Tadamichi. Akagi, et.al., Requirement of multiple basic helix-loop-helix genes for retinal neuronal subtype specification., The Journal of biological chemistry, 2004, 279

http://rdf.ncbi.nlm.nih.gov/pubmed/15105417

Tadamichi. Akagi, et.al., Requirement of multiple basic helix-loop-helix genes for retinal neuronal subtype specification., The Journal of biological chemistry, 2004, 279

pubmed

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• perinatal lethality, complete penetrance_Ascl1<tm1And>/Ascl1<tm1And>,Neurod4<tm1Kag>/Neurod4<tm1Kag>,Neurog2<tm1Fgu>/Neurog2<tm1Fgu>
  http://metadb.riken.jp/0011089I129SvC57BL6CBAICRAscl1tm1AndAscl1tm1AndNeurod4tm1KagNeurod4tm1KagNeurog2tm1FguNeurog2tm1FguNeurod4tm1KagAscl1tm1AndNeurog2tm1Fgu
• perinatal lethality, complete penetrance_Neurod4<tm1Kag>/Neurod4<tm1Kag>,Neurog2<tm1Fgu>/Neurog2<tm1Fgu>
  http://metadb.riken.jp/0011089I129S1Sv129X1SvJC57BL6CBAICRNeurod4tm1KagNeurod4tm1KagNeurog2tm1FguNeurog2tm1FguNeurog2tm1FguNeurod4tm1Kag
• abnormal retinal layer morphology_Ascl1<tm1And>/Ascl1<tm1And>,Neurod4<tm1Kag>/Neurod4<tm1Kag>,Neurog2<tm1Fgu>/Neurog2<tm1Fgu>
  http://metadb.riken.jp/0003727I129SvC57BL6CBAICRAscl1tm1AndAscl1tm1AndNeurod4tm1KagNeurod4tm1KagNeurog2tm1FguNeurog2tm1FguNeurod4tm1KagAscl1tm1AndNeurog2tm1Fgu
• decreased retinal photoreceptor cell number_Ascl1<tm1And>/Ascl1<tm1And>,Neurod1<tm1Jle>/Neurod1<tm1Jle>
  http://metadb.riken.jp/0001327EI129S1Sv129S4SvJaeSor129X1SvJICRorI129S2SvPas129S4SvJaeSorICRAscl1tm1AndAscl1tm1AndNeurod1tm1JleNeurod1tm1JleAscl1tm1AndNeurod1tm1Jle
• perinatal lethality, complete penetrance_Neurod1<tm1Jle>/Neurod1<tm1Jle>,Neurog2<tm1Fgu>/Neurog2<tm1Fgu>
  http://metadb.riken.jp/0011089I129S1Sv129S4SvJaeSor129X1SvJNeurod1tm1JleNeurod1tm1JleNeurog2tm1FguNeurog2tm1FguNeurod1tm1JleNeurog2tm1Fgu
• abnormal horizontal cell morphology_Ascl1<tm1And>/Ascl1<tm1And>,Neurod4<tm1Kag>/Neurod4<tm1Kag>,Neurog2<tm1Fgu>/Neurog2<tm1Fgu>
  http://metadb.riken.jp/0006068I129SvC57BL6CBAICRAscl1tm1AndAscl1tm1AndNeurod4tm1KagNeurod4tm1KagNeurog2tm1FguNeurog2tm1FguNeurod4tm1KagAscl1tm1AndNeurog2tm1Fgu
• increased retinal ganglion cell number_Ascl1<tm1And>/Ascl1<tm1And>,Neurod1<tm1Jle>/Neurod1<tm1Jle>,Neurod4<tm1Kag>/Neurod4<tm1Kag>
  http://metadb.riken.jp/0002983I129SvC57BL6CBAICRAscl1tm1AndAscl1tm1AndNeurod1tm1JleNeurod1tm1JleNeurod4tm1KagNeurod4tm1KagNeurod1tm1JleNeurod4tm1KagAscl1tm1And
• disorganized retinal outer nuclear layer_Neurod1<tm1Jle>/Neurod1<tm1Jle>,Neurod4<tm1Kag>/Neurod4<tm1Kag>,Neurog2<tm1Fgu>/Neurog2<tm1Fgu>
  http://metadb.riken.jp/0008516I129SvC57BL6CBAICRNeurod1tm1JleNeurod1tm1JleNeurod4tm1KagNeurod4tm1KagNeurog2tm1FguNeurog2tm1FguNeurog2tm1FguNeurod4tm1KagNeurod1tm1Jle
• abnormal Muller cell morphology_Ascl1<tm1And>/Ascl1<tm1And>,Neurod1<tm1Jle>/Neurod1<tm1Jle>,Neurod4<tm1Kag>/Neurod4<tm1Kag>
  http://metadb.riken.jp/0005547I129SvC57BL6CBAICRAscl1tm1AndAscl1tm1AndNeurod1tm1JleNeurod1tm1JleNeurod4tm1KagNeurod4tm1KagNeurod1tm1JleNeurod4tm1KagAscl1tm1And
• decreased retinal photoreceptor cell number_Neurod1<tm1Jle>/Neurod1<tm1Jle>,Neurog2<tm1Fgu>/Neurog2<tm1Fgu>
  http://metadb.riken.jp/0001327I129S1Sv129S4SvJaeSor129X1SvJNeurod1tm1JleNeurod1tm1JleNeurog2tm1FguNeurog2tm1FguNeurod1tm1JleNeurog2tm1Fgu
• decreased amacrine cell number_Neurod1<tm1Jle>/Neurod1<tm1Jle>,Neurod4<tm1Kag>/Neurod4<tm1Kag>,Neurog2<tm1Fgu>/Neurog2<tm1Fgu>
  http://metadb.riken.jp/0008106I129SvC57BL6CBAICRNeurod1tm1JleNeurod1tm1JleNeurod4tm1KagNeurod4tm1KagNeurog2tm1FguNeurog2tm1FguNeurog2tm1FguNeurod4tm1KagNeurod1tm1Jle
• abnormal retinal outer nuclear layer morphology_Neurod1<tm1Jle>/Neurod1<tm1Jle>,Neurod4<tm1Kag>/Neurod4<tm1Kag>,Neurog2<tm1Fgu>/Neurog2<tm1Fgu>
  http://metadb.riken.jp/0003731I129SvC57BL6CBAICRNeurod1tm1JleNeurod1tm1JleNeurod4tm1KagNeurod4tm1KagNeurog2tm1FguNeurog2tm1FguNeurog2tm1FguNeurod4tm1KagNeurod1tm1Jle
• decreased retinal cone cell number_Neurod1<tm1Jle>/Neurod1<tm1Jle>,Neurod4<tm1Kag>/Neurod4<tm1Kag>,Neurog2<tm1Fgu>/Neurog2<tm1Fgu>
  http://metadb.riken.jp/0008446I129SvC57BL6CBAICRNeurod1tm1JleNeurod1tm1JleNeurod4tm1KagNeurod4tm1KagNeurog2tm1FguNeurog2tm1FguNeurog2tm1FguNeurod4tm1KagNeurod1tm1Jle
• thin retinal inner nuclear layer_Neurod1<tm1Jle>/Neurod1<tm1Jle>,Neurod4<tm1Kag>/Neurod4<tm1Kag>,Neurog2<tm1Fgu>/Neurog2<tm1Fgu>
  http://metadb.riken.jp/0008511I129SvC57BL6CBAICRNeurod1tm1JleNeurod1tm1JleNeurod4tm1KagNeurod4tm1KagNeurog2tm1FguNeurog2tm1FguNeurog2tm1FguNeurod4tm1KagNeurod1tm1Jle
• perinatal lethality, complete penetrance_Ascl1<tm1And>/Ascl1<tm1And>,Neurog2<tm1Fgu>/Neurog2<tm1Fgu>
  http://metadb.riken.jp/0011089I129S1Sv129S4SvJaeSor129X1SvJICRAscl1tm1AndAscl1tm1AndNeurog2tm1FguNeurog2tm1FguAscl1tm1AndNeurog2tm1Fgu
• increased retinal ganglion cell number_Ascl1<tm1And>/Ascl1<tm1And>,Neurod4<tm1Kag>/Neurod4<tm1Kag>,Neurog2<tm1Fgu>/Neurog2<tm1Fgu>
  http://metadb.riken.jp/0002983I129SvC57BL6CBAICRAscl1tm1AndAscl1tm1AndNeurod4tm1KagNeurod4tm1KagNeurog2tm1FguNeurog2tm1FguNeurod4tm1KagAscl1tm1AndNeurog2tm1Fgu
• perinatal lethality, complete penetrance_Neurod1<tm1Jle>/Neurod1<tm1Jle>,Neurod4<tm1Kag>/Neurod4<tm1Kag>,Neurog2<tm1Fgu>/Neurog2<tm1Fgu>
  http://metadb.riken.jp/0011089I129SvC57BL6CBAICRNeurod1tm1JleNeurod1tm1JleNeurod4tm1KagNeurod4tm1KagNeurog2tm1FguNeurog2tm1FguNeurog2tm1FguNeurod4tm1KagNeurod1tm1Jle
• abnormal retinal inner nuclear layer morphology_Ascl1<tm1And>/Ascl1<tm1And>,Neurod4<tm1Kag>/Neurod4<tm1Kag>,Neurog2<tm1Fgu>/Neurog2<tm1Fgu>
  http://metadb.riken.jp/0003733I129SvC57BL6CBAICRAscl1tm1AndAscl1tm1AndNeurod4tm1KagNeurod4tm1KagNeurog2tm1FguNeurog2tm1FguNeurod4tm1KagAscl1tm1AndNeurog2tm1Fgu
• decreased retinal photoreceptor cell number_Ascl1<tm1And>/Ascl1<tm1And>,Neurod1<tm1Jle>/Neurod1<tm1Jle>,Neurod4<tm1Kag>/Neurod4<tm1Kag>
  http://metadb.riken.jp/0001327I129SvC57BL6CBAICRAscl1tm1AndAscl1tm1AndNeurod1tm1JleNeurod1tm1JleNeurod4tm1KagNeurod4tm1KagNeurod1tm1JleNeurod4tm1KagAscl1tm1And
• abnormal retinal layer morphology_Neurod1<tm1Jle>/Neurod1<tm1Jle>,Neurod4<tm1Kag>/Neurod4<tm1Kag>,Neurog2<tm1Fgu>/Neurog2<tm1Fgu>
  http://metadb.riken.jp/0003727I129SvC57BL6CBAICRNeurod1tm1JleNeurod1tm1JleNeurod4tm1KagNeurod4tm1KagNeurog2tm1FguNeurog2tm1FguNeurog2tm1FguNeurod4tm1KagNeurod1tm1Jle
• perinatal lethality, complete penetrance_Neurod1<tm1Jle>/Neurod1<tm1Jle>,Neurod4<tm1Kag>/Neurod4<tm1Kag>
  http://metadb.riken.jp/0011089I129S4SvJaeSorC57BL6CBAICRNeurod1tm1JleNeurod1tm1JleNeurod4tm1KagNeurod4tm1KagNeurod4tm1KagNeurod1tm1Jle
• decreased amacrine cell number_Ascl1<tm1And>/Ascl1<tm1And>,Neurod4<tm1Kag>/Neurod4<tm1Kag>,Neurog2<tm1Fgu>/Neurog2<tm1Fgu>
  http://metadb.riken.jp/0008106I129SvC57BL6CBAICRAscl1tm1AndAscl1tm1AndNeurod4tm1KagNeurod4tm1KagNeurog2tm1FguNeurog2tm1FguNeurod4tm1KagAscl1tm1AndNeurog2tm1Fgu
• perinatal lethality, complete penetrance_Ascl1<tm1And>/Ascl1<tm1And>,Neurod1<tm1Jle>/Neurod1<tm1Jle>,Neurod4<tm1Kag>/Neurod4<tm1Kag>
  http://metadb.riken.jp/0011089I129SvC57BL6CBAICRAscl1tm1AndAscl1tm1AndNeurod1tm1JleNeurod1tm1JleNeurod4tm1KagNeurod4tm1KagNeurod1tm1JleNeurod4tm1KagAscl1tm1And
• decreased retinal ganglion cell number_Neurod1<tm1Jle>/Neurod1<tm1Jle>,Neurod4<tm1Kag>/Neurod4<tm1Kag>,Neurog2<tm1Fgu>/Neurog2<tm1Fgu>
  http://metadb.riken.jp/0006309I129SvC57BL6CBAICRNeurod1tm1JleNeurod1tm1JleNeurod4tm1KagNeurod4tm1KagNeurog2tm1FguNeurog2tm1FguNeurog2tm1FguNeurod4tm1KagNeurod1tm1Jle
• abnormal Muller cell morphology_Neurod1<tm1Jle>/Neurod1<tm1Jle>,Neurod4<tm1Kag>/Neurod4<tm1Kag>,Neurog2<tm1Fgu>/Neurog2<tm1Fgu>
  http://metadb.riken.jp/0005547I129SvC57BL6CBAICRNeurod1tm1JleNeurod1tm1JleNeurod4tm1KagNeurod4tm1KagNeurog2tm1FguNeurog2tm1FguNeurog2tm1FguNeurod4tm1KagNeurod1tm1Jle
• increased retinal apoptosis_Neurod1<tm1Jle>/Neurod1<tm1Jle>,Neurod4<tm1Kag>/Neurod4<tm1Kag>,Neurog2<tm1Fgu>/Neurog2<tm1Fgu>
  http://metadb.riken.jp/0030005I129SvC57BL6CBAICRNeurod1tm1JleNeurod1tm1JleNeurod4tm1KagNeurod4tm1KagNeurog2tm1FguNeurog2tm1FguNeurog2tm1FguNeurod4tm1KagNeurod1tm1Jle
• abnormal retinal layer morphology_Ascl1<tm1And>/Ascl1<tm1And>,Neurod1<tm1Jle>/Neurod1<tm1Jle>,Neurod4<tm1Kag>/Neurod4<tm1Kag>
  http://metadb.riken.jp/0003727I129SvC57BL6CBAICRAscl1tm1AndAscl1tm1AndNeurod1tm1JleNeurod1tm1JleNeurod4tm1KagNeurod4tm1KagNeurod1tm1JleNeurod4tm1KagAscl1tm1And
• abnormal horizontal cell morphology_Neurod1<tm1Jle>/Neurod1<tm1Jle>,Neurod4<tm1Kag>/Neurod4<tm1Kag>,Neurog2<tm1Fgu>/Neurog2<tm1Fgu>
  http://metadb.riken.jp/0006068I129SvC57BL6CBAICRNeurod1tm1JleNeurod1tm1JleNeurod4tm1KagNeurod4tm1KagNeurog2tm1FguNeurog2tm1FguNeurog2tm1FguNeurod4tm1KagNeurod1tm1Jle
• abnormal retinal inner nuclear layer morphology_Ascl1<tm1And>/Ascl1<tm1And>,Neurod1<tm1Jle>/Neurod1<tm1Jle>,Neurod4<tm1Kag>/Neurod4<tm1Kag>
  http://metadb.riken.jp/0003733I129SvC57BL6CBAICRAscl1tm1AndAscl1tm1AndNeurod1tm1JleNeurod1tm1JleNeurod4tm1KagNeurod4tm1KagNeurod1tm1JleNeurod4tm1KagAscl1tm1And
• perinatal lethality, complete penetrance_Ascl1<tm1And>/Ascl1<tm1And>,Neurod1<tm1Jle>/Neurod1<tm1Jle>
  http://metadb.riken.jp/0011089EI129S1Sv129S4SvJaeSor129X1SvJICRorI129S2SvPas129S4SvJaeSorICRAscl1tm1AndAscl1tm1AndNeurod1tm1JleNeurod1tm1JleAscl1tm1AndNeurod1tm1Jle
• abnormal retinal bipolar cell morphology_Ascl1<tm1And>/Ascl1<tm1And>,Neurod4<tm1Kag>/Neurod4<tm1Kag>,Neurog2<tm1Fgu>/Neurog2<tm1Fgu>
  http://metadb.riken.jp/0006073I129SvC57BL6CBAICRAscl1tm1AndAscl1tm1AndNeurod4tm1KagNeurod4tm1KagNeurog2tm1FguNeurog2tm1FguNeurod4tm1KagAscl1tm1AndNeurog2tm1Fgu
• decreased retinal photoreceptor cell number_Neurod1<tm1Jle>/Neurod1<tm1Jle>,Neurod4<tm1Kag>/Neurod4<tm1Kag>
  http://metadb.riken.jp/0001327I129S4SvJaeSorC57BL6CBAICRNeurod1tm1JleNeurod1tm1JleNeurod4tm1KagNeurod4tm1KagNeurod4tm1KagNeurod1tm1Jle
• abnormal retinal inner nuclear layer morphology_Neurod1<tm1Jle>/Neurod1<tm1Jle>,Neurod4<tm1Kag>/Neurod4<tm1Kag>,Neurog2<tm1Fgu>/Neurog2<tm1Fgu>
  http://metadb.riken.jp/0003733I129SvC57BL6CBAICRNeurod1tm1JleNeurod1tm1JleNeurod4tm1KagNeurod4tm1KagNeurog2tm1FguNeurog2tm1FguNeurog2tm1FguNeurod4tm1KagNeurod1tm1Jle
• abnormal retinal bipolar cell morphology_Ascl1<tm1And>/Ascl1<tm1And>,Neurod1<tm1Jle>/Neurod1<tm1Jle>,Neurod4<tm1Kag>/Neurod4<tm1Kag>
  http://metadb.riken.jp/0006073I129SvC57BL6CBAICRAscl1tm1AndAscl1tm1AndNeurod1tm1JleNeurod1tm1JleNeurod4tm1KagNeurod4tm1KagNeurod1tm1JleNeurod4tm1KagAscl1tm1And
• abnormal Muller cell morphology_Ascl1<tm1And>/Ascl1<tm1And>,Neurod4<tm1Kag>/Neurod4<tm1Kag>,Neurog2<tm1Fgu>/Neurog2<tm1Fgu>
  http://metadb.riken.jp/0005547I129SvC57BL6CBAICRAscl1tm1AndAscl1tm1AndNeurod4tm1KagNeurod4tm1KagNeurog2tm1FguNeurog2tm1FguNeurod4tm1KagAscl1tm1AndNeurog2tm1Fgu
• decreased retinal photoreceptor cell number_Neurod4<tm1Kag>/Neurod4<tm1Kag>,Neurog2<tm1Fgu>/Neurog2<tm1Fgu>
  http://metadb.riken.jp/0001327I129S1Sv129X1SvJC57BL6CBAICRNeurod4tm1KagNeurod4tm1KagNeurog2tm1FguNeurog2tm1FguNeurog2tm1FguNeurod4tm1Kag
• increased retinal apoptosis_Neurod1<tm1Jle>/Neurod1<tm1Jle>
  http://metadb.riken.jp/0030005I129S4SvJaeSorICRNeurod1tm1JleNeurod1tm1JleNeurod1tm1Jle
• increased retinal apoptosis_Ascl1<tm1And>/Ascl1<tm1And>,Neurod1<tm1Jle>/Neurod1<tm1Jle>,Neurod4<tm1Kag>/Neurod4<tm1Kag>
  http://metadb.riken.jp/0030005I129SvC57BL6CBAICRAscl1tm1AndAscl1tm1AndNeurod1tm1JleNeurod1tm1JleNeurod4tm1KagNeurod4tm1KagNeurod1tm1JleNeurod4tm1KagAscl1tm1And
• abnormal retinal bipolar cell morphology_Neurod1<tm1Jle>/Neurod1<tm1Jle>,Neurod4<tm1Kag>/Neurod4<tm1Kag>,Neurog2<tm1Fgu>/Neurog2<tm1Fgu>
  http://metadb.riken.jp/0006073I129SvC57BL6CBAICRNeurod1tm1JleNeurod1tm1JleNeurod4tm1KagNeurod4tm1KagNeurog2tm1FguNeurog2tm1FguNeurog2tm1FguNeurod4tm1KagNeurod1tm1Jle
• perinatal lethality, complete penetrance_Ascl1<tm1And>/Ascl1<tm1And>,Neurod4<tm1Kag>/Neurod4<tm1Kag>
  http://metadb.riken.jp/0011089I129SvC57BL6CBAICRAscl1tm1AndAscl1tm1AndNeurod4tm1KagNeurod4tm1KagAscl1tm1AndNeurod4tm1Kag
• decreased retinal photoreceptor cell number_Neurod1<tm1Jle>/Neurod1<tm1Jle>,Neurod4<tm1Kag>/Neurod4<tm1Kag>,Neurog2<tm1Fgu>/Neurog2<tm1Fgu>
  http://metadb.riken.jp/0001327I129SvC57BL6CBAICRNeurod1tm1JleNeurod1tm1JleNeurod4tm1KagNeurod4tm1KagNeurog2tm1FguNeurog2tm1FguNeurog2tm1FguNeurod4tm1KagNeurod1tm1Jle
• abnormal retinal neuronal layer morphology_Neurod1<tm1Jle>/Neurod1<tm1Jle>,Neurod4<tm1Kag>/Neurod4<tm1Kag>,Neurog2<tm1Fgu>/Neurog2<tm1Fgu>
  http://metadb.riken.jp/0006069I129SvC57BL6CBAICRNeurod1tm1JleNeurod1tm1JleNeurod4tm1KagNeurod4tm1KagNeurog2tm1FguNeurog2tm1FguNeurog2tm1FguNeurod4tm1KagNeurod1tm1Jle
• abnormal retinal photoreceptor layer morphology_Neurod1<tm1Jle>/Neurod1<tm1Jle>,Neurod4<tm1Kag>/Neurod4<tm1Kag>,Neurog2<tm1Fgu>/Neurog2<tm1Fgu>
  http://metadb.riken.jp/0003728I129SvC57BL6CBAICRNeurod1tm1JleNeurod1tm1JleNeurod4tm1KagNeurod4tm1KagNeurog2tm1FguNeurog2tm1FguNeurog2tm1FguNeurod4tm1KagNeurod1tm1Jle