Edward J. McManus, et.al., The in vivo role of PtdIns(3,4,5)P3 binding to PDK1 PH domain defined by knockin mutation., The EMBO journal, 2004, 23

http://rdf.ncbi.nlm.nih.gov/pubmed/15116068

Edward J. McManus, et.al., The in vivo role of PtdIns(3,4,5)P3 binding to PDK1 PH domain defined by knockin mutation., The EMBO journal, 2004, 23

pubmed

allele

http://purl.org/net/cito/citesAsAuthority

• Pdpk1<tm1Ejm>
  http://metadb.riken.jp/db/mgi_rdf/MGI:3043781
• Pdpk1<tm2Ejm>
  http://metadb.riken.jp/db/mgi_rdf/MGI:3043785

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• abnormal forebrain morphology_Pdpk1<tm1Ejm>/Pdpk1<tm1Ejm>
  http://metadb.riken.jp/0000783I129P2OlaHsdBALBcPdpk1tm1EjmPdpk1tm1EjmPdpk1tm1Ejm
• abnormal brain development_Pdpk1<tm1Ejm>/Pdpk1<tm1Ejm>
  http://metadb.riken.jp/0000913I129P2OlaHsdBALBcPdpk1tm1EjmPdpk1tm1EjmPdpk1tm1Ejm
• abnormal brain development_Pdpk1<tm2Ejm>/Pdpk1<tm2Ejm>
  http://metadb.riken.jp/0000913I129P2OlaHsdBALBcPdpk1tm2EjmPdpk1tm2EjmPdpk1tm2Ejm
• abnormal vasculogenesis_Pdpk1<tm1Ejm>/Pdpk1<tm1Ejm>
  http://metadb.riken.jp/0001622I129P2OlaHsdBALBcPdpk1tm1EjmPdpk1tm1EjmPdpk1tm1Ejm
• abnormal embryo development_Pdpk1<tm1Ejm>/Pdpk1<tm1Ejm>
  http://metadb.riken.jp/0001672I129P2OlaHsdBALBcPdpk1tm1EjmPdpk1tm1EjmPdpk1tm1Ejm
• decreased embryo size_Pdpk1<tm1Ejm>/Pdpk1<tm1Ejm>
  http://metadb.riken.jp/0001698I129P2OlaHsdBALBcPdpk1tm1EjmPdpk1tm1EjmPdpk1tm1Ejm
他11件を見る
• abnormal placenta development_Pdpk1<tm1Ejm>/Pdpk1<tm1Ejm>
  http://metadb.riken.jp/0001712I129P2OlaHsdBALBcPdpk1tm1EjmPdpk1tm1EjmPdpk1tm1Ejm
• abnormal developmental patterning_Pdpk1<tm2Ejm>/Pdpk1<tm2Ejm>
  http://metadb.riken.jp/0002084I129P2OlaHsdBALBcPdpk1tm2EjmPdpk1tm2EjmPdpk1tm2Ejm
• abnormal extraembryonic tissue morphology_Pdpk1<tm1Ejm>/Pdpk1<tm1Ejm>
  http://metadb.riken.jp/0002086I129P2OlaHsdBALBcPdpk1tm1EjmPdpk1tm1EjmPdpk1tm1Ejm
• embryonic growth retardation_Pdpk1<tm2Ejm>/Pdpk1<tm2Ejm>
  http://metadb.riken.jp/0003984I129P2OlaHsdBALBcPdpk1tm2EjmPdpk1tm2EjmPdpk1tm2Ejm
• abnormal first pharyngeal arch morphology_Pdpk1<tm1Ejm>/Pdpk1<tm1Ejm>
  http://metadb.riken.jp/0006337I129P2OlaHsdBALBcPdpk1tm1EjmPdpk1tm1EjmPdpk1tm1Ejm
• absent dorsal root ganglion_Pdpk1<tm1Ejm>/Pdpk1<tm1Ejm>
  http://metadb.riken.jp/0008460I129P2OlaHsdBALBcPdpk1tm1EjmPdpk1tm1EjmPdpk1tm1Ejm
• embryonic lethality during organogenesis, complete penetrance_Pdpk1<tm1Ejm>/Pdpk1<tm1Ejm>
  http://metadb.riken.jp/0011098I129P2OlaHsdBALBcPdpk1tm1EjmPdpk1tm1EjmPdpk1tm1Ejm
• embryonic lethality during organogenesis, complete penetrance_Pdpk1<tm2Ejm>/Pdpk1<tm2Ejm>
  http://metadb.riken.jp/0011098I129P2OlaHsdBALBcPdpk1tm2EjmPdpk1tm2EjmPdpk1tm2Ejm
• prenatal lethality, incomplete penetrance_Pdpk1<tm2Ejm>/Pdpk1<+>
  http://metadb.riken.jp/0011101I129P2OlaHsdBALBcPdpk1tm2EjmPdpk1Pdpk1tm2EjmPdpk1
• decreased forebrain size_Pdpk1<tm1Ejm>/Pdpk1<tm1Ejm>
  http://metadb.riken.jp/0012138I129P2OlaHsdBALBcPdpk1tm1EjmPdpk1tm1EjmPdpk1tm1Ejm
• decreased forebrain size_Pdpk1<tm2Ejm>/Pdpk1<tm2Ejm>
  http://metadb.riken.jp/0012138I129P2OlaHsdBALBcPdpk1tm2EjmPdpk1tm2EjmPdpk1tm2Ejm

class

http://purl.org/net/cito/citesAsAuthority

• Pdpk1<tm1Ejm>
  http://metadb.riken.jp/db/mgi_rdf/MGI:3043781
• Pdpk1<tm2Ejm>
  http://metadb.riken.jp/db/mgi_rdf/MGI:3043785