Haruhiko. Akiyama, et.al., Interactions between Sox9 and beta-catenin control chondrocyte differentiation., Genes & development, 2004, 18

http://rdf.ncbi.nlm.nih.gov/pubmed/15132997

Haruhiko. Akiyama, et.al., Interactions between Sox9 and beta-catenin control chondrocyte differentiation., Genes & development, 2004, 18

pubmed

allele

http://purl.org/net/cito/citesAsAuthority

• Col2a1<tm1(SOX9)Crm>
  http://metadb.riken.jp/db/mgi_rdf/MGI:3045169

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• cleft secondary palate_Col2a1<tm1(SOX9)Crm>/Col2a1<+>
  http://metadb.riken.jp/0009890129SSvCol2a1tm1SOX9CrmCol2a1tm1SOX9CrmCol2a1Col2a1tm1SOX9CrmCol2a1
• lethality throughout fetal growth and development, incomplete penetrance_Ctnnb1<tm1Mmt>/Ctnnb1<+>,Tg(Col2a1-cre)1Bhr/0
  http://metadb.riken.jp/0011109I129X1SvJCtnnb1tm1MmtCtnnb1TgCol2a1cre1Bhr0Ctnnb1tm1MmtCtnnb1TgCol2a1cre1Bhr
• domed cranium_Col2a1<tm1(SOX9)Crm>/Col2a1<+>
  http://metadb.riken.jp/0000440129SSvCol2a1tm1SOX9CrmCol2a1tm1SOX9CrmCol2a1Col2a1tm1SOX9CrmCol2a1
• domed cranium_Ctnnb1<tm2Kem>/Ctnnb1<tm2Kem>,Tg(Col2a1-cre)1Bhr/0
  http://metadb.riken.jp/0000440I129S1Sv129X1SvJCtnnb1tm2KemCtnnb1tm2KemTgCol2a1cre1Bhr0TgCol2a1cre1BhrCtnnb1tm2Kem
• abnormal hyoid bone morphology_Col2a1<tm1(SOX9)Crm>/Col2a1<+>
  http://metadb.riken.jp/0003056129SSvCol2a1tm1SOX9CrmCol2a1tm1SOX9CrmCol2a1Col2a1tm1SOX9CrmCol2a1
• abnormal vertebrae morphology_Col2a1<tm1(SOX9)Crm>/Col2a1<+>
  http://metadb.riken.jp/0000137129SSvCol2a1tm1SOX9CrmCol2a1tm1SOX9CrmCol2a1Col2a1tm1SOX9CrmCol2a1
• abnormal cartilage morphology_Col2a1<tm1(SOX9)Crm>/Col2a1<+>
  http://metadb.riken.jp/0000163129SSvCol2a1tm1SOX9CrmCol2a1tm1SOX9CrmCol2a1Col2a1tm1SOX9CrmCol2a1
• neonatal lethality, incomplete penetrance_Col2a1<tm1(SOX9)Crm>/Col2a1<+>,Sox9<tm1Crm>/Sox9<+>
  http://metadb.riken.jp/0011088I129S4SvJaeCol2a1tm1SOX9CrmCol2a1Sox9tm1CrmSox9Col2a1tm1SOX9CrmCol2a1Sox9Sox9tm1Crm
• abnormal axial skeleton morphology_Col2a1<tm1(SOX9)Crm>/Col2a1<+>
  http://metadb.riken.jp/0002114129SSvCol2a1tm1SOX9CrmCol2a1tm1SOX9CrmCol2a1Col2a1tm1SOX9CrmCol2a1
• abnormal skeleton development_Col2a1<tm1(SOX9)Crm>/Col2a1<+>,Sox9<tm1Crm>/Sox9<+>
  http://metadb.riken.jp/0002113I129S4SvJaeCol2a1tm1SOX9CrmCol2a1Sox9tm1CrmSox9Col2a1tm1SOX9CrmCol2a1Sox9Sox9tm1Crm
• abnormal cartilage morphology_Ctnnb1<tm2Kem>/Ctnnb1<tm2Kem>,Tg(Col2a1-cre)1Bhr/0
  http://metadb.riken.jp/0000163I129S1Sv129X1SvJCtnnb1tm2KemCtnnb1tm2KemTgCol2a1cre1Bhr0TgCol2a1cre1BhrCtnnb1tm2Kem
• abnormal chondrocyte morphology_Ctnnb1<tm2Kem>/Ctnnb1<tm2Kem>,Tg(Col2a1-cre)1Bhr/0
  http://metadb.riken.jp/0000166I129S1Sv129X1SvJCtnnb1tm2KemCtnnb1tm2KemTgCol2a1cre1Bhr0TgCol2a1cre1BhrCtnnb1tm2Kem
• abnormal chondrocyte morphology_Col2a1<tm1(SOX9)Crm>/Col2a1<+>
  http://metadb.riken.jp/0000166129SSvCol2a1tm1SOX9CrmCol2a1tm1SOX9CrmCol2a1Col2a1tm1SOX9CrmCol2a1
• abnormal craniofacial bone morphology_Ctnnb1<tm2Kem>/Ctnnb1<tm2Kem>,Tg(Col2a1-cre)1Bhr/0
  http://metadb.riken.jp/0002116I129S1Sv129X1SvJCtnnb1tm2KemCtnnb1tm2KemTgCol2a1cre1Bhr0TgCol2a1cre1BhrCtnnb1tm2Kem
• abnormal basicranium morphology_Col2a1<tm1(SOX9)Crm>/Col2a1<+>
  http://metadb.riken.jp/0010029129SSvCol2a1tm1SOX9CrmCol2a1tm1SOX9CrmCol2a1Col2a1tm1SOX9CrmCol2a1
• respiratory distress_Col2a1<tm1(SOX9)Crm>/Col2a1<+>
  http://metadb.riken.jp/0001954129SSvCol2a1tm1SOX9CrmCol2a1tm1SOX9CrmCol2a1Col2a1tm1SOX9CrmCol2a1
• decreased body size_Col2a1<tm1(SOX9)Crm>/Col2a1<+>,Sox9<tm1Crm>/Sox9<+>
  http://metadb.riken.jp/0001265I129S4SvJaeCol2a1tm1SOX9CrmCol2a1Sox9tm1CrmSox9Col2a1tm1SOX9CrmCol2a1Sox9Sox9tm1Crm
• abnormal craniofacial bone morphology_Col2a1<tm1(SOX9)Crm>/Col2a1<+>
  http://metadb.riken.jp/0002116129SSvCol2a1tm1SOX9CrmCol2a1tm1SOX9CrmCol2a1Col2a1tm1SOX9CrmCol2a1
• small thoracic cage_Col2a1<tm1(SOX9)Crm>/Col2a1<+>
  http://metadb.riken.jp/0010103129SSvCol2a1tm1SOX9CrmCol2a1tm1SOX9CrmCol2a1Col2a1tm1SOX9CrmCol2a1
• radius hypoplasia_Col2a1<tm1(SOX9)Crm>/Col2a1<+>
  http://metadb.riken.jp/0004356129SSvCol2a1tm1SOX9CrmCol2a1tm1SOX9CrmCol2a1Col2a1tm1SOX9CrmCol2a1
• abnormal long bone epiphyseal plate morphology_Col2a1<tm1(SOX9)Crm>/Col2a1<+>
  http://metadb.riken.jp/0003055129SSvCol2a1tm1SOX9CrmCol2a1tm1SOX9CrmCol2a1Col2a1tm1SOX9CrmCol2a1
• decreased length of long bones_Col2a1<tm1(SOX9)Crm>/Col2a1<+>
  http://metadb.riken.jp/0004686129SSvCol2a1tm1SOX9CrmCol2a1tm1SOX9CrmCol2a1Col2a1tm1SOX9CrmCol2a1
• decreased length of long bones_Ctnnb1<tm2Kem>/Ctnnb1<tm2Kem>,Tg(Col2a1-cre)1Bhr/0
  http://metadb.riken.jp/0004686I129S1Sv129X1SvJCtnnb1tm2KemCtnnb1tm2KemTgCol2a1cre1Bhr0TgCol2a1cre1BhrCtnnb1tm2Kem
• short snout_Col2a1<tm1(SOX9)Crm>/Col2a1<+>
  http://metadb.riken.jp/0000445129SSvCol2a1tm1SOX9CrmCol2a1tm1SOX9CrmCol2a1Col2a1tm1SOX9CrmCol2a1
• decreased length of long bones_Ctnnb1<tm1Mmt>/Ctnnb1<+>,Tg(Col2a1-cre)1Bhr/0
  http://metadb.riken.jp/0004686I129X1SvJCtnnb1tm1MmtCtnnb1TgCol2a1cre1Bhr0Ctnnb1tm1MmtCtnnb1TgCol2a1cre1Bhr
• neonatal lethality, incomplete penetrance_Col2a1<tm1(SOX9)Crm>/Col2a1<+>
  http://metadb.riken.jp/0011088129SSvCol2a1tm1SOX9CrmCol2a1tm1SOX9CrmCol2a1Col2a1tm1SOX9CrmCol2a1
• short limbs_Ctnnb1<tm2Kem>/Ctnnb1<tm2Kem>,Tg(Col2a1-cre)1Bhr/0
  http://metadb.riken.jp/0000547I129S1Sv129X1SvJCtnnb1tm2KemCtnnb1tm2KemTgCol2a1cre1Bhr0TgCol2a1cre1BhrCtnnb1tm2Kem
• decreased body size_Col2a1<tm1(SOX9)Crm>/Col2a1<+>
  http://metadb.riken.jp/0001265129SSvCol2a1tm1SOX9CrmCol2a1tm1SOX9CrmCol2a1Col2a1tm1SOX9CrmCol2a1

class

http://purl.org/net/cito/citesAsAuthority

• Col2a1<tm1(SOX9)Crm>
  http://metadb.riken.jp/db/mgi_rdf/MGI:3045169