Damian. Brockschnieder, et.al., Cell depletion due to diphtheria toxin fragment A after Cre-mediated recombination., Molecular and cellular biology, 2004, 24

http://rdf.ncbi.nlm.nih.gov/pubmed/15314171

Damian. Brockschnieder, et.al., Cell depletion due to diphtheria toxin fragment A after Cre-mediated recombination., Molecular and cellular biology, 2004, 24

pubmed

allele

http://purl.org/net/cito/citesAsAuthority

• Gt(ROSA)26Sor<tm1(DTA)Riet>
  http://metadb.riken.jp/db/mgi_rdf/MGI:3055489

class

http://purl.org/net/cito/citesAsAuthority

• Gt(ROSA)26Sor<tm1(DTA)Riet>
  http://metadb.riken.jp/db/mgi_rdf/MGI:3055489

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• abnormal cerebral cortex morphology_Gt(ROSA)26Sor<tm1(DTA)Riet>/Gt(ROSA)26Sor<+>,Neurod6<tm1(cre)Kan>/Neurod6<+>
  http://metadb.riken.jp/0000788I129P2OlaHsdGtROSA26Sortm1DTARietGtROSA26SorNeurod6tm1creKanNeurod6Neurod6tm1creKanNeurod6GtROSA26SorGtROSA26Sortm1DTARiet
• postnatal lethality, complete penetrance_Gt(ROSA)26Sor<tm1(DTA)Riet>/Gt(ROSA)26Sor<+>,Cnp<tm1(cre)Kan>/Cnp<+>
  http://metadb.riken.jp/0011085I129P2OlaHsdGtROSA26Sortm1DTARietGtROSA26SorCnptm1creKanCnpCnptm1creKanGtROSA26SorGtROSA26Sortm1DTARietCnp
• increased circulating aspartate transaminase level_Gt(ROSA)26Sor<tm1(DTA)Riet>/Gt(ROSA)26Sor<+>,Tg(Alb1-cre)7Gsc/0
  http://metadb.riken.jp/0005343I129P2OlaHsdGtROSA26Sortm1DTARietGtROSA26SorTgAlb1cre7Gsc0TgAlb1cre7GscGtROSA26Sortm1DTARietGtROSA26Sor
• demyelination_Gt(ROSA)26Sor<tm1(DTA)Riet>/Gt(ROSA)26Sor<+>,Cnp<tm1(cre)Kan>/Cnp<+>
  http://metadb.riken.jp/0000921I129P2OlaHsdGtROSA26Sortm1DTARietGtROSA26SorCnptm1creKanCnpCnptm1creKanGtROSA26SorGtROSA26Sortm1DTARietCnp
• axon degeneration_Gt(ROSA)26Sor<tm1(DTA)Riet>/Gt(ROSA)26Sor<+>,Cnp<tm1(cre)Kan>/Cnp<+>
  http://metadb.riken.jp/0005405I129P2OlaHsdGtROSA26Sortm1DTARietGtROSA26SorCnptm1creKanCnpCnptm1creKanGtROSA26SorGtROSA26Sortm1DTARietCnp
• paraparesis_Gt(ROSA)26Sor<tm1(DTA)Riet>/Gt(ROSA)26Sor<+>,Cnp<tm1(cre)Kan>/Cnp<+>
  http://metadb.riken.jp/0009434I129P2OlaHsdGtROSA26Sortm1DTARietGtROSA26SorCnptm1creKanCnpCnptm1creKanGtROSA26SorGtROSA26Sortm1DTARietCnp
• neonatal lethality, complete penetrance_Gt(ROSA)26Sor<tm1(DTA)Riet>/Gt(ROSA)26Sor<+>,Neurod6<tm1(cre)Kan>/Neurod6<+>
  http://metadb.riken.jp/0011087I129P2OlaHsdGtROSA26Sortm1DTARietGtROSA26SorNeurod6tm1creKanNeurod6Neurod6tm1creKanNeurod6GtROSA26SorGtROSA26Sortm1DTARiet
• weight loss_Gt(ROSA)26Sor<tm1(DTA)Riet>/Gt(ROSA)26Sor<+>,Cnp<tm1(cre)Kan>/Cnp<+>
  http://metadb.riken.jp/0001263I129P2OlaHsdGtROSA26Sortm1DTARietGtROSA26SorCnptm1creKanCnpCnptm1creKanGtROSA26SorGtROSA26Sortm1DTARietCnp
• tremors_Gt(ROSA)26Sor<tm1(DTA)Riet>/Gt(ROSA)26Sor<+>,Cnp<tm1(cre)Kan>/Cnp<+>
  http://metadb.riken.jp/0000745I129P2OlaHsdGtROSA26Sortm1DTARietGtROSA26SorCnptm1creKanCnpCnptm1creKanGtROSA26SorGtROSA26Sortm1DTARietCnp
• increased circulating alanine transaminase level_Gt(ROSA)26Sor<tm1(DTA)Riet>/Gt(ROSA)26Sor<+>,Tg(Alb1-cre)7Gsc/0
  http://metadb.riken.jp/0002941I129P2OlaHsdGtROSA26Sortm1DTARietGtROSA26SorTgAlb1cre7Gsc0TgAlb1cre7GscGtROSA26Sortm1DTARietGtROSA26Sor
• decreased B cell number_Cd19<tm1(cre)Cgn>/Cd19<+>,Gt(ROSA)26Sor<tm1(DTA)Riet>/Gt(ROSA)26Sor<+>
  http://metadb.riken.jp/0005017I129P2OlaHsdCd19tm1creCgnCd19GtROSA26Sortm1DTARietGtROSA26SorCd19GtROSA26SorGtROSA26Sortm1DTARietCd19tm1creCgn
• liver degeneration_Gt(ROSA)26Sor<tm1(DTA)Riet>/Gt(ROSA)26Sor<+>,Tg(Alb1-cre)7Gsc/0
  http://metadb.riken.jp/0003103I129P2OlaHsdGtROSA26Sortm1DTARietGtROSA26SorTgAlb1cre7Gsc0TgAlb1cre7GscGtROSA26Sortm1DTARietGtROSA26Sor
• absent oligodendrocytes_Gt(ROSA)26Sor<tm1(DTA)Riet>/Gt(ROSA)26Sor<+>,Cnp<tm1(cre)Kan>/Cnp<+>
  http://metadb.riken.jp/0003647I129P2OlaHsdGtROSA26Sortm1DTARietGtROSA26SorCnptm1creKanCnpCnptm1creKanGtROSA26SorGtROSA26Sortm1DTARietCnp