Yongzhi. Cui, et.al., Inactivation of Stat5 in mouse mammary epithelium during pregnancy reveals distinct functions in cell proliferation, survival, and differentiation., Molecular and cellular biology, 2004, 24

http://rdf.ncbi.nlm.nih.gov/pubmed/15340066

Yongzhi. Cui, et.al., Inactivation of Stat5 in mouse mammary epithelium during pregnancy reveals distinct functions in cell proliferation, survival, and differentiation., Molecular and cellular biology, 2004, 24

pubmed

allele

http://purl.org/net/cito/citesAsAuthority

• Stat5b<tm1Mam>
  http://metadb.riken.jp/db/mgi_rdf/MGI:3055319
• Stat5a<tm2Mam>
  http://metadb.riken.jp/db/mgi_rdf/MGI:3055318
• Del(11Stat5a-Stat5b)1Mam
  http://metadb.riken.jp/db/mgi_rdf/MGI:3055320

class

http://purl.org/net/cito/citesAsAuthority

• Stat5b<tm1Mam>
  http://metadb.riken.jp/db/mgi_rdf/MGI:3055319
• Stat5a<tm2Mam>
  http://metadb.riken.jp/db/mgi_rdf/MGI:3055318
• Del(11Stat5a-Stat5b)1Mam
  http://metadb.riken.jp/db/mgi_rdf/MGI:3055320

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• abnormal branching of the mammary ductal tree_Stat5a<tm2Mam>/Stat5a<tm2Mam>,Stat5b<tm1Mam>/Stat5b<tm1Mam>,Tg(MMTV-cre)4Mam/0
  http://metadb.riken.jp/0000662I129S6SvEvTacBlackSwissFVBStat5atm2MamStat5atm2MamStat5btm1MamStat5btm1MamTgMMTVcre4Mam0TgMMTVcre4MamStat5atm2MamStat5btm1Mam
• abnormal milk ejection_Stat5a<tm2Mam>/Stat5a<tm2Mam>,Stat5b<tm1Mam>/Stat5b<tm1Mam>,Tg(MMTV-cre)4Mam/0
  http://metadb.riken.jp/0003838I129S6SvEvTacBlackSwissFVBStat5atm2MamStat5atm2MamStat5btm1MamStat5btm1MamTgMMTVcre4Mam0TgMMTVcre4MamStat5atm2MamStat5btm1Mam
• abnormal milk ejection_Stat5b<tm1Mam>/Stat5b<tm1Mam>,Tg(MMTV-cre)4Mam/0
  http://metadb.riken.jp/0003838I129S6SvEvTacBlackSwissFVBStat5btm1MamStat5btm1MamTgMMTVcre4Mam0Stat5btm1MamTgMMTVcre4Mam
• no abnormal phenotype detected_Stat5b<tm1Mam>/Stat5b<tm1Mam>
  http://metadb.riken.jp/0002169I129S6SvEvTacBlackSwissStat5btm1MamStat5btm1MamStat5btm1Mam
• abnormal branching of the mammary ductal tree_Stat5b<tm1Mam>/Stat5b<tm1Mam>,Tg(MMTV-cre)4Mam/0
  http://metadb.riken.jp/0000662I129S6SvEvTacBlackSwissFVBStat5btm1MamStat5btm1MamTgMMTVcre4Mam0Stat5btm1MamTgMMTVcre4Mam
• increased mammary gland apoptosis_Stat5b<tm1Mam>/Stat5b<tm1Mam>,Tg(Wap-cre)11738Mam/0
  http://metadb.riken.jp/0014126I129S6SvEvTacBlackSwissStat5btm1MamStat5btm1MamTgWapcre11738Mam0TgWapcre11738MamStat5btm1Mam
• no abnormal phenotype detected_Stat5a<tm2Mam>/Stat5a<tm2Mam>,Stat5b<tm1Mam>/Stat5b<tm1Mam>
  http://metadb.riken.jp/0002169I129S6SvEvTacBlackSwissStat5atm2MamStat5atm2MamStat5btm1MamStat5btm1MamStat5atm2MamStat5btm1Mam
• abnormal mammary gland alveolus morphology_Stat5b<tm1Mam>/Stat5b<tm1Mam>,Tg(Wap-cre)11738Mam/0
  http://metadb.riken.jp/0009506I129S6SvEvTacBlackSwissStat5btm1MamStat5btm1MamTgWapcre11738Mam0TgWapcre11738MamStat5btm1Mam
• perinatal lethality, incomplete penetrance_Del(11Stat5a-Stat5b)1Mam/Del(11Stat5a-Stat5b)1Mam
  http://metadb.riken.jp/0011090I129S6SvEvTacBlackSwissDel11Stat5aStat5b1MamDel11Stat5aStat5b1MamDel11Stat5aStat5b1Mam
• anemia_Del(11Stat5a-Stat5b)1Mam/Del(11Stat5a-Stat5b)1Mam
  http://metadb.riken.jp/0001577I129S6SvEvTacBlackSwissDel11Stat5aStat5b1MamDel11Stat5aStat5b1MamDel11Stat5aStat5b1Mam
• abnormal mammary gland alveolus morphology_Stat5a<tm2Mam>/Stat5a<tm2Mam>,Stat5b<tm1Mam>/Stat5b<tm1Mam>,Tg(Wap-cre)11738Mam/0
  http://metadb.riken.jp/0009506I129S6SvEvTacBlackSwissStat5atm2MamStat5atm2MamStat5btm1MamStat5btm1MamTgWapcre11738Mam0Stat5atm2MamTgWapcre11738MamStat5btm1Mam
• increased mammary gland apoptosis_Stat5a<tm2Mam>/Stat5a<tm2Mam>,Stat5b<tm1Mam>/Stat5b<tm1Mam>,Tg(Wap-cre)11738Mam/0
  http://metadb.riken.jp/0014126I129S6SvEvTacBlackSwissStat5atm2MamStat5atm2MamStat5btm1MamStat5btm1MamTgWapcre11738Mam0Stat5atm2MamTgWapcre11738MamStat5btm1Mam
• abnormal mammary gland epithelium physiology_Stat5a<tm2Mam>/Stat5a<tm2Mam>,Stat5b<tm1Mam>/Stat5b<tm1Mam>,Tg(Wap-cre)11738Mam/0
  http://metadb.riken.jp/0010172I129S6SvEvTacBlackSwissStat5atm2MamStat5atm2MamStat5btm1MamStat5btm1MamTgWapcre11738Mam0Stat5atm2MamTgWapcre11738MamStat5btm1Mam