Ruiben. Feng, et.al., Forebrain degeneration and ventricle enlargement caused by double knockout of Alzheimer's presenilin-1 and presenilin-2., Proceedings of the National Academy of Sciences of the United States of America, 2004, 101

http://rdf.ncbi.nlm.nih.gov/pubmed/15148382

Ruiben. Feng, et.al., Forebrain degeneration and ventricle enlargement caused by double knockout of Alzheimer's presenilin-1 and presenilin-2., Proceedings of the National Academy of Sciences of the United States of America, 2004, 101

pubmed

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• enlarged lateral ventricles_Psen1<tm1Jzt>/Psen1<tm1Jzt>,Psen2<tm1Ber>/Psen2<tm1Ber>,Tg(Camk2a-cre)T29-1Stl/0
  http://metadb.riken.jp/0008535IC57BL6CBAPsen1tm1JztPsen1tm1JztPsen2tm1BerPsen2tm1BerTgCamk2acreT291Stl0Psen1tm1JztTgCamk2acreT291StlPsen2tm1Ber
• abnormal object recognition memory_Psen1<tm1Jzt>/Psen1<tm1Jzt>,Psen2<tm1Ber>/Psen2<tm1Ber>,Tg(Camk2a-cre)T29-1Stl/0
  http://metadb.riken.jp/0001458IC57BL6CBAPsen1tm1JztPsen1tm1JztPsen2tm1BerPsen2tm1BerTgCamk2acreT291Stl0Psen1tm1JztTgCamk2acreT291StlPsen2tm1Ber
• gliosis_Psen1<tm1Jzt>/Psen1<tm1Jzt>,Psen2<tm1Ber>/Psen2<tm1Ber>,Tg(Camk2a-cre)T29-1Stl/0
  http://metadb.riken.jp/0002183IC57BL6CBAPsen1tm1JztPsen1tm1JztPsen2tm1BerPsen2tm1BerTgCamk2acreT291Stl0Psen1tm1JztTgCamk2acreT291StlPsen2tm1Ber
• weight loss_Psen1<tm1Jzt>/Psen1<tm1Jzt>,Psen2<tm1Ber>/Psen2<tm1Ber>,Tg(Camk2a-cre)T29-1Stl/0
  http://metadb.riken.jp/0001263IC57BL6CBAPsen1tm1JztPsen1tm1JztPsen2tm1BerPsen2tm1BerTgCamk2acreT291Stl0Psen1tm1JztTgCamk2acreT291StlPsen2tm1Ber
• abnormal neuron morphology_Psen1<tm1Jzt>/Psen1<tm1Jzt>,Psen2<tm1Ber>/Psen2<tm1Ber>,Tg(Camk2a-cre)T29-1Stl/0
  http://metadb.riken.jp/0002882IC57BL6CBAPsen1tm1JztPsen1tm1JztPsen2tm1BerPsen2tm1BerTgCamk2acreT291Stl0Psen1tm1JztTgCamk2acreT291StlPsen2tm1Ber
• enlarged third ventricle_Psen1<tm1Jzt>/Psen1<tm1Jzt>,Psen2<tm1Ber>/Psen2<tm1Ber>,Tg(Camk2a-cre)T29-1Stl/0
  http://metadb.riken.jp/0008536IC57BL6CBAPsen1tm1JztPsen1tm1JztPsen2tm1BerPsen2tm1BerTgCamk2acreT291Stl0Psen1tm1JztTgCamk2acreT291StlPsen2tm1Ber
• abnormal apoptosis_Psen1<tm1Jzt>/Psen1<tm1Jzt>,Psen2<tm1Ber>/Psen2<tm1Ber>,Tg(Camk2a-cre)T29-1Stl/0
  http://metadb.riken.jp/0001648IC57BL6CBAPsen1tm1JztPsen1tm1JztPsen2tm1BerPsen2tm1BerTgCamk2acreT291Stl0Psen1tm1JztTgCamk2acreT291StlPsen2tm1Ber
• neurodegeneration_Psen1<tm1Jzt>/Psen1<tm1Jzt>,Psen2<tm1Ber>/Psen2<tm1Ber>,Tg(Camk2a-cre)T29-1Stl/0
  http://metadb.riken.jp/0002229IC57BL6CBAPsen1tm1JztPsen1tm1JztPsen2tm1BerPsen2tm1BerTgCamk2acreT291Stl0Psen1tm1JztTgCamk2acreT291StlPsen2tm1Ber
• abnormal hippocampus molecular cell layer_Psen1<tm1Jzt>/Psen1<tm1Jzt>,Psen2<tm1Ber>/Psen2<tm1Ber>,Tg(Camk2a-cre)T29-1Stl/0
  http://metadb.riken.jp/0008286IC57BL6CBAPsen1tm1JztPsen1tm1JztPsen2tm1BerPsen2tm1BerTgCamk2acreT291Stl0Psen1tm1JztTgCamk2acreT291StlPsen2tm1Ber
• hyperactivity_Psen1<tm1Jzt>/Psen1<tm1Jzt>,Psen2<tm1Ber>/Psen2<tm1Ber>,Tg(Camk2a-cre)T29-1Stl/0
  http://metadb.riken.jp/0001399IC57BL6CBAPsen1tm1JztPsen1tm1JztPsen2tm1BerPsen2tm1BerTgCamk2acreT291Stl0Psen1tm1JztTgCamk2acreT291StlPsen2tm1Ber
• abnormal corpus callosum morphology_Psen1<tm1Jzt>/Psen1<tm1Jzt>,Psen2<tm1Ber>/Psen2<tm1Ber>,Tg(Camk2a-cre)T29-1Stl/0
  http://metadb.riken.jp/0000780IC57BL6CBAPsen1tm1JztPsen1tm1JztPsen2tm1BerPsen2tm1BerTgCamk2acreT291Stl0Psen1tm1JztTgCamk2acreT291StlPsen2tm1Ber
• abnormal cerebral cortex morphology_Psen1<tm1Jzt>/Psen1<tm1Jzt>,Psen2<tm1Ber>/Psen2<tm1Ber>,Tg(Camk2a-cre)T29-1Stl/0
  http://metadb.riken.jp/0000788IC57BL6CBAPsen1tm1JztPsen1tm1JztPsen2tm1BerPsen2tm1BerTgCamk2acreT291Stl0Psen1tm1JztTgCamk2acreT291StlPsen2tm1Ber