Jacqueline A. Taylor, et.al., A spontaneous model for autoimmune myocarditis using the human MHC molecule HLA-DQ8., Journal of immunology (Baltimore, Md. : 1950), 2004, 172

http://rdf.ncbi.nlm.nih.gov/pubmed/14764740

Jacqueline A. Taylor, et.al., A spontaneous model for autoimmune myocarditis using the human MHC molecule HLA-DQ8., Journal of immunology (Baltimore, Md. : 1950), 2004, 172

pubmed

allele

http://purl.org/net/cito/citesAsAuthority

• Tg(HLA-DQA1,HLA-DQB1)73Myl
  http://metadb.riken.jp/db/mgi_rdf/MGI:3687023
• Tg(HLA-DQA1,HLA-DQB1)70Myl
  http://metadb.riken.jp/db/mgi_rdf/MGI:3687022

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• enlarged heart_H2-Ab1<tm1Gru>/H2-Ab1<tm1Gru>,Tg(HLA-DQA1,HLA-DQB1)73Myl/0
  http://metadb.riken.jp/0000274NODCgH2Ab1tm1GruTgHLADQA1HLADQB173MylH2Ab1tm1GruH2Ab1tm1GruTgHLADQA1HLADQB173Myl0TgHLADQA1HLADQB173MylH2Ab1tm1Gru
• insulitis_H2-Ab1<tm1Gru>/H2-Ab1<tm1Gru>,Tg(HLA-DQA1,HLA-DQB1)70Myl/0
  http://metadb.riken.jp/0004031NODCgH2Ab1tm1GruTgHLADQA1HLADQB170MylH2Ab1tm1GruH2Ab1tm1GruTgHLADQA1HLADQB170Myl0TgHLADQA1HLADQB170MylH2Ab1tm1Gru
• abnormal heart ventricle morphology_H2-Ab1<tm1Gru>/H2-Ab1<tm1Gru>,Tg(HLA-DQA1,HLA-DQB1)73Myl/0
  http://metadb.riken.jp/0005294NODCgH2Ab1tm1GruTgHLADQA1HLADQB173MylH2Ab1tm1GruH2Ab1tm1GruTgHLADQA1HLADQB173Myl0TgHLADQA1HLADQB173MylH2Ab1tm1Gru
• pleural effusion_H2-Ab1<tm1Gru>/H2-Ab1<tm1Gru>,Tg(HLA-DQA1,HLA-DQB1)73Myl/0
  http://metadb.riken.jp/0010334NODCgH2Ab1tm1GruTgHLADQA1HLADQB173MylH2Ab1tm1GruH2Ab1tm1GruTgHLADQA1HLADQB173Myl0TgHLADQA1HLADQB173MylH2Ab1tm1Gru
• heart inflammation_H2-Ab1<tm1Gru>/H2-Ab1<tm1Gru>,Tg(HLA-DQA1,HLA-DQB1)73Myl/0
  http://metadb.riken.jp/0001853NODCgH2Ab1tm1GruTgHLADQA1HLADQB173MylH2Ab1tm1GruH2Ab1tm1GruTgHLADQA1HLADQB173Myl0TgHLADQA1HLADQB173MylH2Ab1tm1Gru
• myocarditis_H2-Ab1<tm1Gru>/H2-Ab1<tm1Gru>,Rag1<tm1Mom>/Rag1<tm1Mom>,Tg(HLA-DQA1,HLA-DQB1)73Myl/0
  http://metadb.riken.jp/0001856NODCgRag1tm1MomH2Ab1tm1GruTgHLADQA1HLADQB173MylH2Ab1tm1GruH2Ab1tm1GruRag1tm1MomRag1tm1MomTgHLADQA1HLADQB173Myl0TgHLADQA1HLADQB173MylH2Ab1tm1GruRag1tm1Mom
• insulitis_H2-Ab1<tm1Gru>/H2-Ab1<tm1Gru>,Tg(HLA-DQA1,HLA-DQB1)73Myl/0
  http://metadb.riken.jp/0004031NODCgH2Ab1tm1GruTgHLADQA1HLADQB173MylH2Ab1tm1GruH2Ab1tm1GruTgHLADQA1HLADQB173Myl0TgHLADQA1HLADQB173MylH2Ab1tm1Gru
• myocardial necrosis_H2-Ab1<tm1Gru>/H2-Ab1<tm1Gru>,Tg(HLA-DQA1,HLA-DQB1)70Myl/0
  http://metadb.riken.jp/0006085NODCgH2Ab1tm1GruTgHLADQA1HLADQB170MylH2Ab1tm1GruH2Ab1tm1GruTgHLADQA1HLADQB170Myl0TgHLADQA1HLADQB170MylH2Ab1tm1Gru
• cyanosis_H2-Ab1<tm1Gru>/H2-Ab1<tm1Gru>,Tg(HLA-DQA1,HLA-DQB1)73Myl/0
  http://metadb.riken.jp/0001575NODCgH2Ab1tm1GruTgHLADQA1HLADQB173MylH2Ab1tm1GruH2Ab1tm1GruTgHLADQA1HLADQB173Myl0TgHLADQA1HLADQB173MylH2Ab1tm1Gru
• increased autoantibody level_H2-Ab1<tm1Gru>/H2-Ab1<tm1Gru>,Tg(HLA-DQA1,HLA-DQB1)73Myl/0
  http://metadb.riken.jp/0003725NODCgH2Ab1tm1GruTgHLADQA1HLADQB173MylH2Ab1tm1GruH2Ab1tm1GruTgHLADQA1HLADQB173Myl0TgHLADQA1HLADQB173MylH2Ab1tm1Gru
• abnormal breathing pattern_H2-Ab1<tm1Gru>/H2-Ab1<tm1Gru>,Tg(HLA-DQA1,HLA-DQB1)73Myl/0
  http://metadb.riken.jp/0001951NODCgH2Ab1tm1GruTgHLADQA1HLADQB173MylH2Ab1tm1GruH2Ab1tm1GruTgHLADQA1HLADQB173Myl0TgHLADQA1HLADQB173MylH2Ab1tm1Gru
• myocardial fiber degeneration_H2-Ab1<tm1Gru>/H2-Ab1<tm1Gru>,Tg(HLA-DQA1,HLA-DQB1)73Myl/0
  http://metadb.riken.jp/0004566NODCgH2Ab1tm1GruTgHLADQA1HLADQB173MylH2Ab1tm1GruH2Ab1tm1GruTgHLADQA1HLADQB173Myl0TgHLADQA1HLADQB173MylH2Ab1tm1Gru
• myocarditis_H2-Ab1<tm1Gru>/H2-Ab1<tm1Gru>,Tg(HLA-DQA1,HLA-DQB1)70Myl/0
  http://metadb.riken.jp/0001856NODCgH2Ab1tm1GruTgHLADQA1HLADQB170MylH2Ab1tm1GruH2Ab1tm1GruTgHLADQA1HLADQB170Myl0TgHLADQA1HLADQB170MylH2Ab1tm1Gru
• lethargy_H2-Ab1<tm1Gru>/H2-Ab1<tm1Gru>,Tg(HLA-DQA1,HLA-DQB1)73Myl/0
  http://metadb.riken.jp/0005202NODCgH2Ab1tm1GruTgHLADQA1HLADQB173MylH2Ab1tm1GruH2Ab1tm1GruTgHLADQA1HLADQB173Myl0TgHLADQA1HLADQB173MylH2Ab1tm1Gru
• premature death_H2-Ab1<tm1Gru>/H2-Ab1<tm1Gru>,Tg(HLA-DQA1,HLA-DQB1)73Myl/0
  http://metadb.riken.jp/0002083NODCgH2Ab1tm1GruTgHLADQA1HLADQB173MylH2Ab1tm1GruH2Ab1tm1GruTgHLADQA1HLADQB173Myl0TgHLADQA1HLADQB173MylH2Ab1tm1Gru
• increased autoantibody level_H2-Ab1<tm1Gru>/H2-Ab1<tm1Gru>,Tg(HLA-DQA1,HLA-DQB1)70Myl/0
  http://metadb.riken.jp/0003725NODCgH2Ab1tm1GruTgHLADQA1HLADQB170MylH2Ab1tm1GruH2Ab1tm1GruTgHLADQA1HLADQB170Myl0TgHLADQA1HLADQB170MylH2Ab1tm1Gru
• edema_H2-Ab1<tm1Gru>/H2-Ab1<tm1Gru>,Tg(HLA-DQA1,HLA-DQB1)73Myl/0
  http://metadb.riken.jp/0001785NODCgH2Ab1tm1GruTgHLADQA1HLADQB173MylH2Ab1tm1GruH2Ab1tm1GruTgHLADQA1HLADQB173Myl0TgHLADQA1HLADQB173MylH2Ab1tm1Gru
• myocarditis_H2-Ab1<tm1Gru>/H2-Ab1<tm1Gru>,Tg(HLA-DQA1,HLA-DQB1)73Myl/0
  http://metadb.riken.jp/0001856NODCgH2Ab1tm1GruTgHLADQA1HLADQB173MylH2Ab1tm1GruH2Ab1tm1GruTgHLADQA1HLADQB173Myl0TgHLADQA1HLADQB173MylH2Ab1tm1Gru
• abnormal myocardial fiber morphology_H2-Ab1<tm1Gru>/H2-Ab1<tm1Gru>,Tg(HLA-DQA1,HLA-DQB1)73Myl/0
  http://metadb.riken.jp/0000278NODCgH2Ab1tm1GruTgHLADQA1HLADQB173MylH2Ab1tm1GruH2Ab1tm1GruTgHLADQA1HLADQB173Myl0TgHLADQA1HLADQB173MylH2Ab1tm1Gru
• abnormal response to transplant_H2-Ab1<tm1Gru>/H2-Ab1<tm1Gru>,Rag1<tm1Mom>/Rag1<tm1Mom>,Tg(HLA-DQA1,HLA-DQB1)73Myl/0
  http://metadb.riken.jp/0005671NODCgRag1tm1MomH2Ab1tm1GruTgHLADQA1HLADQB173MylH2Ab1tm1GruH2Ab1tm1GruRag1tm1MomRag1tm1MomTgHLADQA1HLADQB173Myl0TgHLADQA1HLADQB173MylH2Ab1tm1GruRag1tm1Mom
• congestive heart failure_H2-Ab1<tm1Gru>/H2-Ab1<tm1Gru>,Tg(HLA-DQA1,HLA-DQB1)73Myl/0
  http://metadb.riken.jp/0006138NODCgH2Ab1tm1GruTgHLADQA1HLADQB173MylH2Ab1tm1GruH2Ab1tm1GruTgHLADQA1HLADQB173Myl0TgHLADQA1HLADQB173MylH2Ab1tm1Gru
• enlarged liver_H2-Ab1<tm1Gru>/H2-Ab1<tm1Gru>,Tg(HLA-DQA1,HLA-DQB1)73Myl/0
  http://metadb.riken.jp/0000599NODCgH2Ab1tm1GruTgHLADQA1HLADQB173MylH2Ab1tm1GruH2Ab1tm1GruTgHLADQA1HLADQB173Myl0TgHLADQA1HLADQB173MylH2Ab1tm1Gru
• liver hemorrhage_H2-Ab1<tm1Gru>/H2-Ab1<tm1Gru>,Tg(HLA-DQA1,HLA-DQB1)73Myl/0
  http://metadb.riken.jp/0003888NODCgH2Ab1tm1GruTgHLADQA1HLADQB173MylH2Ab1tm1GruH2Ab1tm1GruTgHLADQA1HLADQB173Myl0TgHLADQA1HLADQB173MylH2Ab1tm1Gru
• abnormal atrial thrombosis_H2-Ab1<tm1Gru>/H2-Ab1<tm1Gru>,Tg(HLA-DQA1,HLA-DQB1)73Myl/0
  http://metadb.riken.jp/0001855NODCgH2Ab1tm1GruTgHLADQA1HLADQB173MylH2Ab1tm1GruH2Ab1tm1GruTgHLADQA1HLADQB173Myl0TgHLADQA1HLADQB173MylH2Ab1tm1Gru
• salivary gland inflammation_H2-Ab1<tm1Gru>/H2-Ab1<tm1Gru>,Tg(HLA-DQA1,HLA-DQB1)73Myl/0
  http://metadb.riken.jp/0001870NODCgH2Ab1tm1GruTgHLADQA1HLADQB173MylH2Ab1tm1GruH2Ab1tm1GruTgHLADQA1HLADQB173Myl0TgHLADQA1HLADQB173MylH2Ab1tm1Gru
• myocardial necrosis_H2-Ab1<tm1Gru>/H2-Ab1<tm1Gru>,Tg(HLA-DQA1,HLA-DQB1)73Myl/0
  http://metadb.riken.jp/0006085NODCgH2Ab1tm1GruTgHLADQA1HLADQB173MylH2Ab1tm1GruH2Ab1tm1GruTgHLADQA1HLADQB173Myl0TgHLADQA1HLADQB173MylH2Ab1tm1Gru
• heart inflammation_H2-Ab1<tm1Gru>/H2-Ab1<tm1Gru>,Tg(HLA-DQA1,HLA-DQB1)70Myl/0
  http://metadb.riken.jp/0001853NODCgH2Ab1tm1GruTgHLADQA1HLADQB170MylH2Ab1tm1GruH2Ab1tm1GruTgHLADQA1HLADQB170Myl0TgHLADQA1HLADQB170MylH2Ab1tm1Gru
• salivary gland inflammation_H2-Ab1<tm1Gru>/H2-Ab1<tm1Gru>,Tg(HLA-DQA1,HLA-DQB1)70Myl/0
  http://metadb.riken.jp/0001870NODCgH2Ab1tm1GruTgHLADQA1HLADQB170MylH2Ab1tm1GruH2Ab1tm1GruTgHLADQA1HLADQB170Myl0TgHLADQA1HLADQB170MylH2Ab1tm1Gru
• abnormal liver morphology_H2-Ab1<tm1Gru>/H2-Ab1<tm1Gru>,Tg(HLA-DQA1,HLA-DQB1)73Myl/0
  http://metadb.riken.jp/0000598NODCgH2Ab1tm1GruTgHLADQA1HLADQB173MylH2Ab1tm1GruH2Ab1tm1GruTgHLADQA1HLADQB173Myl0TgHLADQA1HLADQB173MylH2Ab1tm1Gru

class

http://purl.org/net/cito/citesAsAuthority

• Tg(HLA-DQA1,HLA-DQB1)73Myl
  http://metadb.riken.jp/db/mgi_rdf/MGI:3687023
• Tg(HLA-DQA1,HLA-DQB1)70Myl
  http://metadb.riken.jp/db/mgi_rdf/MGI:3687022