Gerald C. Chu, et.al., Differential requirements for Smad4 in TGFbeta-dependent patterning of the early mouse embryo., Development (Cambridge, England), 2004, 131

http://rdf.ncbi.nlm.nih.gov/pubmed/15215210

Gerald C. Chu, et.al., Differential requirements for Smad4 in TGFbeta-dependent patterning of the early mouse embryo., Development (Cambridge, England), 2004, 131

pubmed

allele

http://purl.org/net/cito/citesAsAuthority

• Smad4<tm1.1Rob>
  http://metadb.riken.jp/db/mgi_rdf/MGI:3624263
• Smad4<tm1Rob>
  http://metadb.riken.jp/db/mgi_rdf/MGI:3624262

class

http://purl.org/net/cito/citesAsAuthority

• Smad4<tm1.1Rob>
  http://metadb.riken.jp/db/mgi_rdf/MGI:3624263
• Smad4<tm1Rob>
  http://metadb.riken.jp/db/mgi_rdf/MGI:3624262

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• embryonic lethality during organogenesis, complete penetrance_Smad4<tm1Rob>/Smad4<tm1.1Rob>,Tg(Sox2-cre)1Amc/0
  http://metadb.riken.jp/0011098I129SSvEvCD1Smad4tm1RobSmad4tm11RobTgSox2cre1Amc0Smad4tm11RobTgSox2cre1AmcSmad4tm1Rob
• abnormal proximal-distal axis patterning_Smad4<tm1.1Rob>/Smad4<tm1.1Rob>
  http://metadb.riken.jp/0001705I129SSvEvCD1Smad4tm11RobSmad4tm11RobSmad4tm11Rob
• absent foregut_Smad4<tm1Rob>/Smad4<tm1.1Rob>,Tg(Sox2-cre)1Amc/0
  http://metadb.riken.jp/0012083I129SSvEvCD1Smad4tm1RobSmad4tm11RobTgSox2cre1Amc0Smad4tm11RobTgSox2cre1AmcSmad4tm1Rob
• abnormal visceral endoderm morphology_Smad4<tm1.1Rob>/Smad4<tm1.1Rob>
  http://metadb.riken.jp/0011186I129SSvEvCD1Smad4tm11RobSmad4tm11RobSmad4tm11Rob
• abnormal hindbrain development_Smad4<tm1Rob>/Smad4<tm1.1Rob>,Tg(Sox2-cre)1Amc/0
  http://metadb.riken.jp/0006108I129SSvEvCD1Smad4tm1RobSmad4tm11RobTgSox2cre1Amc0Smad4tm11RobTgSox2cre1AmcSmad4tm1Rob
• abnormal rhombomere morphology_Smad4<tm1Rob>/Smad4<tm1.1Rob>,Tg(Sox2-cre)1Amc/0
  http://metadb.riken.jp/0000933I129SSvEvCD1Smad4tm1RobSmad4tm11RobTgSox2cre1Amc0Smad4tm11RobTgSox2cre1AmcSmad4tm1Rob
• abnormal endoderm development_Smad4<tm1.1Rob>/Smad4<tm1.1Rob>
  http://metadb.riken.jp/0001685I129SSvEvCD1Smad4tm11RobSmad4tm11RobSmad4tm11Rob
• abnormal allantois morphology_Smad4<tm1Rob>/Smad4<tm1.1Rob>,Tg(Sox2-cre)1Amc/0
  http://metadb.riken.jp/0001726I129SSvEvCD1Smad4tm1RobSmad4tm11RobTgSox2cre1Amc0Smad4tm11RobTgSox2cre1AmcSmad4tm1Rob
• abnormal embryonic epiblast morphology_Smad4<tm1.1Rob>/Smad4<tm1.1Rob>
  http://metadb.riken.jp/0003886I129SSvEvCD1Smad4tm11RobSmad4tm11RobSmad4tm11Rob
• fused somites_Smad4<tm1Rob>/Smad4<tm1.1Rob>,Tg(Sox2-cre)1Amc/0
  http://metadb.riken.jp/0011733I129SSvEvCD1Smad4tm1RobSmad4tm11RobTgSox2cre1Amc0Smad4tm11RobTgSox2cre1AmcSmad4tm1Rob
• absent hindgut_Smad4<tm1Rob>/Smad4<tm1.1Rob>,Tg(Sox2-cre)1Amc/0
  http://metadb.riken.jp/0012086I129SSvEvCD1Smad4tm1RobSmad4tm11RobTgSox2cre1Amc0Smad4tm11RobTgSox2cre1AmcSmad4tm1Rob
• absent primordial germ cells_Smad4<tm1Rob>/Smad4<tm1.1Rob>,Tg(Sox2-cre)1Amc/0
  http://metadb.riken.jp/0008393I129SSvEvCD1Smad4tm1RobSmad4tm11RobTgSox2cre1Amc0Smad4tm11RobTgSox2cre1AmcSmad4tm1Rob
• abnormal dorsal-ventral axis patterning_Smad4<tm1Rob>/Smad4<tm1.1Rob>,Tg(Sox2-cre)1Amc/0
  http://metadb.riken.jp/0001704I129SSvEvCD1Smad4tm1RobSmad4tm11RobTgSox2cre1Amc0Smad4tm11RobTgSox2cre1AmcSmad4tm1Rob
• increased stomach tumor incidence_Smad4<tm1.1Rob>/Smad4<+>
  http://metadb.riken.jp/0010301I129SSvEvCD1Smad4tm11RobSmad4Smad4Smad4tm11Rob
• abnormal rostral-caudal axis patterning_Smad4<tm1Rob>/Smad4<tm1.1Rob>,Tg(Sox2-cre)1Amc/0
  http://metadb.riken.jp/0005221I129SSvEvCD1Smad4tm1RobSmad4tm11RobTgSox2cre1Amc0Smad4tm11RobTgSox2cre1AmcSmad4tm1Rob