Olga. Klezovitch, et.al., Loss of cell polarity causes severe brain dysplasia in Lgl1 knockout mice., Genes & development, 2004, 18

http://rdf.ncbi.nlm.nih.gov/pubmed/15037549

Olga. Klezovitch, et.al., Loss of cell polarity causes severe brain dysplasia in Lgl1 knockout mice., Genes & development, 2004, 18

pubmed

allele

http://purl.org/net/cito/citesAsAuthority

• Llgl1<tm1.1Vv>
  http://metadb.riken.jp/db/mgi_rdf/MGI:3039269
• Llgl1<tm1Vv>
  http://metadb.riken.jp/db/mgi_rdf/MGI:3039268

class

http://purl.org/net/cito/citesAsAuthority

• Llgl1<tm1.1Vv>
  http://metadb.riken.jp/db/mgi_rdf/MGI:3039269
• Llgl1<tm1Vv>
  http://metadb.riken.jp/db/mgi_rdf/MGI:3039268

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• abnormal neuron differentiation_Llgl1<tm1.1Vv>/Llgl1<tm1.1Vv>
  http://metadb.riken.jp/0009937NSLlgl1tm11VvLlgl1tm11VvLlgl1tm11Vv
• abnormal neuronal precursor proliferation_Llgl1<tm1.1Vv>/Llgl1<tm1.1Vv>
  http://metadb.riken.jp/0004948NSLlgl1tm11VvLlgl1tm11VvLlgl1tm11Vv
• neonatal lethality, complete penetrance_Llgl1<tm1.1Vv>/Llgl1<tm1.1Vv>
  http://metadb.riken.jp/0011087NSLlgl1tm11VvLlgl1tm11VvLlgl1tm11Vv
• intraventricular hemorrhage_Llgl1<tm1Vv>/Llgl1<tm1Vv>,Meox2<tm1(cre)Sor>/Meox2<+>
  http://metadb.riken.jp/0001917I129S4SvJaeSorC57BL6JLlgl1tm1VvLlgl1tm1VvMeox2tm1creSorMeox2Meox2tm1creSorLlgl1tm1VvMeox2
• domed cranium_Llgl1<tm1.1Vv>/Llgl1<tm1.1Vv>
  http://metadb.riken.jp/0000440NSLlgl1tm11VvLlgl1tm11VvLlgl1tm11Vv
• abnormal neuron differentiation_Llgl1<tm1Vv>/Llgl1<tm1Vv>,Meox2<tm1(cre)Sor>/Meox2<+>
  http://metadb.riken.jp/0009937I129S4SvJaeSorC57BL6JLlgl1tm1VvLlgl1tm1VvMeox2tm1creSorMeox2Meox2tm1creSorLlgl1tm1VvMeox2
• abnormal embryonic neuroepithelial layer differentiation_Llgl1<tm1.1Vv>/Llgl1<tm1.1Vv>
  http://metadb.riken.jp/0000786NSLlgl1tm11VvLlgl1tm11VvLlgl1tm11Vv
• abnormal brain vasculature morphology_Llgl1<tm1Vv>/Llgl1<tm1Vv>,Meox2<tm1(cre)Sor>/Meox2<+>
  http://metadb.riken.jp/0004950I129S4SvJaeSorC57BL6JLlgl1tm1VvLlgl1tm1VvMeox2tm1creSorMeox2Meox2tm1creSorLlgl1tm1VvMeox2
• dilated brain ventricles_Llgl1<tm1.1Vv>/Llgl1<tm1.1Vv>
  http://metadb.riken.jp/0012676NSLlgl1tm11VvLlgl1tm11VvLlgl1tm11Vv
• abnormal striatum morphology_Llgl1<tm1.1Vv>/Llgl1<tm1.1Vv>
  http://metadb.riken.jp/0004077NSLlgl1tm11VvLlgl1tm11VvLlgl1tm11Vv
• neonatal lethality, complete penetrance_Llgl1<tm1Vv>/Llgl1<tm1Vv>,Meox2<tm1(cre)Sor>/Meox2<+>
  http://metadb.riken.jp/0011087I129S4SvJaeSorC57BL6JLlgl1tm1VvLlgl1tm1VvMeox2tm1creSorMeox2Meox2tm1creSorLlgl1tm1VvMeox2
• increased neuronal precursor cell number_Llgl1<tm1Vv>/Llgl1<tm1Vv>,Meox2<tm1(cre)Sor>/Meox2<+>
  http://metadb.riken.jp/0004980I129S4SvJaeSorC57BL6JLlgl1tm1VvLlgl1tm1VvMeox2tm1creSorMeox2Meox2tm1creSorLlgl1tm1VvMeox2
• abnormal embryonic neuroepithelium morphology_Llgl1<tm1Vv>/Llgl1<tm1Vv>,Meox2<tm1(cre)Sor>/Meox2<+>
  http://metadb.riken.jp/0004261I129S4SvJaeSorC57BL6JLlgl1tm1VvLlgl1tm1VvMeox2tm1creSorMeox2Meox2tm1creSorLlgl1tm1VvMeox2
• domed cranium_Llgl1<tm1Vv>/Llgl1<tm1Vv>,Meox2<tm1(cre)Sor>/Meox2<+>
  http://metadb.riken.jp/0000440I129S4SvJaeSorC57BL6JLlgl1tm1VvLlgl1tm1VvMeox2tm1creSorMeox2Meox2tm1creSorLlgl1tm1VvMeox2
• dilated brain ventricles_Llgl1<tm1Vv>/Llgl1<tm1Vv>,Meox2<tm1(cre)Sor>/Meox2<+>
  http://metadb.riken.jp/0012676I129S4SvJaeSorC57BL6JLlgl1tm1VvLlgl1tm1VvMeox2tm1creSorMeox2Meox2tm1creSorLlgl1tm1VvMeox2
• abnormal embryonic neuroepithelium morphology_Llgl1<tm1.1Vv>/Llgl1<tm1.1Vv>
  http://metadb.riken.jp/0004261NSLlgl1tm11VvLlgl1tm11VvLlgl1tm11Vv
• decreased neuron number_Llgl1<tm1.1Vv>/Llgl1<tm1.1Vv>
  http://metadb.riken.jp/0008948NSLlgl1tm11VvLlgl1tm11VvLlgl1tm11Vv
• dilated lateral ventricles_Llgl1<tm1.1Vv>/Llgl1<tm1.1Vv>
  http://metadb.riken.jp/0000825NSLlgl1tm11VvLlgl1tm11VvLlgl1tm11Vv
• hydroencephaly_Llgl1<tm1.1Vv>/Llgl1<tm1.1Vv>
  http://metadb.riken.jp/0001891NSLlgl1tm11VvLlgl1tm11VvLlgl1tm11Vv
• abnormal brain vasculature morphology_Llgl1<tm1.1Vv>/Llgl1<tm1.1Vv>
  http://metadb.riken.jp/0004950NSLlgl1tm11VvLlgl1tm11VvLlgl1tm11Vv
• hydroencephaly_Llgl1<tm1Vv>/Llgl1<tm1Vv>,Meox2<tm1(cre)Sor>/Meox2<+>
  http://metadb.riken.jp/0001891I129S4SvJaeSorC57BL6JLlgl1tm1VvLlgl1tm1VvMeox2tm1creSorMeox2Meox2tm1creSorLlgl1tm1VvMeox2
• abnormal striatum morphology_Llgl1<tm1Vv>/Llgl1<tm1Vv>,Meox2<tm1(cre)Sor>/Meox2<+>
  http://metadb.riken.jp/0004077I129S4SvJaeSorC57BL6JLlgl1tm1VvLlgl1tm1VvMeox2tm1creSorMeox2Meox2tm1creSorLlgl1tm1VvMeox2
• abnormal neuronal precursor proliferation_Llgl1<tm1Vv>/Llgl1<tm1Vv>,Meox2<tm1(cre)Sor>/Meox2<+>
  http://metadb.riken.jp/0004948I129S4SvJaeSorC57BL6JLlgl1tm1VvLlgl1tm1VvMeox2tm1creSorMeox2Meox2tm1creSorLlgl1tm1VvMeox2
• decreased neuron number_Llgl1<tm1Vv>/Llgl1<tm1Vv>,Meox2<tm1(cre)Sor>/Meox2<+>
  http://metadb.riken.jp/0008948I129S4SvJaeSorC57BL6JLlgl1tm1VvLlgl1tm1VvMeox2tm1creSorMeox2Meox2tm1creSorLlgl1tm1VvMeox2
• abnormal embryonic neuroepithelial layer differentiation_Llgl1<tm1Vv>/Llgl1<tm1Vv>,Meox2<tm1(cre)Sor>/Meox2<+>
  http://metadb.riken.jp/0000786I129S4SvJaeSorC57BL6JLlgl1tm1VvLlgl1tm1VvMeox2tm1creSorMeox2Meox2tm1creSorLlgl1tm1VvMeox2
• abnormal cerebral cortex morphology_Llgl1<tm1Vv>/Llgl1<tm1Vv>,Meox2<tm1(cre)Sor>/Meox2<+>
  http://metadb.riken.jp/0000788I129S4SvJaeSorC57BL6JLlgl1tm1VvLlgl1tm1VvMeox2tm1creSorMeox2Meox2tm1creSorLlgl1tm1VvMeox2
• dilated lateral ventricles_Llgl1<tm1Vv>/Llgl1<tm1Vv>,Meox2<tm1(cre)Sor>/Meox2<+>
  http://metadb.riken.jp/0000825I129S4SvJaeSorC57BL6JLlgl1tm1VvLlgl1tm1VvMeox2tm1creSorMeox2Meox2tm1creSorLlgl1tm1VvMeox2
• abnormal cerebral cortex morphology_Llgl1<tm1.1Vv>/Llgl1<tm1.1Vv>
  http://metadb.riken.jp/0000788NSLlgl1tm11VvLlgl1tm11VvLlgl1tm11Vv
• increased neuronal precursor cell number_Llgl1<tm1.1Vv>/Llgl1<tm1.1Vv>
  http://metadb.riken.jp/0004980NSLlgl1tm11VvLlgl1tm11VvLlgl1tm11Vv
• intraventricular hemorrhage_Llgl1<tm1.1Vv>/Llgl1<tm1.1Vv>
  http://metadb.riken.jp/0001917NSLlgl1tm11VvLlgl1tm11VvLlgl1tm11Vv

トランスクリプトームデータ

http://rdf.ncbi.nlm.nih.gov/pubmed/

• CD06390
  http://metadb.riken.jp/db/BrainTx/TranscriptomeData/CD06390
• CD00544
  http://metadb.riken.jp/db/BrainTx/TranscriptomeData/CD00544