Ruth. Ashery-Padan, et.al., Conditional inactivation of Pax6 in the pancreas causes early onset of diabetes., Developmental biology, 2004, 269

http://rdf.ncbi.nlm.nih.gov/pubmed/15110714

Ruth. Ashery-Padan, et.al., Conditional inactivation of Pax6 in the pancreas causes early onset of diabetes., Developmental biology, 2004, 269

pubmed

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• decreased circulating insulin level_Pax6<tm1Pgr>/Pax6<tm2Pgr>,Tg(Pax6-cre,GFP)1Pgr/0
  http://metadb.riken.jp/0002727I129S1Sv129X1SvJFVBNMRIPax6tm1PgrPax6tm2PgrTgPax6creGFP1Pgr0Pax6tm2PgrPax6tm1PgrTgPax6creGFP1Pgr
• postnatal growth retardation_Pax6<tm1Pgr>/Pax6<tm2Pgr>,Tg(Pax6-cre,GFP)1Pgr/0
  http://metadb.riken.jp/0001732I129S1Sv129X1SvJFVBNMRIPax6tm1PgrPax6tm2PgrTgPax6creGFP1Pgr0Pax6tm2PgrPax6tm1PgrTgPax6creGFP1Pgr
• hyperglycemia_Pax6<tm1Pgr>/Pax6<tm2Pgr>,Tg(Pax6-cre,GFP)1Pgr/0
  http://metadb.riken.jp/0001559I129S1Sv129X1SvJFVBNMRIPax6tm1PgrPax6tm2PgrTgPax6creGFP1Pgr0Pax6tm2PgrPax6tm1PgrTgPax6creGFP1Pgr
• decreased pancreatic beta cell number_Pax6<tm2Pgr>/Pax6<tm2Pgr>,Tg(Pax6-cre,GFP)1Pgr/0
  http://metadb.riken.jp/0003339IFVBNMRIPax6tm2PgrPax6tm2PgrTgPax6creGFP1Pgr0Pax6tm2PgrTgPax6creGFP1Pgr
• decreased pancreatic beta cell number_Pax6<tm1Pgr>/Pax6<tm2Pgr>,Tg(Pax6-cre,GFP)1Pgr/0
  http://metadb.riken.jp/0003339I129S1Sv129X1SvJFVBNMRIPax6tm1PgrPax6tm2PgrTgPax6creGFP1Pgr0Pax6tm2PgrPax6tm1PgrTgPax6creGFP1Pgr
• decreased pancreatic alpha cell number_Pax6<tm1Pgr>/Pax6<tm2Pgr>,Tg(Pax6-cre,GFP)1Pgr/0
  http://metadb.riken.jp/0009177I129S1Sv129X1SvJFVBNMRIPax6tm1PgrPax6tm2PgrTgPax6creGFP1Pgr0Pax6tm2PgrPax6tm1PgrTgPax6creGFP1Pgr
• decreased pancreatic beta cell number_Pax6<tm2Pgr>/Pax6<tm2Pgr>,Tg(Pdx1-cre)6Cvw/0
  http://metadb.riken.jp/0003339IFVBNMRIPax6tm2PgrPax6tm2PgrTgPdx1cre6Cvw0Pax6tm2PgrTgPdx1cre6Cvw
• postnatal lethality, complete penetrance_Pax6<tm1Pgr>/Pax6<tm2Pgr>,Tg(Pax6-cre,GFP)1Pgr/0
  http://metadb.riken.jp/0011085I129S1Sv129X1SvJFVBNMRIPax6tm1PgrPax6tm2PgrTgPax6creGFP1Pgr0Pax6tm2PgrPax6tm1PgrTgPax6creGFP1Pgr
• postnatal lethality, complete penetrance_Pax6<tm2Pgr>/Pax6<tm2Pgr>,Tg(Pdx1-cre)6Cvw/0
  http://metadb.riken.jp/0011085IFVBNMRIPax6tm2PgrPax6tm2PgrTgPdx1cre6Cvw0Pax6tm2PgrTgPdx1cre6Cvw
• increased circulating ketone body level_Pax6<tm2Pgr>/Pax6<tm2Pgr>,Tg(Pax6-cre,GFP)1Pgr/0
  http://metadb.riken.jp/0002575IFVBNMRIPax6tm2PgrPax6tm2PgrTgPax6creGFP1Pgr0Pax6tm2PgrTgPax6creGFP1Pgr
• hyperglycemia_Pax6<tm2Pgr>/Pax6<tm2Pgr>,Tg(Pax6-cre,GFP)1Pgr/0
  http://metadb.riken.jp/0001559IFVBNMRIPax6tm2PgrPax6tm2PgrTgPax6creGFP1Pgr0Pax6tm2PgrTgPax6creGFP1Pgr
• decreased circulating insulin level_Pax6<tm2Pgr>/Pax6<tm2Pgr>,Tg(Pax6-cre,GFP)1Pgr/0
  http://metadb.riken.jp/0002727IFVBNMRIPax6tm2PgrPax6tm2PgrTgPax6creGFP1Pgr0Pax6tm2PgrTgPax6creGFP1Pgr
• postnatal lethality, complete penetrance_Pax6<tm2Pgr>/Pax6<tm2Pgr>,Tg(Pax6-cre,GFP)1Pgr/0
  http://metadb.riken.jp/0011085IFVBNMRIPax6tm2PgrPax6tm2PgrTgPax6creGFP1Pgr0Pax6tm2PgrTgPax6creGFP1Pgr
• decreased pancreatic alpha cell number_Pax6<tm2Pgr>/Pax6<tm2Pgr>,Tg(Pdx1-cre)6Cvw/0
  http://metadb.riken.jp/0009177IFVBNMRIPax6tm2PgrPax6tm2PgrTgPdx1cre6Cvw0Pax6tm2PgrTgPdx1cre6Cvw
• postnatal growth retardation_Pax6<tm2Pgr>/Pax6<tm2Pgr>,Tg(Pax6-cre,GFP)1Pgr/0
  http://metadb.riken.jp/0001732IFVBNMRIPax6tm2PgrPax6tm2PgrTgPax6creGFP1Pgr0Pax6tm2PgrTgPax6creGFP1Pgr
• increased circulating ketone body level_Pax6<tm1Pgr>/Pax6<tm2Pgr>,Tg(Pax6-cre,GFP)1Pgr/0
  http://metadb.riken.jp/0002575I129S1Sv129X1SvJFVBNMRIPax6tm1PgrPax6tm2PgrTgPax6creGFP1Pgr0Pax6tm2PgrPax6tm1PgrTgPax6creGFP1Pgr
• decreased pancreatic alpha cell number_Pax6<tm2Pgr>/Pax6<tm2Pgr>,Tg(Pax6-cre,GFP)1Pgr/0
  http://metadb.riken.jp/0009177IFVBNMRIPax6tm2PgrPax6tm2PgrTgPax6creGFP1Pgr0Pax6tm2PgrTgPax6creGFP1Pgr