David A. Tuveson, et.al., Endogenous oncogenic K-ras(G12D) stimulates proliferation and widespread neoplastic and developmental defects., Cancer cell, 2004, 5

http://rdf.ncbi.nlm.nih.gov/pubmed/15093544

David A. Tuveson, et.al., Endogenous oncogenic K-ras(G12D) stimulates proliferation and widespread neoplastic and developmental defects., Cancer cell, 2004, 5

pubmed

allele

http://purl.org/net/cito/citesAsAuthority

• Kras<tm4.1Tyj>
  http://metadb.riken.jp/db/mgi_rdf/MGI:3044565

class

http://purl.org/net/cito/citesAsAuthority

• Kras<tm4.1Tyj>
  http://metadb.riken.jp/db/mgi_rdf/MGI:3044565

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• decreased embryo size_Kras<tm4.1Tyj>/Kras<+>
  http://metadb.riken.jp/0001698NSKrastm41TyjKrasKrasKrastm41Tyj
• submandibular gland hyperplasia_Kras<tm4Tyj>/Kras<+>,Tg(MMTV-cre)4Mam/0
  http://metadb.riken.jp/0009523I129S4SvJaeFVBKrastm4TyjKrasTgMMTVcre4Mam0TgMMTVcre4MamKrasKrastm4Tyj
• embryonic lethality during organogenesis, complete penetrance_Kras<tm4.1Tyj>/Kras<+>
  http://metadb.riken.jp/0011098NSKrastm41TyjKrasKrasKrastm41Tyj
• enlarged heart_Kras<tm4.1Tyj>/Kras<+>
  http://metadb.riken.jp/0000274NSKrastm41TyjKrasKrasKrastm41Tyj
• increased embryonic neuroepithelium apoptosis_Kras<tm4.1Tyj>/Kras<+>
  http://metadb.riken.jp/0012701NSKrastm41TyjKrasKrasKrastm41Tyj
• abnormal colon morphology_Kras<tm4Tyj>/Kras<+>,Tg(Fabp1-cre)1Jig/0
  http://metadb.riken.jp/0000495I129S4SvJaeFVBNKrastm4TyjKrasTgFabp1cre1Jig0TgFabp1cre1JigKrasKrastm4Tyj
• abnormal embryonic neuroepithelium morphology_Kras<tm4.1Tyj>/Kras<+>
  http://metadb.riken.jp/0004261NSKrastm41TyjKrasKrasKrastm41Tyj
• pallor_Kras<tm4.1Tyj>/Kras<+>
  http://metadb.riken.jp/0003717NSKrastm41TyjKrasKrasKrastm41Tyj
• abnormal brain development_Kras<tm4.1Tyj>/Kras<+>
  http://metadb.riken.jp/0000913NSKrastm41TyjKrasKrasKrastm41Tyj