jaw
• increased lung tissue damping_Stat3<tm2Aki>/Stat3<tm2Aki>,Tg(SFTPC-rtTA)5Jaw/0,Tg(tetO-cre)1Jaw/0
  http://metadb.riken.jp/0011047I129129P2OlaHsdC57BL6Stat3tm2AkiStat3tm2AkiTgSFTPCrtTA5Jaw0TgtetOcre1Jaw0TgtetOcre1JawStat3tm2AkiTgSFTPCrtTA5Jaw
• respiratory distress_Stat3<tm2Aki>/Stat3<tm2Aki>,Tg(SFTPC-rtTA)5Jaw/0,Tg(tetO-cre)1Jaw/0
  http://metadb.riken.jp/0001954I129129P2OlaHsdC57BL6Stat3tm2AkiStat3tm2AkiTgSFTPCrtTA5Jaw0TgtetOcre1Jaw0TgtetOcre1JawStat3tm2AkiTgSFTPCrtTA5Jaw
• pulmonary epithelial necrosis_Stat3<tm2Aki>/Stat3<tm2Aki>,Tg(SFTPC-rtTA)5Jaw/0,Tg(tetO-cre)1Jaw/0
  http://metadb.riken.jp/0010858I129129P2OlaHsdC57BL6Stat3tm2AkiStat3tm2AkiTgSFTPCrtTA5Jaw0TgtetOcre1Jaw0TgtetOcre1JawStat3tm2AkiTgSFTPCrtTA5Jaw
• abnormal respiratory mechanics_Stat3<tm2Aki>/Stat3<tm2Aki>,Tg(SFTPC-rtTA)5Jaw/0,Tg(tetO-cre)1Jaw/0
  http://metadb.riken.jp/0002314I129129P2OlaHsdC57BL6Stat3tm2AkiStat3tm2AkiTgSFTPCrtTA5Jaw0TgtetOcre1Jaw0TgtetOcre1JawStat3tm2AkiTgSFTPCrtTA5Jaw
• increased airway resistance_Stat3<tm2Aki>/Stat3<tm2Aki>,Tg(SFTPC-rtTA)5Jaw/0,Tg(tetO-cre)1Jaw/0
  http://metadb.riken.jp/0010935I129129P2OlaHsdC57BL6Stat3tm2AkiStat3tm2AkiTgSFTPCrtTA5Jaw0TgtetOcre1Jaw0TgtetOcre1JawStat3tm2AkiTgSFTPCrtTA5Jaw
• increased lung elastance_Stat3<tm2Aki>/Stat3<tm2Aki>,Tg(SFTPC-rtTA)5Jaw/0,Tg(tetO-cre)1Jaw/0
  http://metadb.riken.jp/0011044I129129P2OlaHsdC57BL6Stat3tm2AkiStat3tm2AkiTgSFTPCrtTA5Jaw0TgtetOcre1Jaw0TgtetOcre1JawStat3tm2AkiTgSFTPCrtTA5Jaw
• pulmonary hyaline membrane formation_Stat3<tm2Aki>/Stat3<tm2Aki>,Tg(SFTPC-rtTA)5Jaw/0,Tg(tetO-cre)1Jaw/0
  http://metadb.riken.jp/0011018I129129P2OlaHsdC57BL6Stat3tm2AkiStat3tm2AkiTgSFTPCrtTA5Jaw0TgtetOcre1Jaw0TgtetOcre1JawStat3tm2AkiTgSFTPCrtTA5Jaw
• respiratory failure_Stat3<tm2Aki>/Stat3<tm2Aki>,Tg(SFTPC-rtTA)5Jaw/0,Tg(tetO-cre)1Jaw/0
  http://metadb.riken.jp/0001953I129129P2OlaHsdC57BL6Stat3tm2AkiStat3tm2AkiTgSFTPCrtTA5Jaw0TgtetOcre1Jaw0TgtetOcre1JawStat3tm2AkiTgSFTPCrtTA5Jaw
• abnormal lung vasculature morphology_Stat3<tm2Aki>/Stat3<tm2Aki>,Tg(SFTPC-rtTA)5Jaw/0,Tg(tetO-cre)1Jaw/0
  http://metadb.riken.jp/0004007I129129P2OlaHsdC57BL6Stat3tm2AkiStat3tm2AkiTgSFTPCrtTA5Jaw0TgtetOcre1Jaw0TgtetOcre1JawStat3tm2AkiTgSFTPCrtTA5Jaw
• decreased lung compliance_Stat3<tm2Aki>/Stat3<tm2Aki>,Tg(SFTPC-rtTA)5Jaw/0,Tg(tetO-cre)1Jaw/0
  http://metadb.riken.jp/0010896I129129P2OlaHsdC57BL6Stat3tm2AkiStat3tm2AkiTgSFTPCrtTA5Jaw0TgtetOcre1Jaw0TgtetOcre1JawStat3tm2AkiTgSFTPCrtTA5Jaw
• abnormal pulmonary alveolus epithelial cell morphology_Stat3<tm2Aki>/Stat3<tm2Aki>,Tg(SFTPC-rtTA)5Jaw/0,Tg(tetO-cre)1Jaw/0
  http://metadb.riken.jp/0002273I129129P2OlaHsdC57BL6Stat3tm2AkiStat3tm2AkiTgSFTPCrtTA5Jaw0TgtetOcre1Jaw0TgtetOcre1JawStat3tm2AkiTgSFTPCrtTA5Jaw
• abnormal surfactant secretion_Stat3<tm2Aki>/Stat3<tm2Aki>,Tg(SFTPC-rtTA)5Jaw/0,Tg(tetO-cre)1Jaw/0
  http://metadb.riken.jp/0004780I129129P2OlaHsdC57BL6Stat3tm2AkiStat3tm2AkiTgSFTPCrtTA5Jaw0TgtetOcre1Jaw0TgtetOcre1JawStat3tm2AkiTgSFTPCrtTA5Jaw
• increased susceptibility to injury_Stat3<tm2Aki>/Stat3<tm2Aki>,Tg(SFTPC-rtTA)5Jaw/0,Tg(tetO-cre)1Jaw/0
  http://metadb.riken.jp/0005165I129129P2OlaHsdC57BL6Stat3tm2AkiStat3tm2AkiTgSFTPCrtTA5Jaw0TgtetOcre1Jaw0TgtetOcre1JawStat3tm2AkiTgSFTPCrtTA5Jaw
• decreased type II pneumocyte number_Stat3<tm2Aki>/Stat3<tm2Aki>,Tg(SFTPC-rtTA)5Jaw/0,Tg(tetO-cre)1Jaw/0
  http://metadb.riken.jp/0010811I129129P2OlaHsdC57BL6Stat3tm2AkiStat3tm2AkiTgSFTPCrtTA5Jaw0TgtetOcre1Jaw0TgtetOcre1JawStat3tm2AkiTgSFTPCrtTA5Jaw