Hiroyuki. Mori, et.al., Socs3 deficiency in the brain elevates leptin sensitivity and confers resistance to diet-induced obesity., Nature medicine, 2004, 10

http://rdf.ncbi.nlm.nih.gov/pubmed/15208705

Hiroyuki. Mori, et.al., Socs3 deficiency in the brain elevates leptin sensitivity and confers resistance to diet-induced obesity., Nature medicine, 2004, 10

pubmed

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• decreased body fat mass_Socs3<tm1Ayos>/Socs3<tm1Ayos>,Tg(Syn1-cre)671Jxm/0
  http://metadb.riken.jp/0014143I129C57BL6Socs3tm1AyosSocs3tm1AyosTgSyn1cre671Jxm0Socs3tm1AyosTgSyn1cre671Jxm
• weight loss_Socs3<tm1Ayos>/Socs3<tm1Ayos>,Tg(Syn1-cre)671Jxm/0
  http://metadb.riken.jp/0001263I129C57BL6Socs3tm1AyosSocs3tm1AyosTgSyn1cre671Jxm0Socs3tm1AyosTgSyn1cre671Jxm
• weight loss_Socs3<tm1Ayos>/Socs3<tm1Ayos>,Tg(Nes-cre)1Kln/0
  http://metadb.riken.jp/0001263I129C57BL6Socs3tm1AyosSocs3tm1AyosTgNescre1Kln0TgNescre1KlnSocs3tm1Ayos
• improved glucose tolerance_Socs3<tm1Ayos>/Socs3<tm1Ayos>,Tg(Syn1-cre)671Jxm/0
  http://metadb.riken.jp/0005292I129C57BL6Socs3tm1AyosSocs3tm1AyosTgSyn1cre671Jxm0Socs3tm1AyosTgSyn1cre671Jxm
• decreased body fat mass_Socs3<tm1Ayos>/Socs3<tm1Ayos>,Tg(Nes-cre)1Kln/0
  http://metadb.riken.jp/0014143I129C57BL6Socs3tm1AyosSocs3tm1AyosTgNescre1Kln0TgNescre1KlnSocs3tm1Ayos
• abnormal food intake_Socs3<tm1Ayos>/Socs3<tm1Ayos>,Tg(Nes-cre)1Kln/0
  http://metadb.riken.jp/0005449I129C57BL6Socs3tm1AyosSocs3tm1AyosTgNescre1Kln0TgNescre1KlnSocs3tm1Ayos
• increased insulin sensitivity_Socs3<tm1Ayos>/Socs3<tm1Ayos>,Tg(Nes-cre)1Kln/0
  http://metadb.riken.jp/0002891I129C57BL6Socs3tm1AyosSocs3tm1AyosTgNescre1Kln0TgNescre1KlnSocs3tm1Ayos
• improved glucose tolerance_Socs3<tm1Ayos>/Socs3<tm1Ayos>,Tg(Nes-cre)1Kln/0
  http://metadb.riken.jp/0005292I129C57BL6Socs3tm1AyosSocs3tm1AyosTgNescre1Kln0TgNescre1KlnSocs3tm1Ayos
• increased insulin sensitivity_Socs3<tm1Ayos>/Socs3<tm1Ayos>,Tg(Syn1-cre)671Jxm/0
  http://metadb.riken.jp/0002891I129C57BL6Socs3tm1AyosSocs3tm1AyosTgSyn1cre671Jxm0Socs3tm1AyosTgSyn1cre671Jxm
• decreased body weight_Socs3<tm1Ayos>/Socs3<tm1Ayos>,Tg(Nes-cre)1Kln/0
  http://metadb.riken.jp/0001262I129C57BL6Socs3tm1AyosSocs3tm1AyosTgNescre1Kln0TgNescre1KlnSocs3tm1Ayos
• decreased circulating triglyceride level_Socs3<tm1Ayos>/Socs3<tm1Ayos>,Tg(Nes-cre)1Kln/0
  http://metadb.riken.jp/0002644I129C57BL6Socs3tm1AyosSocs3tm1AyosTgNescre1Kln0TgNescre1KlnSocs3tm1Ayos
• decreased circulating triglyceride level_Socs3<tm1Ayos>/Socs3<tm1Ayos>,Tg(Syn1-cre)671Jxm/0
  http://metadb.riken.jp/0002644I129C57BL6Socs3tm1AyosSocs3tm1AyosTgSyn1cre671Jxm0Socs3tm1AyosTgSyn1cre671Jxm
• abnormal food intake_Socs3<tm1Ayos>/Socs3<tm1Ayos>,Tg(Syn1-cre)671Jxm/0
  http://metadb.riken.jp/0005449I129C57BL6Socs3tm1AyosSocs3tm1AyosTgSyn1cre671Jxm0Socs3tm1AyosTgSyn1cre671Jxm
• decreased circulating free fatty acid level_Socs3<tm1Ayos>/Socs3<tm1Ayos>,Tg(Nes-cre)1Kln/0
  http://metadb.riken.jp/0002702I129C57BL6Socs3tm1AyosSocs3tm1AyosTgNescre1Kln0TgNescre1KlnSocs3tm1Ayos
• decreased circulating free fatty acid level_Socs3<tm1Ayos>/Socs3<tm1Ayos>,Tg(Syn1-cre)671Jxm/0
  http://metadb.riken.jp/0002702I129C57BL6Socs3tm1AyosSocs3tm1AyosTgSyn1cre671Jxm0Socs3tm1AyosTgSyn1cre671Jxm
• decreased body weight_Socs3<tm1Ayos>/Socs3<tm1Ayos>,Tg(Syn1-cre)671Jxm/0
  http://metadb.riken.jp/0001262I129C57BL6Socs3tm1AyosSocs3tm1AyosTgSyn1cre671Jxm0Socs3tm1AyosTgSyn1cre671Jxm

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• decreased circulating free fatty acid level in RBRC04754
  http://metadb.riken.jp/db/rikenbrc_mouse/Phenotype_1015427
• abnormal food intake in RBRC04754
  http://metadb.riken.jp/db/rikenbrc_mouse/Phenotype_1015424
• decreased body fat mass in RBRC04754
  http://metadb.riken.jp/db/rikenbrc_mouse/Phenotype_1015423
• decreased body weight in RBRC04754
  http://metadb.riken.jp/db/rikenbrc_mouse/Phenotype_1015425
• decreased circulating triglyceride level in RBRC04754
  http://metadb.riken.jp/db/rikenbrc_mouse/Phenotype_1015428
• increased insulin sensitivity in RBRC04754
  http://metadb.riken.jp/db/rikenbrc_mouse/Phenotype_1015430
• weight loss in RBRC04754
  http://metadb.riken.jp/db/rikenbrc_mouse/Phenotype_1015426
• improved glucose tolerance in RBRC04754
  http://metadb.riken.jp/db/rikenbrc_mouse/Phenotype_1015429