Laurie K. Russell, et.al., Cardiac-specific induction of the transcriptional coactivator peroxisome proliferator-activated receptor gamma coactivator-1alpha promotes mitochondrial biogenesis and reversible cardiomyopathy in a developmental stage-dependent manner., Circulation research, 2004, 94

http://rdf.ncbi.nlm.nih.gov/pubmed/14726475

Laurie K. Russell, et.al., Cardiac-specific induction of the transcriptional coactivator peroxisome proliferator-activated receptor gamma coactivator-1alpha promotes mitochondrial biogenesis and reversible cardiomyopathy in a developmental stage-dependent manner., Circulation research, 2004, 94

pubmed

allele

http://purl.org/net/cito/citesAsAuthority

• Tg(tetO-Ppargc1a)1Dpk
  http://metadb.riken.jp/db/mgi_rdf/MGI:4429485

class

http://purl.org/net/cito/citesAsAuthority

• Tg(tetO-Ppargc1a)1Dpk
  http://metadb.riken.jp/db/mgi_rdf/MGI:4429485

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• abnormal myocardial fiber morphology_Tg(Myh6-rtTA)8585Jam/0,Tg(tetO-Ppargc1a)1Dpk/0
  http://metadb.riken.jp/0000278IFVBNFVBNTacTgMyh6rtTA8585Jam0TgtetOPpargc1a1Dpk0TgMyh6rtTA8585JamTgtetOPpargc1a1Dpk
• cardiac hypertrophy_Tg(Myh6-rtTA)8585Jam/0,Tg(tetO-Ppargc1a)1Dpk/0
  http://metadb.riken.jp/0001625IFVBNFVBNTacTgMyh6rtTA8585Jam0TgtetOPpargc1a1Dpk0TgMyh6rtTA8585JamTgtetOPpargc1a1Dpk
• dilated heart left ventricle_Tg(Myh6-rtTA)8585Jam/0,Tg(tetO-Ppargc1a)1Dpk/0
  http://metadb.riken.jp/0002753IFVBNFVBNTacTgMyh6rtTA8585Jam0TgtetOPpargc1a1Dpk0TgMyh6rtTA8585JamTgtetOPpargc1a1Dpk
• decreased heart rate_Tg(Myh6-rtTA)8585Jam/0,Tg(tetO-Ppargc1a)1Dpk/0
  http://metadb.riken.jp/0005333IFVBNFVBNTacTgMyh6rtTA8585Jam0TgtetOPpargc1a1Dpk0TgMyh6rtTA8585JamTgtetOPpargc1a1Dpk
• decreased cardiac muscle contractility_Tg(Myh6-rtTA)8585Jam/0,Tg(tetO-Ppargc1a)1Dpk/0
  http://metadb.riken.jp/0005140IFVBNFVBNTacTgMyh6rtTA8585Jam0TgtetOPpargc1a1Dpk0TgMyh6rtTA8585JamTgtetOPpargc1a1Dpk
• cardiomyopathy_Tg(Myh6-rtTA)8585Jam/0,Tg(tetO-Ppargc1a)1Dpk/0
  http://metadb.riken.jp/0005330IFVBNFVBNTacTgMyh6rtTA8585Jam0TgtetOPpargc1a1Dpk0TgMyh6rtTA8585JamTgtetOPpargc1a1Dpk
• abnormal heart left ventricle morphology_Tg(Myh6-rtTA)8585Jam/0,Tg(tetO-Ppargc1a)1Dpk/0
  http://metadb.riken.jp/0003921IFVBNFVBNTacTgMyh6rtTA8585Jam0TgtetOPpargc1a1Dpk0TgMyh6rtTA8585JamTgtetOPpargc1a1Dpk
• abnormal mitochondrion morphology_Tg(Myh6-rtTA)8585Jam/0,Tg(tetO-Ppargc1a)1Dpk/0
  http://metadb.riken.jp/0006035IFVBNFVBNTacTgMyh6rtTA8585Jam0TgtetOPpargc1a1Dpk0TgMyh6rtTA8585JamTgtetOPpargc1a1Dpk
• increased heart rate_Tg(Myh6-rtTA)8585Jam/0,Tg(tetO-Ppargc1a)1Dpk/0
  http://metadb.riken.jp/0002626IFVBNFVBNTacTgMyh6rtTA8585Jam0TgtetOPpargc1a1Dpk0TgMyh6rtTA8585JamTgtetOPpargc1a1Dpk
• dilated heart right ventricle_Tg(Myh6-rtTA)8585Jam/0,Tg(tetO-Ppargc1a)1Dpk/0
  http://metadb.riken.jp/0002754IFVBNFVBNTacTgMyh6rtTA8585Jam0TgtetOPpargc1a1Dpk0TgMyh6rtTA8585JamTgtetOPpargc1a1Dpk
• increased mitochondrial fission_Tg(Myh6-rtTA)8585Jam/0,Tg(tetO-Ppargc1a)1Dpk/0
  http://metadb.riken.jp/0006038IFVBNFVBNTacTgMyh6rtTA8585Jam0TgtetOPpargc1a1Dpk0TgMyh6rtTA8585JamTgtetOPpargc1a1Dpk