Wan Cheung. Cheung, et.al., Novel targeted deregulation of c-Myc cooperates with Bcl-X(L) to cause plasma cell neoplasms in mice., The Journal of clinical investigation, 2004, 113

http://rdf.ncbi.nlm.nih.gov/pubmed/15199411

Wan Cheung. Cheung, et.al., Novel targeted deregulation of c-Myc cooperates with Bcl-X(L) to cause plasma cell neoplasms in mice., The Journal of clinical investigation, 2004, 113

pubmed

allele

http://purl.org/net/cito/citesAsAuthority

• Igha<tm1(Myc)Janz>
  http://metadb.riken.jp/db/mgi_rdf/MGI:3046399

class

http://purl.org/net/cito/citesAsAuthority

• Igha<tm1(Myc)Janz>
  http://metadb.riken.jp/db/mgi_rdf/MGI:3046399

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• increased plasma cell number_Igha<tm1(Myc)Janz>/Igha<+>
  http://metadb.riken.jp/0008097I129S1SvC57BL6Ighatm1MycJanzIghaIghatm1MycJanzIgha
• abnormal B cell apoptosis_Igha<tm1(Myc)Janz>/Igha<+>,Tg(Igk-V21-Bax)1967Bvn/0
  http://metadb.riken.jp/0008781I129S1SvC57BL6FVBNIghatm1MycJanzIghaTgIgkV21Bax1967Bvn0IghaIghatm1MycJanzTgIgkV21Bax1967Bvn
• abnormal plasma cell morphology_Igha<tm1(Myc)Janz>/Igha<+>,Tg(Igk-V21-Bax)1967Bvn/0
  http://metadb.riken.jp/0002439I129S1SvC57BL6FVBNIghatm1MycJanzIghaTgIgkV21Bax1967Bvn0IghaIghatm1MycJanzTgIgkV21Bax1967Bvn
• increased B cell derived lymphoma incidence_Igha<tm1(Myc)Janz>/Igha<+>
  http://metadb.riken.jp/0002023I129S1SvC57BL6Ighatm1MycJanzIghaIghatm1MycJanzIgha
• premature death_Igha<tm1(Myc)Janz>/Igha<+>,Tg(Igk-V21-Bax)1967Bvn/0
  http://metadb.riken.jp/0002083I129S1SvC57BL6FVBNIghatm1MycJanzIghaTgIgkV21Bax1967Bvn0IghaIghatm1MycJanzTgIgkV21Bax1967Bvn
• increased B cell proliferation_Igha<tm1(Myc)Janz>/Igha<+>
  http://metadb.riken.jp/0005154I129S1SvC57BL6Ighatm1MycJanzIghaIghatm1MycJanzIgha
• increased leukemia incidence_Igha<tm1(Myc)Janz>/Igha<+>,Tg(Igk-V21-Bax)1967Bvn/0
  http://metadb.riken.jp/0002026I129S1SvC57BL6FVBNIghatm1MycJanzIghaTgIgkV21Bax1967Bvn0IghaIghatm1MycJanzTgIgkV21Bax1967Bvn
• increased IgM level_Igha<tm1(Myc)Janz>/Igha<+>,Tg(Igk-V21-Bax)1967Bvn/0
  http://metadb.riken.jp/0002494I129S1SvC57BL6FVBNIghatm1MycJanzIghaTgIgkV21Bax1967Bvn0IghaIghatm1MycJanzTgIgkV21Bax1967Bvn
• increased IgG level_Tg(Igk-V21-Bax)1967Bvn/0
  http://metadb.riken.jp/0002493IFVBNTgIgkV21Bax1967Bvn0TgIgkV21Bax1967Bvn
• increased B cell apoptosis_Igha<tm1(Myc)Janz>/Igha<+>
  http://metadb.riken.jp/0008782I129S1SvC57BL6Ighatm1MycJanzIghaIghatm1MycJanzIgha
• increased IgG level_Igha<tm1(Myc)Janz>/Igha<+>,Tg(Igk-V21-Bax)1967Bvn/0
  http://metadb.riken.jp/0002493I129S1SvC57BL6FVBNIghatm1MycJanzIghaTgIgkV21Bax1967Bvn0IghaIghatm1MycJanzTgIgkV21Bax1967Bvn
• increased plasmacytoma incidence_Igha<tm1(Myc)Janz>/Igha<+>,Tg(Igk-V21-Bax)1967Bvn/0
  http://metadb.riken.jp/0010286I129S1SvC57BL6FVBNIghatm1MycJanzIghaTgIgkV21Bax1967Bvn0IghaIghatm1MycJanzTgIgkV21Bax1967Bvn
• enlarged spleen_Igha<tm1(Myc)Janz>/Igha<+>,Tg(Igk-V21-Bax)1967Bvn/0
  http://metadb.riken.jp/0000691I129S1SvC57BL6FVBNIghatm1MycJanzIghaTgIgkV21Bax1967Bvn0IghaIghatm1MycJanzTgIgkV21Bax1967Bvn
• increased plasma cell number_Igha<tm1(Myc)Janz>/Igha<+>,Tg(Igk-V21-Bax)1967Bvn/0
  http://metadb.riken.jp/0008097I129S1SvC57BL6FVBNIghatm1MycJanzIghaTgIgkV21Bax1967Bvn0IghaIghatm1MycJanzTgIgkV21Bax1967Bvn