Paula M. Lewis, et.al., Sonic hedgehog signaling is required for expansion of granule neuron precursors and patterning of the mouse cerebellum., Developmental biology, 2004, 270

http://rdf.ncbi.nlm.nih.gov/pubmed/15183722

Paula M. Lewis, et.al., Sonic hedgehog signaling is required for expansion of granule neuron precursors and patterning of the mouse cerebellum., Developmental biology, 2004, 270

pubmed

allele

http://purl.org/net/cito/citesAsAuthority

• Tg(Pax2-cre)1Amc
  http://metadb.riken.jp/db/mgi_rdf/MGI:3656139
• Tg(Pcp2-cre)1Amc
  http://metadb.riken.jp/db/mgi_rdf/MGI:3656031

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• abnormal cerebellar granule cell morphology_Shh<tm2Amc>/Shh<tm3Amc>,Tg(Pax2-cre)1Amc/0
  http://metadb.riken.jp/0004098I129S1Sv129X1SvJBlackSwissShhtm2AmcShhtm3AmcTgPax2cre1Amc0Shhtm2AmcTgPax2cre1AmcShhtm3Amc
• decreased Purkinje cell number_Shh<tm2Amc>/Shh<tm3Amc>,Tg(Pcp2-cre)1Amc/0
  http://metadb.riken.jp/0000880I129S1Sv129X1SvJBlackSwissShhtm2AmcShhtm3AmcTgPcp2cre1Amc0Shhtm3AmcTgPcp2cre1AmcShhtm2Amc
• abnormal cerebellar lobule formation_Shh<tm2Amc>/Shh<tm3Amc>,Tg(Pcp2-cre)1Amc/0
  http://metadb.riken.jp/0006097I129S1Sv129X1SvJBlackSwissShhtm2AmcShhtm3AmcTgPcp2cre1Amc0Shhtm3AmcTgPcp2cre1AmcShhtm2Amc
• decreased Purkinje cell number_Shh<tm2Amc>/Shh<tm3Amc>,Tg(Pax2-cre)1Amc/0
  http://metadb.riken.jp/0000880I129S1Sv129X1SvJBlackSwissShhtm2AmcShhtm3AmcTgPax2cre1Amc0Shhtm2AmcTgPax2cre1AmcShhtm3Amc
• premature death_Shh<tm2Amc>/Shh<tm3Amc>,Tg(Pax2-cre)1Amc/0
  http://metadb.riken.jp/0002083I129S1Sv129X1SvJBlackSwissShhtm2AmcShhtm3AmcTgPax2cre1Amc0Shhtm2AmcTgPax2cre1AmcShhtm3Amc
• absent cerebellar lobules_Shh<tm2Amc>/Shh<tm3Amc>,Tg(Pax2-cre)1Amc/0
  http://metadb.riken.jp/0006098I129S1Sv129X1SvJBlackSwissShhtm2AmcShhtm3AmcTgPax2cre1Amc0Shhtm2AmcTgPax2cre1AmcShhtm3Amc
• small cerebellum_Shh<tm2Amc>/Shh<tm3Amc>,Tg(Pcp2-cre)1Amc/0
  http://metadb.riken.jp/0000852I129S1Sv129X1SvJBlackSwissShhtm2AmcShhtm3AmcTgPcp2cre1Amc0Shhtm3AmcTgPcp2cre1AmcShhtm2Amc
• abnormal cerebellum development_Shh<tm2Amc>/Shh<tm3Amc>,Tg(Pax2-cre)1Amc/0
  http://metadb.riken.jp/0000854I129S1Sv129X1SvJBlackSwissShhtm2AmcShhtm3AmcTgPax2cre1Amc0Shhtm2AmcTgPax2cre1AmcShhtm3Amc
• small cerebellum_Shh<tm2Amc>/Shh<tm3Amc>,Tg(Pax2-cre)1Amc/0
  http://metadb.riken.jp/0000852I129S1Sv129X1SvJBlackSwissShhtm2AmcShhtm3AmcTgPax2cre1Amc0Shhtm2AmcTgPax2cre1AmcShhtm3Amc
• abnormal cerebellar molecular layer_Shh<tm2Amc>/Shh<tm3Amc>,Tg(Pax2-cre)1Amc/0
  http://metadb.riken.jp/0000889I129S1Sv129X1SvJBlackSwissShhtm2AmcShhtm3AmcTgPax2cre1Amc0Shhtm2AmcTgPax2cre1AmcShhtm3Amc
• abnormal cerebellar Purkinje cell layer_Shh<tm2Amc>/Shh<tm3Amc>,Tg(Pax2-cre)1Amc/0
  http://metadb.riken.jp/0000875I129S1Sv129X1SvJBlackSwissShhtm2AmcShhtm3AmcTgPax2cre1Amc0Shhtm2AmcTgPax2cre1AmcShhtm3Amc
• abnormal cerebellum development_Shh<tm2Amc>/Shh<tm3Amc>,Tg(Pcp2-cre)1Amc/0
  http://metadb.riken.jp/0000854I129S1Sv129X1SvJBlackSwissShhtm2AmcShhtm3AmcTgPcp2cre1Amc0Shhtm3AmcTgPcp2cre1AmcShhtm2Amc
• ataxia_Shh<tm2Amc>/Shh<tm3Amc>,Tg(Pax2-cre)1Amc/0
  http://metadb.riken.jp/0001393I129S1Sv129X1SvJBlackSwissShhtm2AmcShhtm3AmcTgPax2cre1Amc0Shhtm2AmcTgPax2cre1AmcShhtm3Amc
• abnormal cerebellum external granule cell layer morphology_Shh<tm2Amc>/Shh<tm3Amc>,Tg(Pax2-cre)1Amc/0
  http://metadb.riken.jp/0000872I129S1Sv129X1SvJBlackSwissShhtm2AmcShhtm3AmcTgPax2cre1Amc0Shhtm2AmcTgPax2cre1AmcShhtm3Amc
• abnormal motor capabilities/coordination/movement_Shh<tm2Amc>/Shh<tm3Amc>,Tg(Pax2-cre)1Amc/0
  http://metadb.riken.jp/0002066I129S1Sv129X1SvJBlackSwissShhtm2AmcShhtm3AmcTgPax2cre1Amc0Shhtm2AmcTgPax2cre1AmcShhtm3Amc
• abnormal cerebellar granule layer morphology_Shh<tm2Amc>/Shh<tm3Amc>,Tg(Pax2-cre)1Amc/0
  http://metadb.riken.jp/0000886I129S1Sv129X1SvJBlackSwissShhtm2AmcShhtm3AmcTgPax2cre1Amc0Shhtm2AmcTgPax2cre1AmcShhtm3Amc
• abnormal cerebellum morphology_Shh<tm2Amc>/Shh<tm3Amc>,Tg(Pcp2-cre)1Amc/0
  http://metadb.riken.jp/0000849I129S1Sv129X1SvJBlackSwissShhtm2AmcShhtm3AmcTgPcp2cre1Amc0Shhtm3AmcTgPcp2cre1AmcShhtm2Amc
• abnormal cerebellum morphology_Shh<tm2Amc>/Shh<tm3Amc>,Tg(Pax2-cre)1Amc/0
  http://metadb.riken.jp/0000849I129S1Sv129X1SvJBlackSwissShhtm2AmcShhtm3AmcTgPax2cre1Amc0Shhtm2AmcTgPax2cre1AmcShhtm3Amc
• abnormal motor capabilities/coordination/movement_Shh<tm2Amc>/Shh<tm3Amc>,Tg(Pcp2-cre)1Amc/0
  http://metadb.riken.jp/0002066I129S1Sv129X1SvJBlackSwissShhtm2AmcShhtm3AmcTgPcp2cre1Amc0Shhtm3AmcTgPcp2cre1AmcShhtm2Amc
• abnormal cerebellar Purkinje cell layer_Shh<tm2Amc>/Shh<tm3Amc>,Tg(Pcp2-cre)1Amc/0
  http://metadb.riken.jp/0000875I129S1Sv129X1SvJBlackSwissShhtm2AmcShhtm3AmcTgPcp2cre1Amc0Shhtm3AmcTgPcp2cre1AmcShhtm2Amc
• thin external granule cell layer_Shh<tm2Amc>/Shh<tm3Amc>,Tg(Pcp2-cre)1Amc/0
  http://metadb.riken.jp/0000873I129S1Sv129X1SvJBlackSwissShhtm2AmcShhtm3AmcTgPcp2cre1Amc0Shhtm3AmcTgPcp2cre1AmcShhtm2Amc
• ataxia_Shh<tm2Amc>/Shh<tm3Amc>,Tg(Pcp2-cre)1Amc/0
  http://metadb.riken.jp/0001393I129S1Sv129X1SvJBlackSwissShhtm2AmcShhtm3AmcTgPcp2cre1Amc0Shhtm3AmcTgPcp2cre1AmcShhtm2Amc
• abnormal astrocyte morphology_Shh<tm2Amc>/Shh<tm3Amc>,Tg(Pax2-cre)1Amc/0
  http://metadb.riken.jp/0002182I129S1Sv129X1SvJBlackSwissShhtm2AmcShhtm3AmcTgPax2cre1Amc0Shhtm2AmcTgPax2cre1AmcShhtm3Amc

class

http://purl.org/net/cito/citesAsAuthority

• Tg(Pax2-cre)1Amc
  http://metadb.riken.jp/db/mgi_rdf/MGI:3656139
• Tg(Pcp2-cre)1Amc
  http://metadb.riken.jp/db/mgi_rdf/MGI:3656031