Terry P. Maddatu, et.al., Transgenic rescue of neurogenic atrophy in the nmd mouse reveals a role for Ighmbp2 in dilated cardiomyopathy., Human molecular genetics, 2004, 13

http://rdf.ncbi.nlm.nih.gov/pubmed/15069027

Terry P. Maddatu, et.al., Transgenic rescue of neurogenic atrophy in the nmd mouse reveals a role for Ighmbp2 in dilated cardiomyopathy., Human molecular genetics, 2004, 13

pubmed

allele

http://purl.org/net/cito/citesAsAuthority

• Tg(Eno2-Ighmbp2)17Cx
  http://metadb.riken.jp/db/mgi_rdf/MGI:3765055
• Tg(Eno2-Ighmbp2)90Cx
  http://metadb.riken.jp/db/mgi_rdf/MGI:3784996

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• decreased systemic arterial systolic blood pressure_Ighmbp2<nmd-2J>/Ighmbp2<nmd-2J>
  http://metadb.riken.jp/0006264B6BKSIghmbp2nmd2JJIghmbp2nmd2JIghmbp2nmd2JIghmbp2nmd2J
• abnormal impulse conducting system conduction_Ighmbp2<nmd-2J>/Ighmbp2<nmd-2J>,Tg(Eno2-Ighmbp2)17Cx/?
  http://metadb.riken.jp/0003137IC57BL6JC57BLKSJIghmbp2nmd2JIghmbp2nmd2JTgEno2Ighmbp217CxTgEno2Ighmbp217CxIghmbp2nmd2J
• prolonged QRS complex duration_Ighmbp2<nmd-2J>/Ighmbp2<nmd-2J>,Tg(Eno2-Ighmbp2)17Cx/?
  http://metadb.riken.jp/0010392IC57BL6JC57BLKSJIghmbp2nmd2JIghmbp2nmd2JTgEno2Ighmbp217CxTgEno2Ighmbp217CxIghmbp2nmd2J
• weight loss_Ighmbp2<nmd-2J>/Ighmbp2<nmd-2J>
  http://metadb.riken.jp/0001263B6BKSIghmbp2nmd2JJIghmbp2nmd2JIghmbp2nmd2JIghmbp2nmd2J
• thin ventricular wall_Ighmbp2<nmd-2J>/Ighmbp2<nmd-2J>
  http://metadb.riken.jp/0000280B6BKSIghmbp2nmd2JJIghmbp2nmd2JIghmbp2nmd2JIghmbp2nmd2J
• dilated cardiomyopathy_Ighmbp2<nmd-2J>/Ighmbp2<nmd-2J>
  http://metadb.riken.jp/0002795B6BKSIghmbp2nmd2JJIghmbp2nmd2JIghmbp2nmd2JIghmbp2nmd2J
• increased variability of skeletal muscle fiber size_Ighmbp2<nmd-2J>/Ighmbp2<nmd-2J>
  http://metadb.riken.jp/0009403B6BKSIghmbp2nmd2JJIghmbp2nmd2JIghmbp2nmd2JIghmbp2nmd2J
• premature death_Ighmbp2<nmd-2J>/Ighmbp2<nmd-2J>,Tg(Eno2-Ighmbp2)17Cx/?
  http://metadb.riken.jp/0002083IC57BL6JC57BLKSJIghmbp2nmd2JIghmbp2nmd2JTgEno2Ighmbp217CxTgEno2Ighmbp217CxIghmbp2nmd2J
• abnormal heart valve morphology_Ighmbp2<nmd-2J>/Ighmbp2<nmd-2J>
  http://metadb.riken.jp/0000285B6BKSIghmbp2nmd2JJIghmbp2nmd2JIghmbp2nmd2JIghmbp2nmd2J
• premature death_Ighmbp2<nmd-2J>/Ighmbp2<nmd-2J>
  http://metadb.riken.jp/0002083B6BKSIghmbp2nmd2JJIghmbp2nmd2JIghmbp2nmd2JIghmbp2nmd2J
• decreased pulmonary respiratory rate_Ighmbp2<nmd-2J>/Ighmbp2<nmd-2J>,Tg(Eno2-Ighmbp2)90Cx/?
  http://metadb.riken.jp/0005574IC57BL6JC57BLKSJIghmbp2nmd2JIghmbp2nmd2JTgEno2Ighmbp290CxIghmbp2nmd2JTgEno2Ighmbp290Cx
• skeletal muscle interstitial fibrosis_Ighmbp2<nmd-2J>/Ighmbp2<nmd-2J>
  http://metadb.riken.jp/0003851B6BKSIghmbp2nmd2JJIghmbp2nmd2JIghmbp2nmd2JIghmbp2nmd2J
• decreased heart rate_Ighmbp2<nmd-2J>/Ighmbp2<nmd-2J>
  http://metadb.riken.jp/0005333B6BKSIghmbp2nmd2JJIghmbp2nmd2JIghmbp2nmd2JIghmbp2nmd2J
• dilated cardiomyopathy_Ighmbp2<nmd-2J>/Ighmbp2<nmd-2J>,Tg(Eno2-Ighmbp2)90Cx/?
  http://metadb.riken.jp/0002795IC57BL6JC57BLKSJIghmbp2nmd2JIghmbp2nmd2JTgEno2Ighmbp290CxIghmbp2nmd2JTgEno2Ighmbp290Cx
• prolonged QRS complex duration_Ighmbp2<nmd-2J>/Ighmbp2<nmd-2J>,Mnm<C>/Mnm<C>
  http://metadb.riken.jp/0010392IC57BL6JC57BLKSJCASTEiDBAJIghmbp2nmd2JIghmbp2nmd2JMnmCMnmCIghmbp2nmd2JMnmC
• increased circulating creatine kinase level_Ighmbp2<nmd-2J>/Ighmbp2<nmd-2J>
  http://metadb.riken.jp/0010090B6BKSIghmbp2nmd2JJIghmbp2nmd2JIghmbp2nmd2JIghmbp2nmd2J
• premature death_Ighmbp2<nmd-2J>/Ighmbp2<nmd-2J>,Mnm<C>/Mnm<C>
  http://metadb.riken.jp/0002083IC57BL6JC57BLKSJCASTEiDBAJIghmbp2nmd2JIghmbp2nmd2JMnmCMnmCIghmbp2nmd2JMnmC
• muscle degeneration_Ighmbp2<nmd-2J>/Ighmbp2<nmd-2J>
  http://metadb.riken.jp/0000749B6BKSIghmbp2nmd2JJIghmbp2nmd2JIghmbp2nmd2JIghmbp2nmd2J
• muscle degeneration_Ighmbp2<nmd-2J>/Ighmbp2<nmd-2J>,Tg(Eno2-Ighmbp2)17Cx/?
  http://metadb.riken.jp/0000749IC57BL6JC57BLKSJIghmbp2nmd2JIghmbp2nmd2JTgEno2Ighmbp217CxTgEno2Ighmbp217CxIghmbp2nmd2J
• abnormal cardiovascular system physiology_Ighmbp2<nmd-2J>/Ighmbp2<nmd-2J>,Tg(Eno2-Ighmbp2)17Cx/?
  http://metadb.riken.jp/0001544IC57BL6JC57BLKSJIghmbp2nmd2JIghmbp2nmd2JTgEno2Ighmbp217CxTgEno2Ighmbp217CxIghmbp2nmd2J
• pulmonary edema_Ighmbp2<nmd-2J>/Ighmbp2<nmd-2J>,Tg(Eno2-Ighmbp2)90Cx/?
  http://metadb.riken.jp/0003828IC57BL6JC57BLKSJIghmbp2nmd2JIghmbp2nmd2JTgEno2Ighmbp290CxIghmbp2nmd2JTgEno2Ighmbp290Cx
• abnormal heart ventricle morphology_Ighmbp2<nmd-2J>/Ighmbp2<nmd-2J>
  http://metadb.riken.jp/0005294B6BKSIghmbp2nmd2JJIghmbp2nmd2JIghmbp2nmd2JIghmbp2nmd2J
• pleural effusion_Ighmbp2<nmd-2J>/Ighmbp2<nmd-2J>,Tg(Eno2-Ighmbp2)17Cx/?
  http://metadb.riken.jp/0010334IC57BL6JC57BLKSJIghmbp2nmd2JIghmbp2nmd2JTgEno2Ighmbp217CxTgEno2Ighmbp217CxIghmbp2nmd2J
• prolonged P wave_Ighmbp2<nmd-2J>/Ighmbp2<nmd-2J>,Mnm<C>/Mnm<C>
  http://metadb.riken.jp/0004071IC57BL6JC57BLKSJCASTEiDBAJIghmbp2nmd2JIghmbp2nmd2JMnmCMnmCIghmbp2nmd2JMnmC
• increased circulating creatine kinase level_Ighmbp2<nmd-2J>/Ighmbp2<nmd-2J>,Tg(Eno2-Ighmbp2)17Cx/?
  http://metadb.riken.jp/0010090IC57BL6JC57BLKSJIghmbp2nmd2JIghmbp2nmd2JTgEno2Ighmbp217CxTgEno2Ighmbp217CxIghmbp2nmd2J
• abnormal heart morphology_Ighmbp2<nmd-2J>/Ighmbp2<nmd-2J>
  http://metadb.riken.jp/0000266B6BKSIghmbp2nmd2JJIghmbp2nmd2JIghmbp2nmd2JIghmbp2nmd2J
• abnormal impulse conducting system conduction_Ighmbp2<nmd-2J>/Ighmbp2<nmd-2J>,Mnm<C>/Mnm<C>
  http://metadb.riken.jp/0003137IC57BL6JC57BLKSJCASTEiDBAJIghmbp2nmd2JIghmbp2nmd2JMnmCMnmCIghmbp2nmd2JMnmC
• centrally nucleated skeletal muscle fibers_Ighmbp2<nmd-2J>/Ighmbp2<nmd-2J>
  http://metadb.riken.jp/0009404B6BKSIghmbp2nmd2JJIghmbp2nmd2JIghmbp2nmd2JIghmbp2nmd2J
• muscle degeneration_Ighmbp2<nmd-2J>/Ighmbp2<nmd-2J>,Mnm<C>/Mnm<C>
  http://metadb.riken.jp/0000749IC57BL6JC57BLKSJCASTEiDBAJIghmbp2nmd2JIghmbp2nmd2JMnmCMnmCIghmbp2nmd2JMnmC
• abnormal cardiovascular system physiology_Ighmbp2<nmd-2J>/Ighmbp2<nmd-2J>
  http://metadb.riken.jp/0001544B6BKSIghmbp2nmd2JJIghmbp2nmd2JIghmbp2nmd2JIghmbp2nmd2J
• decreased pulmonary respiratory rate_Ighmbp2<nmd-2J>/Ighmbp2<nmd-2J>
  http://metadb.riken.jp/0005574B6BKSIghmbp2nmd2JJIghmbp2nmd2JIghmbp2nmd2JIghmbp2nmd2J
• dilated cardiomyopathy_Ighmbp2<nmd-2J>/Ighmbp2<nmd-2J>,Tg(Eno2-Ighmbp2)17Cx/?
  http://metadb.riken.jp/0002795IC57BL6JC57BLKSJIghmbp2nmd2JIghmbp2nmd2JTgEno2Ighmbp217CxTgEno2Ighmbp217CxIghmbp2nmd2J
• increased circulating creatine kinase level_Ighmbp2<nmd-2J>/Ighmbp2<nmd-2J>,Mnm<C>/Mnm<C>
  http://metadb.riken.jp/0010090IC57BL6JC57BLKSJCASTEiDBAJIghmbp2nmd2JIghmbp2nmd2JMnmCMnmCIghmbp2nmd2JMnmC
• dilated cardiomyopathy_Ighmbp2<nmd-2J>/Ighmbp2<nmd-2J>,Mnm<C>/Mnm<C>
  http://metadb.riken.jp/0002795IC57BL6JC57BLKSJCASTEiDBAJIghmbp2nmd2JIghmbp2nmd2JMnmCMnmCIghmbp2nmd2JMnmC
• abnormal myocardial fiber morphology_Ighmbp2<nmd-2J>/Ighmbp2<nmd-2J>
  http://metadb.riken.jp/0000278B6BKSIghmbp2nmd2JJIghmbp2nmd2JIghmbp2nmd2JIghmbp2nmd2J
• decreased grip strength_Ighmbp2<nmd-2J>/Ighmbp2<nmd-2J>,Mnm<C>/Mnm<C>
  http://metadb.riken.jp/0010053IC57BL6JC57BLKSJCASTEiDBAJIghmbp2nmd2JIghmbp2nmd2JMnmCMnmCIghmbp2nmd2JMnmC
• decreased grip strength_Ighmbp2<nmd-2J>/Ighmbp2<nmd-2J>
  http://metadb.riken.jp/0010053B6BKSIghmbp2nmd2JJIghmbp2nmd2JIghmbp2nmd2JIghmbp2nmd2J
• abnormal cardiovascular system physiology_Ighmbp2<nmd-2J>/Ighmbp2<nmd-2J>,Mnm<C>/Mnm<C>
  http://metadb.riken.jp/0001544IC57BL6JC57BLKSJCASTEiDBAJIghmbp2nmd2JIghmbp2nmd2JMnmCMnmCIghmbp2nmd2JMnmC
• cardiac interstitial fibrosis_Ighmbp2<nmd-2J>/Ighmbp2<nmd-2J>
  http://metadb.riken.jp/0005608B6BKSIghmbp2nmd2JJIghmbp2nmd2JIghmbp2nmd2JIghmbp2nmd2J
• prolonged PR interval_Ighmbp2<nmd-2J>/Ighmbp2<nmd-2J>
  http://metadb.riken.jp/0003896B6BKSIghmbp2nmd2JJIghmbp2nmd2JIghmbp2nmd2JIghmbp2nmd2J
• abnormal intercalated disc morphology_Ighmbp2<nmd-2J>/Ighmbp2<nmd-2J>
  http://metadb.riken.jp/0006267B6BKSIghmbp2nmd2JJIghmbp2nmd2JIghmbp2nmd2JIghmbp2nmd2J
• increased heart rate variability_Ighmbp2<nmd-2J>/Ighmbp2<nmd-2J>
  http://metadb.riken.jp/0003928B6BKSIghmbp2nmd2JJIghmbp2nmd2JIghmbp2nmd2JIghmbp2nmd2J
• dilated heart atrium_Ighmbp2<nmd-2J>/Ighmbp2<nmd-2J>
  http://metadb.riken.jp/0003140B6BKSIghmbp2nmd2JJIghmbp2nmd2JIghmbp2nmd2JIghmbp2nmd2J
• prolonged P wave_Ighmbp2<nmd-2J>/Ighmbp2<nmd-2J>
  http://metadb.riken.jp/0004071B6BKSIghmbp2nmd2JJIghmbp2nmd2JIghmbp2nmd2JIghmbp2nmd2J
• motor neuron degeneration_Ighmbp2<nmd-2J>/Ighmbp2<nmd-2J>,Mnm<C>/Mnm<C>
  http://metadb.riken.jp/0000938IC57BL6JC57BLKSJCASTEiDBAJIghmbp2nmd2JIghmbp2nmd2JMnmCMnmCIghmbp2nmd2JMnmC
• prolonged PR interval_Ighmbp2<nmd-2J>/Ighmbp2<nmd-2J>,Mnm<C>/Mnm<C>
  http://metadb.riken.jp/0003896IC57BL6JC57BLKSJCASTEiDBAJIghmbp2nmd2JIghmbp2nmd2JMnmCMnmCIghmbp2nmd2JMnmC
• decreased pulmonary respiratory rate_Ighmbp2<nmd-2J>/Ighmbp2<nmd-2J>,Tg(Eno2-Ighmbp2)17Cx/?
  http://metadb.riken.jp/0005574IC57BL6JC57BLKSJIghmbp2nmd2JIghmbp2nmd2JTgEno2Ighmbp217CxTgEno2Ighmbp217CxIghmbp2nmd2J
• weight loss_Ighmbp2<nmd-2J>/Ighmbp2<nmd-2J>,Tg(Eno2-Ighmbp2)90Cx/?
  http://metadb.riken.jp/0001263IC57BL6JC57BLKSJIghmbp2nmd2JIghmbp2nmd2JTgEno2Ighmbp290CxIghmbp2nmd2JTgEno2Ighmbp290Cx
• abnormal QRS complex_Ighmbp2<nmd-2J>/Ighmbp2<nmd-2J>
  http://metadb.riken.jp/0003898B6BKSIghmbp2nmd2JJIghmbp2nmd2JIghmbp2nmd2JIghmbp2nmd2J
• abnormal PR interval_Ighmbp2<nmd-2J>/Ighmbp2<nmd-2J>,Tg(Eno2-Ighmbp2)90Cx/?
  http://metadb.riken.jp/0003901IC57BL6JC57BLKSJIghmbp2nmd2JIghmbp2nmd2JTgEno2Ighmbp290CxIghmbp2nmd2JTgEno2Ighmbp290Cx
• muscle degeneration_Ighmbp2<nmd-2J>/Ighmbp2<nmd-2J>,Tg(Eno2-Ighmbp2)90Cx/?
  http://metadb.riken.jp/0000749IC57BL6JC57BLKSJIghmbp2nmd2JIghmbp2nmd2JTgEno2Ighmbp290CxIghmbp2nmd2JTgEno2Ighmbp290Cx
• myocardial fiber degeneration_Ighmbp2<nmd-2J>/Ighmbp2<nmd-2J>
  http://metadb.riken.jp/0004566B6BKSIghmbp2nmd2JJIghmbp2nmd2JIghmbp2nmd2JIghmbp2nmd2J
• weight loss_Ighmbp2<nmd-2J>/Ighmbp2<nmd-2J>,Mnm<C>/Mnm<C>
  http://metadb.riken.jp/0001263IC57BL6JC57BLKSJCASTEiDBAJIghmbp2nmd2JIghmbp2nmd2JMnmCMnmCIghmbp2nmd2JMnmC
• abnormal impulse conducting system conduction_Ighmbp2<nmd-2J>/Ighmbp2<nmd-2J>,Tg(Eno2-Ighmbp2)90Cx/?
  http://metadb.riken.jp/0003137IC57BL6JC57BLKSJIghmbp2nmd2JIghmbp2nmd2JTgEno2Ighmbp290CxIghmbp2nmd2JTgEno2Ighmbp290Cx
• skeletal muscle fiber atrophy_Ighmbp2<nmd-2J>/Ighmbp2<nmd-2J>
  http://metadb.riken.jp/0009413B6BKSIghmbp2nmd2JJIghmbp2nmd2JIghmbp2nmd2JIghmbp2nmd2J
• abnormal cardiovascular system physiology_Ighmbp2<nmd-2J>/Ighmbp2<nmd-2J>,Tg(Eno2-Ighmbp2)90Cx/?
  http://metadb.riken.jp/0001544IC57BL6JC57BLKSJIghmbp2nmd2JIghmbp2nmd2JTgEno2Ighmbp290CxIghmbp2nmd2JTgEno2Ighmbp290Cx
• prolonged P wave_Ighmbp2<nmd-2J>/Ighmbp2<nmd-2J>,Tg(Eno2-Ighmbp2)17Cx/?
  http://metadb.riken.jp/0004071IC57BL6JC57BLKSJIghmbp2nmd2JIghmbp2nmd2JTgEno2Ighmbp217CxTgEno2Ighmbp217CxIghmbp2nmd2J
• dilated heart ventricle_Ighmbp2<nmd-2J>/Ighmbp2<nmd-2J>
  http://metadb.riken.jp/0008022B6BKSIghmbp2nmd2JJIghmbp2nmd2JIghmbp2nmd2JIghmbp2nmd2J
• pleural effusion_Ighmbp2<nmd-2J>/Ighmbp2<nmd-2J>,Mnm<C>/Mnm<C>
  http://metadb.riken.jp/0010334IC57BL6JC57BLKSJCASTEiDBAJIghmbp2nmd2JIghmbp2nmd2JMnmCMnmCIghmbp2nmd2JMnmC
• myocardial necrosis_Ighmbp2<nmd-2J>/Ighmbp2<nmd-2J>
  http://metadb.riken.jp/0006085B6BKSIghmbp2nmd2JJIghmbp2nmd2JIghmbp2nmd2JIghmbp2nmd2J
• abnormal impulse conducting system conduction_Ighmbp2<nmd-2J>/Ighmbp2<nmd-2J>
  http://metadb.riken.jp/0003137B6BKSIghmbp2nmd2JJIghmbp2nmd2JIghmbp2nmd2JIghmbp2nmd2J
• pulmonary edema_Ighmbp2<nmd-2J>/Ighmbp2<nmd-2J>,Tg(Eno2-Ighmbp2)17Cx/?
  http://metadb.riken.jp/0003828IC57BL6JC57BLKSJIghmbp2nmd2JIghmbp2nmd2JTgEno2Ighmbp217CxTgEno2Ighmbp217CxIghmbp2nmd2J
• premature death_Ighmbp2<nmd-2J>/Ighmbp2<nmd-2J>,Tg(Eno2-Ighmbp2)90Cx/?
  http://metadb.riken.jp/0002083IC57BL6JC57BLKSJIghmbp2nmd2JIghmbp2nmd2JTgEno2Ighmbp290CxIghmbp2nmd2JTgEno2Ighmbp290Cx
• pulmonary edema_Ighmbp2<nmd-2J>/Ighmbp2<nmd-2J>
  http://metadb.riken.jp/0003828B6BKSIghmbp2nmd2JJIghmbp2nmd2JIghmbp2nmd2JIghmbp2nmd2J
• prolonged P wave_Ighmbp2<nmd-2J>/Ighmbp2<nmd-2J>,Tg(Eno2-Ighmbp2)90Cx/?
  http://metadb.riken.jp/0004071IC57BL6JC57BLKSJIghmbp2nmd2JIghmbp2nmd2JTgEno2Ighmbp290CxIghmbp2nmd2JTgEno2Ighmbp290Cx
• decreased pulmonary respiratory rate_Ighmbp2<nmd-2J>/Ighmbp2<nmd-2J>,Mnm<C>/Mnm<C>
  http://metadb.riken.jp/0005574IC57BL6JC57BLKSJCASTEiDBAJIghmbp2nmd2JIghmbp2nmd2JMnmCMnmCIghmbp2nmd2JMnmC
• pleural effusion_Ighmbp2<nmd-2J>/Ighmbp2<nmd-2J>
  http://metadb.riken.jp/0010334B6BKSIghmbp2nmd2JJIghmbp2nmd2JIghmbp2nmd2JIghmbp2nmd2J
• prolonged PR interval_Ighmbp2<nmd-2J>/Ighmbp2<nmd-2J>,Tg(Eno2-Ighmbp2)17Cx/?
  http://metadb.riken.jp/0003896IC57BL6JC57BLKSJIghmbp2nmd2JIghmbp2nmd2JTgEno2Ighmbp217CxTgEno2Ighmbp217CxIghmbp2nmd2J
• pulmonary edema_Ighmbp2<nmd-2J>/Ighmbp2<nmd-2J>,Mnm<C>/Mnm<C>
  http://metadb.riken.jp/0003828IC57BL6JC57BLKSJCASTEiDBAJIghmbp2nmd2JIghmbp2nmd2JMnmCMnmCIghmbp2nmd2JMnmC
• abnormal QRS complex_Ighmbp2<nmd-2J>/Ighmbp2<nmd-2J>,Tg(Eno2-Ighmbp2)90Cx/?
  http://metadb.riken.jp/0003898IC57BL6JC57BLKSJIghmbp2nmd2JIghmbp2nmd2JTgEno2Ighmbp290CxIghmbp2nmd2JTgEno2Ighmbp290Cx
• motor neuron degeneration_Ighmbp2<nmd-2J>/Ighmbp2<nmd-2J>
  http://metadb.riken.jp/0000938B6BKSIghmbp2nmd2JJIghmbp2nmd2JIghmbp2nmd2JIghmbp2nmd2J
• weight loss_Ighmbp2<nmd-2J>/Ighmbp2<nmd-2J>,Tg(Eno2-Ighmbp2)17Cx/?
  http://metadb.riken.jp/0001263IC57BL6JC57BLKSJIghmbp2nmd2JIghmbp2nmd2JTgEno2Ighmbp217CxTgEno2Ighmbp217CxIghmbp2nmd2J

class

http://purl.org/net/cito/citesAsAuthority

• Tg(Eno2-Ighmbp2)17Cx
  http://metadb.riken.jp/db/mgi_rdf/MGI:3765055
• Tg(Eno2-Ighmbp2)90Cx
  http://metadb.riken.jp/db/mgi_rdf/MGI:3784996